Results 141 to 150 of about 29,860 (191)

Molecular Mechanisms Underlying Antimicrobial Resistance in Mycobacteria. [PDF]

Int J Mol Sci
López-Roa P, Esteban J, Muñoz-Egea MC.
europepmc   +1 more source

Efficacies of Sequenced Monotherapies of Mycobacterium avium Lung Infection in Mouse. [PDF]

J Infect Dis
Howe RA, Rimal B, Khandelwal J, Panthi CM, Lamichhane G.   +4 more
europepmc   +1 more source

Automated modeling of population pharmacokinetic models using nlmixr2auto: a clinical trial and real-world data study

Huang Z, Fidler M, Nyang’wa B, Standing JF, Kloprogge F.   +4 more
europepmc   +1 more source

Menaquinone depletion resensitises bedaquiline-resistant tuberculosis

Wetzel J, Dallow J, Davis E, Pearson WH, Daems S, Govaerts M, Hereijgers J, Sprangers J, Truebody B, Maes V, van Hasselt V, Leemans A, Pujari V, Vos A, Martínez Viturro CM, Enrique Gómez J, Peeters M, Gerber M, Chhabra N, Wouters A, Everaerts M, Painter H, Fathima R, Willcocks SJ, Davies C, Raeymaekers V, Clark TG, Draghia-Akli R, Fletcher H, Van Loock M, Hibberd ML, Mostowy S, Crick DC, Pym AS, Samby K, Jackson P, Trabanco AA, Larrouy-Maumus G, Steyn AJ, Stoops B, Dhar N, Aguilar-Pérez C, Lamprecht DA, Wall RJ, Koul A.   +44 more
europepmc   +1 more source

Bedaquiline Resistance: Its Emergence, Mechanism, and Prevention

Clinical Infectious Diseases, 2018
Bedaquiline, a new antituberculosis drug, has already been used in >50 countries. The emergence of bedaquiline resistance is alarming, as it may result in the rapid loss of this new drug.
Richard Anthony, Anne-Laure Bañuls
exaly   +4 more sources

Variants in Bedaquiline-Candidate-Resistance Genes: Prevalence in Bedaquiline-Naive Patients, Effect on MIC, and Association with Mycobacterium tuberculosis Lineage [PDF]

Antimicrobial Agents and Chemotherapy, 2022
: Studies have shown that variants in bedaquiline-resistance genes can occur in isolates from bedaquiline-naive patients. We assessed the prevalence of variants in all bedaquiline-candidate-resistance genes in bedaquiline-naive patients, investigated the
Robin Warren, Tim H Heupink, Fathia Ben Rached   +2 more
exaly   +2 more sources

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Bedaquiline

Reactions Weekly
Jeremy Michael Burgess, Emma Whisman, Jordan DeWitt   +2 more
  +10 more sources

Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance [PDF]

Antimicrobial Agents and Chemotherapy, 2019
Six in vitro clofazimine-resistant spontaneous mutants obtained from a wild-type or pyrazinamide-resistant ATCC reference strain were selected to evaluate bedaquiline cross-resistance. The reverse was conducted for bedaquiline mutants.
Shaheed Vally Omar, Nazir Ismail, Nabila Ismail   +2 more
exaly   +2 more sources

Bedaquiline

Reactions Weekly, 2021
  +5 more sources