Results 41 to 50 of about 69 (69)
Aging Cell, Volume 24, Issue 10, October 2025.Restriction of dietary BCAAs protects male mice from the metabolic consequences of both normal‐ and high‐protein diets. BCAA restriction also protects from hepatic cellular senescence in vivo and in vitro, especially in the context of mitochondrial stress. ABSTRACT Dietary protein is a key regulator of healthy aging in both mice and humans.
Mariah F. Calubag +14 more
wiley +1 more source
Perirenal Fat in Disease Progression: From Inflammatory Mediator to Therapeutic Target
International Journal of Urology, Volume 32, Issue 10, Page 1314-1320, October 2025.ABSTRACT Perirenal fat (PRF), the adipose tissue that encases the kidneys, has long been considered a passive energy reservoir and mechanical buffer. However, emerging evidence has identified PRF as a biologically active visceral fat depot that secretes adipocytokines, inflammatory mediators, and other bioactive molecules, and thereby contributes to ...
Eiji Kashiwagi
wiley +1 more source
The Journal of Physiology, Volume 603, Issue 19, Page 5273-5297, October 1, 2025.Abstract figure legend Fibro/adipogenic progenitors (FAPs) are cells resident in the muscle (skeletal and cardiac) niche. FAPs are active participants in the process of muscle degeneration in cardiovascular and neuromuscular diseases. Here, the accumulation of fatty and fibrous tissue is a hallmark.
Elisa Villalobos +2 more
wiley +1 more source
Advanced Science, Volume 12, Issue 35, September 18, 2025.βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang +13 more
wiley +1 more source
Oxidative Phosphorylation in Uncoupled Mitochondria
BioEssays, Volume 47, Issue 9, September 2025.Brown adipose tissue (BAT) mediates non‐shivering thermogenesis (NST) through activation of uncoupling protein 1 (UCP1). Due to the uncoupled nature of BAT, oxidative phosphorylation is an underappreciated contributor to NST. Here, we discuss the implications of Inhibitory Factor 1 modulation, an endogenous inhibitor of ATP synthase, for BAT physiology.
Henver S. Brunetta +2 more
wiley +1 more source
Metabolic characteristics and therapeutic potential of brown and ?beige? adipose tissues
Diabetes mellitus, 2014 According to the International Diabetes Federation, 10.9 million people have diabetes mellitus (DM) in Russia; however, only up to 4 million are registered. In addition, 11.9 million people have impaired glucose tolerance and impaired fasting glucose levels [1].
Marina Vladimirovna Shestakova +3 more
openaire +3 more sources
Nutritional and metabolic regulation of brown and beige adipose tissues [PDF]
Journal of Physiology and Biochemistry, 2020 Francesc Villarroya +3 more
openaire +2 more sources
CHRNA2 as a marker for activated beige adipose tissue [PDF]
Nature Reviews Endocrinology, 2018 openaire +2 more sources
Regulation of thermogenesis in Brown and Beige Adipose Tissues [PDF]
American Journal of Biomedical Science & Research, 2020 openaire +1 more source
Noncanonical beige fat thermogenesis [PDF]
Nature Reviews Endocrinology, 2017 openaire +3 more sources