Results 51 to 60 of about 42,152 (307)

Epigenetically active chromatin in neonatal iWAT reveals GABPα as a potential regulator of beige adipogenesis

Frontiers in Endocrinology
BackgroundThermogenic beige adipocytes, which dissipate energy as heat, are found in neonates and adults. Recent studies show that neonatal beige adipocytes are highly plastic and contribute to >50% of beige adipocytes in adults.
Raja Gopal Reddy Mooli, Bokai Zhu, Bokai Zhu, Bokai Zhu, Saifur R. Khan, Saifur R. Khan, Saifur R. Khan, Saifur R. Khan, Veerababu Nagati, Kulandaimanuvel Antony Michealraj, Michael J. Jurczak, Sadeesh K. Ramakrishnan, Sadeesh K. Ramakrishnan   +12 more
doaj   +1 more source

Thermogenic adipose tissue in energy regulation and metabolic health

Frontiers in Endocrinology, 2023
The ability to generate thermogenic fat could be a targeted therapy to thwart obesity and improve metabolic health. Brown and beige adipocytes are two types of thermogenic fat cells that regulate energy balance. Both adipocytes share common morphological,
Siwen Xue, Derek Lee, Daniel C. Berry
doaj   +1 more source

Stability Thresholds of Atomically Dispersed Platinum Catalysts for Solar Hydrogen Production

Angewandte Chemie International Edition, EarlyView.
This work identifies a critical dispersion threshold for Pt single‐atom photocatalysts. Below this limit, isolated Pt sites remain stable under illumination and deliver up to 82‐fold higher hydrogen evolution reaction (HER) activity than Pt nanoparticles.
Juneseo Park, Sungju Yu
wiley   +1 more source

Stepping Up Human Beige Fat Cell Production

Cell Reports, 2018
Beige fat cells hold significant promise for reducing obesity and metabolic disease. Su et al. (2018) present a robust method to produce human beige adipocytes from pluripotent stem cells via the generation of an expandable intermediary population of ...
Wenli Yang, Patrick Seale
doaj   +1 more source

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

Frontiers in Endocrinology, 2023
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy expenditure, has been extensively studied as a potential avenue to combat obesity.
Khanyisani Ziqubu, Phiwayinkosi V. Dludla, Phiwayinkosi V. Dludla, Sinenhlanhla X. H. Mthembu, Sinenhlanhla X. H. Mthembu, Bongani B. Nkambule, Sihle E. Mabhida, Babalwa U. Jack, Tawanda M. Nyambuya, Sithandiwe E. Mazibuko-Mbeje   +9 more
doaj   +1 more source

More Than a Buffer in Biochemistry: Tris as an Architect and Gatekeeper of Metal–Oxo Assembly

Angewandte Chemie International Edition, EarlyView.
Tris(hydroxymethyl)aminomethane, depicted as an octopus, acts as an alkoxy ligand, chelator, and structure‐directing buffer that programs polyoxometalate's speciation, nucleation, and heterometal insertion in aqueous solution. ABSTRACT Polyoxometalates (POMs, molecular metal–oxo clusters) are typically studied and applied in aqueous media, where ...
Nadiia I. Gumerova, Annette Rompel
wiley   +1 more source

Ceiling culture of human mature white adipocytes with a browning agent: A novel approach to induce transdifferentiation into beige adipocytes

Frontiers in Bioengineering and Biotechnology, 2022
Excess and dysfunctional adipose tissue plays an important role in metabolic diseases, including obesity, atherosclerosis and type 2 diabetes mellitus. In mammals, adipose tissue is categorized into two types: white and brown.
Yufei He, Zhuokai Liang, Jing Wang, Haojing Tang, Jian Li, Junrong Cai, Yunjun Liao   +6 more
doaj   +1 more source

Brazil Nut Flour as a Functional Ingredient: Effects on Texture, Composition and Sensory Profile of Reduced‐Sugar Gluten‐Free Cookies

Journal of the American Oil Chemists' Society, EarlyView.
Graphical abstract of the characterization of Brazil nut flour (BNF) and the impact of its addition on the nutritional and sensory properties of gluten‐free and low‐sugar cookies. The results show that BNF contributed to an improved nutritional quality of the cookies and enhanced overall product acceptance.
Ana Luísa Schiessl Fabri, Lucas Lourenço dos Santos, Giustino Tribuzi, Pedro Luiz Manique Barrreto, Renata Dias de Mello Castanho Amboni, Maria Manuela Camino Feltes   +5 more
wiley   +1 more source

Iron chelation increases beige fat differentiation and metabolic activity, preventing and treating obesity

Scientific Reports, 2022
Beige and brown fat consume glucose and lipids to produce heat, using uncoupling protein 1 (UCP1). It is thought that full activation of brown adipose tissue (BAT) may increase total daily energy expenditure by 20%.
Mojgan Nazari, Kenneth W. Ho, Natasha Langley, Kuan M. Cha, Raymond Kodsi, Mawson Wang, D. Ross Laybutt, Kim Cheng, Rebecca A. Stokes, Michael M. Swarbrick, Jenny E. Gunton   +10 more
doaj   +1 more source

From Hemp Bast to Lyocell Fiber: Sustainable Process Optimization for Lyocell‐Grade Dissolving Pulp

Journal of Applied Polymer Science, EarlyView.
This study presents a sustainable method to produce lyocell‐grade dissolving pulp from Canadian hemp bast fibers. A simplified alkali‐chelation‐bleaching process, free from sulfur and chlorine, yielded high α‐cellulose pulp with low lignin and hemicellulose content. The pulp was successfully spun into continuous hemp‐based lyocell fibers, demonstrating
Md Abu Sayed, Lelia Lawson, Bernardo Araujo Souto, K. M. Abdun Noor, Dagem Z. Haddis, Frehiwot T. Hailu, Jane Batcheller, David C. Bressler, Patricia I. Dolez   +8 more
wiley   +1 more source