Results 151 to 160 of about 29,860 (191)
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Bedaquiline and delamanid in tuberculosis
Expert Opinion on Pharmacotherapy, 2015In recent years, a pressing need to develop new, effective and safe drugs against tuberculosis (TB) has continued. Poor adherence to a long therapeutic regimen against TB, intermittent drug use, errors in medical prescriptions, low quality of old TB drugs and ineffective TB control have led to the emergence of resistant TB.Two new drugs have gained ...
S. Esposito, S. Bianchini, F. Blasi
openaire +4 more sources
Annals of Pharmacotherapy, 2013
Objective: To review the chemistry, pharmacology, microbiology, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, dosage, and administration of bedaquiline, a novel oral diarylquinoline antimycobacterial agent approved by the Food and Drug Administration for the treatment of adults with pulmonary multidrug-resistant tuberculosis (MDR-TB ...
Chahine, Elias B. +2 more
openaire +3 more sources
Objective: To review the chemistry, pharmacology, microbiology, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, dosage, and administration of bedaquiline, a novel oral diarylquinoline antimycobacterial agent approved by the Food and Drug Administration for the treatment of adults with pulmonary multidrug-resistant tuberculosis (MDR-TB ...
Chahine, Elias B. +2 more
openaire +3 more sources
Reduced susceptibility and resistance to bedaquiline in clinical M. tuberculosis isolates
Journal of Infection, 2020Sergey Borisov, Danila Zimenkov
exaly
Synthetic approaches towards bedaquiline and its derivatives
Bioorganic and Medicinal Chemistry Letters, 2020Daniel Furkert +2 more
exaly