Results 31 to 40 of about 1,231,135 (287)

Behavioural and Toxic Interaction Profile of Ketamine in Combination with Caffeine [PDF]

open access: yesBasic & Clinical Pharmacology & Toxicology, 2009
Abstract: Ketamine street tablets often contain several other compounds in addition to ketamine, among them is caffeine. The purpose of this study was to examine whether caffeine interacts with ketamine‐induced behavioural and toxic effects. Male ICR mice were treated with ketamine alone or ketamine combined with various doses of caffeine, then the ...
Hui-Ru, Hsu   +4 more
openaire   +2 more sources

Ethanol toxicity differs depending on the time of day. [PDF]

open access: yesPLoS ONE, 2018
Ethanol is one of the most commonly abused drugs and consequently its toxic and psychoactive effect has been widely investigated, although little is known about the time-dependent effects of this drug. In the present research zebrafish was used to assess
Luisa M Vera   +4 more
doaj   +1 more source

Elucidation of malachite green induced behavioural, biochemical, and histo-architectural defects in Cyprinus carpio, as piscine model

open access: yesEnvironmental and Sustainability Indicators, 2020
Colours are an indispensable portion of human survival. Malachite green (MG) is a dye with a bright hue of green, used in textile, paint, and confectionery industry. For the present study, healthy fingerlings of Cyprinus carpio were exposed to sub-lethal
Reshma Sinha, Rajinder Jindal
doaj   +1 more source

Behaviour of Imidacloprid in Fields. Toxicity for Honey Bees

open access: yes, 2005
Following evidence for the intoxication of bees, the systemic insecticide imidacloprid was suspected from the mid nineties of having harmful effects. Recently, some studies have demonstrated that imidacloprid is toxic for the bees at sub-lethal doses. These doses are evaluated in the range between 1 and 20 µg kg−1, or less.
Bonmatin, J.M.   +5 more
openaire   +2 more sources

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

Mitochondrial toxicity of drugs [PDF]

open access: yes, 2008
The introduction of this thesis concentrates on the cellular energy supplier and an important instrument in mediating cell death, mitochondrion. First, an overview is given to explain the biochemical properties of this organelle.
Waldhauser, Katri Maria
core   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques   +5 more
wiley   +1 more source

Beyond mortality: behavioural disruption and reduced plasticity as sublethal effects of per- and polyfluoroalkyl substancesBeyond mortality: behavioural disruption and reduced plasticity as sublethal effects of per- and polyfluoroalkyl substances [PDF]

open access: yesRoyal Society Open Science
Environmental pollution represents a major global threat to biodiversity, interfering with a wide range of biological processes and functions. In recent years, behaviour has gained attention as a key focus for detecting the subtle adverse effects of ...
Francesco Santi   +8 more
doaj   +1 more source

Addressing Antisocial Behaviour and Toxic Communication Online

open access: yesEuropean Journal on Criminal Policy and Research, 2023
We live in an increasingly digital society. It is a hyperconnected world; a world where digital technologies, and social media in particular, are deeply embedded in our everyday lives. Such is the nature of this hyperconnectivity that, for many of us, we would be unable to work, learn and socialise without our internet-enabled devices and online ...
Anita Lavorgna, Anastasia Powell
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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