Results 51 to 60 of about 1,797,962 (199)

Brown and beige adipose tissues

Journal of Applied Physiology, 2018
With the recent rediscovery of brown fat in adult humans, our outlook on adipose tissue biology has undergone a paradigm shift. While we attempt to identify, recruit, and activate classic brown fat stores in humans, identification of beige fat has also raised the possibility of browning our white fat stores.
Chechi, Kanta, van Marken Lichtenbelt, Wouter, Richard, Denis   +2 more
openaire   +1 more source

Inducible Brown Adipose Tissue, or Beige Fat, Is Anabolic for the Skeleton [PDF]

Endocrinology, 2013
Abstract It is known that insulin resistance and type 2 diabetes mellitus are associated with increased fractures and that brown adipose tissue (BAT) counteracts many if not all of the symptoms associated with type 2 diabetes. By the use of FoxC2AD+/Tg mice, a well-established model for induction of BAT, or beige fat, we present data ...
Sima, Rahman, Yalin, Lu, Piotr J, Czernik, Clifford J, Rosen, Sven, Enerback, Beata, Lecka-Czernik   +5 more
openaire   +2 more sources

Current Progress in Adipose Tissue Biology: Implications in Obesity and Its Comorbidities

Indonesian Biomedical Journal, 2020
BACKGROUND: Obesity has been decades become a highly interest study, accompanied by the realization that adipose tissue (AT) plays a major role in the regulation of metabolic function.
Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya   +2 more
doaj   +1 more source

Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT

Molecular Metabolism, 2023
Objective: Cold stimuli trigger the conversion of white adipose tissue into beige adipose tissue, which is capable of non-shivering thermogenesis. However, what process drives this activation of thermogenesis in beige fat is not well understood. Here, we
Kyung-Mi Choi, Christopher Y. Ko, Sung-Min An, Seung-Hee Cho, Douglas J. Rowland, Jung Hak Kim, Anna Fasoli, Abhijit J. Chaudhari, Donald M. Bers, John C. Yoon   +9 more
doaj   +1 more source

Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis

Genes and Diseases, 2022
Accumulating evidence from both animal and human studies suggests that activation of beige fat increases cellular energy expenditure, ultimately reducing adiposity.
Chun Xing, Duo Jiang, Yang Liu, Qiqun Tang, Haiyan Huang   +4 more
doaj   +1 more source

Role of glucocorticoid receptor (GR) in white adipose tissue beiging

Life Sciences, 2023
Glucocorticoids (GCs) play a crucial role in energy homeostasis including white adipose tissue function; however, chronic GC excess is detrimental to mammals' health. White hypertrophic adiposity is a main factor for neuroendocrine-metabolic dysfunctions in monosodium L-glutamate (MSG)-damaged hypercorticosteronemic rat.
Martín, Florencia M., Alzamendi, Ana, Harnichar, Alejandro Ezequiel, Castrogiovanni, Daniel Cayetano, Zubiría, María Guillermina, Spinedi, Eduardo Julio, Giovambattista, Andrés   +6 more
openaire   +4 more sources

White adipose tissue uptake on 18F FDG PET/CT: A case report

Radiology Case Reports
Three distinct types of adipose tissue have been characterized: brown, white, and beige. Brown adipose tissue (BAT) is typically found in specific regions including the anterior cervical, supraclavicular, axillary, and paravertebral areas.
Maria Andrea Parra Corral, MD, Jesus R. Diaz, MD   +1 more
doaj   +1 more source

Adipose Tissue as an Endocrine Organ [PDF]

, 2018
As one of the largest endocrine organs in the body, adipose tissue secrets a number of bioactive hormones, called adipokines. The expression and secretion of adipokines are tightly controlled and coordinated by physiological and pathophysiological ...
Feng, T, Hui, X
core   +1 more source

Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue

iScience, 2022
Summary: Brown adipose tissue (BAT) is a metabolically active organ that contributes to the thermogenic response to cold exposure. In addition, other thermogenic cells termed beige adipocytes are generated in white adipose tissue (WAT) by cold exposure ...
Yohko Yoshida, Ippei Shimizu, Yung-Ting Hsiao, Masayoshi Suda, Goro Katsuumi, Masahide Seki, Yutaka Suzuki, Shujiro Okuda, Tomoyoshi Soga, Tohru Minamino   +9 more
doaj   +1 more source

Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway

Redox Biology, 2017
Brown adipose tissue (BAT) is a specialized tissue critical for non-shivering thermogenesis producing heat through mitochondrial uncoupling; whereas white adipose tissue (WAT) is responsible of energy storage in the form of triglycerides. Another type of
Cristina Contreras, Rubén Nogueiras, Carlos Diéguez, Kamal Rahmouni, Miguel López   +4 more
doaj   +1 more source