Results 51 to 60 of about 1,231,135 (287)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Ending Youth Violence Lab: An Evidence Manifesto [PDF]

This report was first published in December 2023, and is available to download as a free PDF. This work was undertaken by the Ending Youth Violence Lab at the Behavioural Insights Team.
McBride, Tom, The Behavioural Insights Team, Axford, Nick, Humayun, Sajid, Martin, Jack   +4 more
core   +4 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developments in the theory and practice of cognitive and behavioural therapies [PDF]

, 2008
In 1993 Behavioural and Cognitive Psychotherapy published a supplement edited by Ann Hackmann with the title “Behavioural and Cognitive Psychotherapies: Past History, Current Applications and Future Registration Issues”. This was the journal's first ever
John L. Taylor, Steel, Craig, Craig Steel, Taylor, John   +3 more
core   +1 more source

Dynamic biospeckle analysis, a new tool for the fast screening of plant nematicide selectivity

Plant Methods, 2019
Background Plant feeding, free-living nematodes cause extensive damage to plant roots by direct feeding and, in the case of some trichodorid and longidorid species, through the transmission of viruses.
Felicity E. O’Callaghan, Roy Neilson, Stuart A. MacFarlane, Lionel X. Dupuy   +3 more
doaj   +1 more source

First observation on the predation of a non-arthropod species by a dung beetle species: The case of Canthon chalybaeus and the snail Bulimulus apodemetes.

PLoS ONE, 2021
We described, for the first time, a case of predation of a non-arthropod species by a dung beetle species. Canthon chalybaeus Blanchard, 1843 kills healthy individuals of the terrestrial snail Bulimulus apodemetes (D'Orbigny, 1835) showing an evident ...
Claudia M Martín, Andrea Del V Guanuco, Vieyle Cortez, José R Verdú   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Size- and polymer-dependent effects of polystyrene and polyethylene micro- and nanoplastics in zebrafish (Danio rerio)

Ecotoxicology and Environmental Safety
Microplastics (MPs) have been extensively investigated, whereas nanoplastics (NPs) are increasingly recognized as emerging contaminants with potentially greater biological concern.
Valentina Perc, Victor Wepener, Urban Dajčman, Matej Hočevar, Damjana Drobne, Sara Novak   +5 more
doaj   +1 more source