Results 101 to 110 of about 33,833 (238)

Multidrug‐Resistant Anal and Perianal Tuberculosis: A Case Report From the Pneumo‐Phthisiology Department of Conakry University Hospital, Guinea

Case Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Introduction: Multidrug‐resistant (MDR) anal and perianal tuberculosis constitutes an exceptionally rare form of extrapulmonary tuberculosis. We report a case of MDR anal and perianal tuberculosis diagnosed and managed in the Pneumo‐Phthisiology Department of Ignace Deen University Hospital in Conakry, Guinea. Case Presentation: Mrs.
Oumou Hawa Diallo, Mamadou Hawa Camara, Boubacar Djelo Diallo, Thierno Mouctar Bah, Ousmane N′Namarie Camara, Aboubacar Camara, Lansana Mady Camara, Tun-Chieh Chen   +7 more
wiley   +1 more source

World TB Day 2018: The Challenge of Drug Resistant Tuberculosis. [PDF]

, 2018
On 24th March, the world commemorates the day in 1882 when Dr Robert Koch announced his discovery of Mycobacterium tuberculosis (MTB). Over 130 years later, tuberculosis (TB) continues to affect individuals, communities, and entire health systems and ...
Fletcher, Helen A, Gupta-Wright, Ankur, Rangaka, Molebogeng X, Tomlinson, Gillian S   +3 more
core   +2 more sources

Exploring the Natural Products Atlas (NPAtlas) Database for Hunting Prospective Irreversible Covalent DprE1 Inhibitors With Antitubercular Activity: An Integrated In-Silico Approach

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
As the second most deadly infectious disease worldwide after COVID‐19, tuberculosis (TB) remains a pressing global health issue, further aggravated by multidrug‐resistant TB (MDR‐TB) and extensively drug‐resistant TB (XDR‐TB) strains. There is an urgent need to identify new anti‐TB treatments and novel therapeutics to confront drug resistance.
Mahmoud A. A. Ibrahim, Doaa G. M. Mahmoud, Sherif S. Ebada, Peter A. Sidhom, Gamal A. H. Mekhemer, Mohamed-Elamir F. Hegazy, Yanshuo Han, Tarad Abalkhail, Rajib Chowdhury   +8 more
wiley   +1 more source

Exercise ventilatory inefficiency in mild to end-stage COPD [PDF]

, 2014
Ventilatory inefficiency during exercise is a key pathophysiological feature of chronic obstructive pulmonary disease. Currently, it is unknown how this physiological marker relates to clinically relevant outcomes as resting ventilatory impairment ...
Alberto Neder, J., Alencar, Maria Clara N., Arbex, Flavio F., Cory, Julia, O'Donnell, Cpnor D. J., O'Donnell, Denis E., Webb, Kathy A.   +6 more
core   +1 more source

Antibacterial and Antibiofilm Activity of 8‐Hydroxyquinoline Derivatives Against Mycobacterium and Staphylococcus Species

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Synthesis of 8‐hydroxyquinoline derivatives (QD 1‐12) from different analogues of 8‐hydroxyquinoline (HQ 1‐4). The derivatives and parent compounds were evaluated for antibacterial and antibiofilm activity against Mycobacterium tuberculosis, Mycobacterium smegmatis, methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive Staphylococcus ...
Namrita Lall, Anna‐Mari Kok, Carel B. Oosthuizen, Surjeet Verma, François Chassagne, Phuc H. Vo, Khanh‐Van Ho, Chung‐Ho Lin, Cassandra L. Quave, Danielle Twilley   +9 more
wiley   +1 more source

Intranasal Administration of Bedaquiline-Loaded Fucosylated Liposomes Provides Anti-Tubercular Activity while Reducing the Potential for Systemic Side Effects

ACS Infectious Diseases
Liposomal formulations of antibiotics for inhalation offer the potential for the delivery of high drug doses, controlled drug release kinetics in the lung, and an excellent safety profile.
Franziska Marwitz, Gabriela Hädrich, N. Redinger, Karen F W Besecke, Feng Li, Nadine Aboutara, Simone Thomsen, Michaela Cohrs, Paul Robert Neumann, Henrike Lucas, Julia Kollan, Constantin Hozsa, Robert K Gieseler, Dominik Schwudke, M. Furch, Ulrich E Schaible, Lea Ann Dailey   +16 more
semanticscholar   +1 more source

A Narrative Review of Bedaquiline and Delamanid: New Arsenals Against Multidrug‐Resistant and Extensively Drug‐Resistant Mycobacterium tuberculosis

Journal of clinical laboratory analysis (Print)
The treatment of multidrug‐resistant (MDR‐) and extensively drug‐resistant tuberculosis (XDR‐TB) is a formidable challenge. Treatment of MDR‐ and XDR‐TB using bedaquiline (BDQ) and delamanid (DLM), two newly introduced medications, is steadily increasing.
Nazanin Ahmad Khosravi, M. Sirous, A. Khosravi, M. Saki   +3 more
semanticscholar   +1 more source

2016 Pipeline Report Tuberculosis Edition [PDF]

, 2016
Over the past decade, several new options for improving TB diagnosis have become available. The past year saw considerably more progress than the previous one. However, the reality of how most TB is diagnosed—or not—remains largely unchanged.
Erica Lessem, Lindsay McKenna, Mike Frick   +2 more
core  

Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer : companion diagnostics for cancer therapy [PDF]

, 2017
Here, we performed a systematic analysis to discover new biomarkers of overall survival and tumor progression in ovarian cancer patients. More specifically, we determined whether nuclear-encoded mitochondrial genes related to mitochondrial biogenesis and
Freyer, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Magliocco, Müller, Narod, Skrzypulec-Plinta, Sotgia, Sotgia, Szállási, Unkila-Kallio   +15 more
core   +1 more source

Identification of genetic determinants of bedaquiline resistance in Mycobacterium tuberculosis in Ural region, Russia

Microbiology spectrum
Collecting data on rare Mycobacterium tuberculosis (Mtb) clinical isolates with resistance to the new anti-tuberculosis drug bedaquiline is an important task for improving antimicrobial susceptibility testing methods.
T. Umpeleva, Elena Chetverikova, D. Belyaev, N. Eremeeva, T. Boteva, L. Golubeva, D. Vakhrusheva, I. Vasilieva   +7 more
semanticscholar   +1 more source