Results 101 to 110 of about 8,254 (159)

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

eLife
The energy-burning capability of beige adipose tissue is a potential therapeutic tool for reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we evaluate the impact of aging on the profile and activity of adipocyte stem
Corey D Holman, Alexander P Sakers, Ryan P Calhoun, Lan Cheng, Ethan C Fein, Christopher Jacobs, Linus Tsai, Evan D Rosen, Patrick Seale   +8 more
doaj   +1 more source

Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesis

Experimental and Molecular Medicine
PDGFRA+ cells have been identified as adipocyte stem cells (ASCs) that differentiate into beige adipocytes in white adipose tissue (WAT) following thermogenic stimuli.
Dong Soo Kyung, Eunmin Lee, Sehyun Chae, Yeonho Son, Ye-Jin Moon, Daehee Hwang, Jong Kyoung Kim, Yun-Hee Lee, Je Kyung Seong   +8 more
doaj   +1 more source

Corrigendum: Human abdominal subcutaneous-derived active beige adipocytes carrying FTO rs1421085 obesity-risk alleles exert lower thermogenic capacity. [PDF]

Front Cell Dev Biol, 2023
Vámos A, Arianti R, Vinnai BÁ, Alrifai R, Shaw A, Póliska S, Guba A, Csősz É, Csomós I, Mocsár G, Lányi C, Balajthy Z, Fésüs L, Kristóf E.   +13 more
europepmc   +1 more source

Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions. [PDF]

Cell Death Differ, 2023
Yang N, Wang Y, Tian Q, Wang Q, Lu Y, Sun L, Wang S, Bei Y, Ji J, Zhou H, Yang W, Yao P, Zhu W, Sun L, Huang Z, Li X, Shen P.   +16 more
europepmc   +1 more source

Jinlida Granules Reduce Obesity in db/db Mice by Activating Beige Adipocytes. [PDF]

Biomed Res Int, 2022
Zhou HR, Wang TX, Hao YY, Hou YL, Wei C, Yao B, Wu X, Huang D, Zhang H, Wu YL.   +9 more
europepmc   +1 more source

Dolutegravir Suppresses Thermogenesis via Disrupting Uncoupling Protein 1 Expression and Mitochondrial Function in Brown/Beige Adipocytes in Preclinical Models. [PDF]

J Infect Dis, 2022
Jung I, Tu-Sekine B, Jin S, Anokye-Danso F, Ahima RS, Brown TT, Kim SF.   +6 more
europepmc   +1 more source

SAMM50 Regulates Thermogenesis of Beige Adipocytes Differentiated from Human Adipose-Derived Stem Cells by Balancing Mitochondrial Dynamics. [PDF]

Int J Mol Sci, 2022
Park SJ, Shon DH, Kim JH, Ryu YH, Ko Y.
europepmc   +1 more source

Isolation of the Stromal Vascular Fraction from Adipose Tissue and Subsequent Differentiation into White or Beige Adipocytes. [PDF]

Methods Mol Biol, 2022
Farrar JS, Martin RK.
europepmc   +1 more source

Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice. [PDF]

Nat Commun, 2021
Guo DH, Yamamoto M, Hernandez CM, Khodadadi H, Baban B, Stranahan AM.   +5 more
europepmc   +1 more source

Early postnatal interactions between beige adipocytes and sympathetic neurites regulate innervation of subcutaneous fat. [PDF]

Elife, 2021
Chi J, Lin Z, Barr W, Crane A, Zhu XG, Cohen P.   +5 more
europepmc   +1 more source