Results 71 to 80 of about 1,029,768 (285)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Effects of environmental concentrations of toxins BMAA and its isomers DAB and AEG on zebrafish larvae

open access: yesEcotoxicology and Environmental Safety
The increasing concern over the environmental presence of β-N-Methylamino-L-alanine (BMAA), a toxin primarily produced by cyanobacteria and diatoms, has stimulated numerous studies to evaluate the risk for exposed populations, mainly aquatic organisms ...
Jeanne Lichtfouse   +3 more
doaj   +1 more source

Elucidation of malachite green induced behavioural, biochemical, and histo-architectural defects in Cyprinus carpio, as piscine model

open access: yesEnvironmental and Sustainability Indicators, 2020
Colours are an indispensable portion of human survival. Malachite green (MG) is a dye with a bright hue of green, used in textile, paint, and confectionery industry. For the present study, healthy fingerlings of Cyprinus carpio were exposed to sub-lethal
Reshma Sinha, Rajinder Jindal
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Energy billing survey and RCTs

open access: yes, 2022
The Behavioural Economics Team of the Australian Government (BETA) partnered with the Australian Energy Regulator (AER) to apply behavioural insights to the design of energy bills.
Behavioural Economics Team of the Australian Government
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

EAST: Four simple ways to apply behavioural insights [PDF]

open access: yes, 2017
Owain Service, Michael Hallsworth, David Halpern,Felicity Algate, Rory Gallagher, Sam Nguyen, Simon Ruda, Michael Sanders with Marcos Pelenur, Alex Gyani, Hugo Harper, Joanne Reinhard & Elspeth Kirkman If you want to encourage a behaviour, make it ...
Behavioural Insights Team, The
core  

Safety Profile of Meswak Root Extract on Liver, Kidney, Sexual Hormones and Hematological Parameters of Rats

open access: yesNotulae Scientia Biologicae, 2012
This study was conducted to investigate the safety profile of Salvadora persica (Salvadoraceae) aqueous alcoholic root extract by carrying out acute and sub-chronic toxicity assessment in order to find out any side effect of the traditionally using of ...
Abeer Y. IBRAHIM, Souad E. El-GENGAIHI
doaj   +3 more sources

Microplastic exposure increases predictability of predator avoidance strategies in hermit crabs

open access: yesJournal of Hazardous Materials Letters, 2020
The contamination of natural systems with plastic debris has become one of the most pressing global environmental issues. Microplastics (MPs) are of particular concern because their ubiquity and small size make them available for ingestion by a range of ...
Gerrit B. Nanninga   +4 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy