Results 61 to 70 of about 1,231,135 (287)
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Pharmacokinetics, systemic toxicity, and acute behavioural effects of phenethylamine derivative 25E-NBOH in rats [PDF]
25E-NBOH is a novel psychoactive substance derived from phenylethylamine, originally synthesised in 2010 for use in emission tomography. It acts as a potent agonist of serotonin receptors and induces intense visual hallucinations.
Hrubá, Anežka
core +1 more source
Ecotoxicology and Environmental SafetyThe present investigation was carried out to develop a climbing behaviour test with periwinkles, Littorina littorea. Sublethal exposure to pollutants may jeopardize the ability of this intertidal mollusc to climb up to below the water surface and remain ...
Ionan Marigomez +2 more
doaj +1 more source
Heliyon, 2019 Caralluma dalzielii N. E. Brown (Asclepiadaceae) is a cactus-like shaped shrub widely used in traditional medicine for the treatment of rheumatoid arthritis, diabetes, infertility and impotence.
Chinenye Jane Ugwah-Oguejiofor +7 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Social isolation impairs cognition via Aβ-mediated synaptic dysfunction
Translational PsychiatrySocial isolation (SI) is a common phenomenon in the modern world, especially during the coronavirus disease 2019 pandemic, and causes lasting cognitive impairments and mental disorders.
Fang Huang +8 more
doaj +1 more source
Scientific African, 2019 Pyrethroids like Lambda Cyhalothrins, are synthetic insecticides that contaminate and modify the physico-chemical integrity of receiving water bodies and are toxic to the resident life forms.
Kelsy Alalibo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
EAST: Four simple ways to apply behavioural insights [PDF]
, 2017 Owain Service, Michael Hallsworth, David Halpern,Felicity Algate, Rory Gallagher, Sam Nguyen, Simon Ruda, Michael Sanders with Marcos Pelenur, Alex Gyani, Hugo Harper, Joanne Reinhard & Elspeth Kirkman If you want to encourage a behaviour, make it ...
Behavioural Insights Team, The
core
An intrinsic behavioural approach to the double time axis paradox [PDF]
, 2009 Behavioural theory is typically developed on the double time axis. On the other hand it is known that there are intrinsic difficulties with double time axis theorems in the input output context.
Bian, Wenming +2 more
core +2 more sources