Results 81 to 90 of about 1,231,135 (287)

Case Report: Deprescribing psychotropic medication with an adolescent boy with complex emotional and behavioural challenges

Frontiers in Child and Adolescent Psychiatry
BackgroundThe prescription of psychotropic drugs to children and youth has been on the rise. Polypharmacy—the act of prescribing multiple medications—is a risk for children and youth with emotional and behavioural challenges, as prescribers may ...
Laura Theall, Serena Atallah, Serena Atallah, Ajit Ninan, Ajit Ninan, Kim Arbeau, Alicia McLean   +6 more
doaj   +1 more source

Safety profile of 40% Garcinol from Garcinia indica in experimental rodents

Toxicology Reports, 2018
The present study was taken up to evaluate the single dose acute toxicity, 28 days and 90 days repeated dose toxicity and reproductive/developmental toxicity of standardized 40% Garcinol in experimental rodents.
Muhammed Majeed, Sarang Bani, Beena Bhat, Anjali Pandey, Lakshmi Mundkur, Prakriti Neupane   +5 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Cocktails of persistent organic pollutants lead to behavioural and reproductive toxicity

, 2017
Persistent organic pollutants (POPs) are chemicals that widely distributed in the environment and biota that could cause neurobehavioural and reproductive toxicity. As humans and animals are exposed to a complex mixture of POPs, not to a single compound,
Khezri, Abdolrahman
core  

Embryotoxicity of quantum dots in rainbow trout Oncorhynchus mykiss during hatching period

Frontiers in Marine Science, 2015
Research on quantum dots (QD) has become a major interdisciplinary area of science. Unique physic-chemical properties of QD significantly expanded areas of their application and increased the potential impact on hydrosystems.
Nijolė Kazlauskienė, Ričardas Rotomskis   +1 more
doaj   +1 more source

Behavioural toxicities of antidepressants [PDF]

British Journal of Psychiatry, 1995
J. S. Kerr, D. B. Fairweather, I. Hindmarch   +2 more
openaire   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Acute toxicity of Oreochromis niloticus fingerlings exposed to effluent from Delta State University, Abraka Nigeria boys hostel

African Scientific Reports
Studies on aquatic pollution are crucial for maintaining environmental health. This study assessed the toxicity of effluents from the male hostel site II at Delta State University (DELSU) on Oreochromis niloticus fingerlings.
Ebenezer O. Ayoola, Victor N. Enwemiwe, Hilda O. Erhenhi, Clement C. Obi, Agboola A. Adebowale, Eric Esiwo, Joyce A. Onokpasa, Robert B. Ikomi   +7 more
doaj   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Ecotoxicity of commonly used oilfield-based emulsifiers on Guinean Tilapia () using histopathology and behavioral alterations as protocol

Science Progress
This study examined the histological aberrations in the gill and liver tissues and behavioural changes of Tilapia guineensis fingerlings exposed to lethal concentrations of used Oilfield-based emulsifiers for 96 h.
Davies Ibienebo Chris, Okechukwu Kenneth Wokeh, Guillermo Téllez-Isaías, Zulhisyam Abdul Kari, Mohamad Nor Azra   +4 more
doaj   +1 more source