Results 41 to 50 of about 9,335 (162)
Current Progress in Adipose Tissue Biology: Implications in Obesity and Its Comorbidities
Indonesian Biomedical Journal, 2020 BACKGROUND: Obesity has been decades become a highly interest study, accompanied by the realization that adipose tissue (AT) plays a major role in the regulation of metabolic function.
Anna Meiliana +2 more
doaj +1 more source
Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT
Molecular Metabolism, 2023 Objective: Cold stimuli trigger the conversion of white adipose tissue into beige adipose tissue, which is capable of non-shivering thermogenesis. However, what process drives this activation of thermogenesis in beige fat is not well understood. Here, we
Kyung-Mi Choi +9 more
doaj +1 more source
Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis
Genes and Diseases, 2022 Accumulating evidence from both animal and human studies suggests that activation of beige fat increases cellular energy expenditure, ultimately reducing adiposity.
Chun Xing +4 more
doaj +1 more source
Role of glucocorticoid receptor (GR) in white adipose tissue beiging
Life Sciences, 2023 Glucocorticoids (GCs) play a crucial role in energy homeostasis including white adipose tissue function; however, chronic GC excess is detrimental to mammals' health. White hypertrophic adiposity is a main factor for neuroendocrine-metabolic dysfunctions in monosodium L-glutamate (MSG)-damaged hypercorticosteronemic rat.
Martín, Florencia M. +6 more
openaire +4 more sources
White adipose tissue uptake on 18F FDG PET/CT: A case report
Radiology Case ReportsThree distinct types of adipose tissue have been characterized: brown, white, and beige. Brown adipose tissue (BAT) is typically found in specific regions including the anterior cervical, supraclavicular, axillary, and paravertebral areas.
Maria Andrea Parra Corral, MD +1 more
doaj +1 more source
Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue
iScience, 2022 Summary: Brown adipose tissue (BAT) is a metabolically active organ that contributes to the thermogenic response to cold exposure. In addition, other thermogenic cells termed beige adipocytes are generated in white adipose tissue (WAT) by cold exposure ...
Yohko Yoshida +9 more
doaj +1 more source
Evaluation of markers of beige adipocytes in white adipose tissue of the mouse [PDF]
Nutrition & Metabolism, 2016 There is a growing interest in exploiting the induction of beige or "brite" (brown in white) adipocytes (beigeing) to combat obesity and its comorbidities. However, there is some uncertainty regarding the best markers to evaluate the occurrence or magnitude of beigeing in white adipose tissue in the mouse model.We evaluated the transcript expression of
Garcia, Rolando A. +2 more
openaire +2 more sources
Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway
Redox Biology, 2017 Brown adipose tissue (BAT) is a specialized tissue critical for non-shivering thermogenesis producing heat through mitochondrial uncoupling; whereas white adipose tissue (WAT) is responsible of energy storage in the form of triglycerides. Another type of
Cristina Contreras +4 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
The role of brown and beige adipose tissue in glycaemic control
Molecular Aspects of Medicine, 2019 For the past decade, brown adipose tissue (BAT) has been extensively studied as a potential therapy for obesity and metabolic diseases due to its thermogenic and glucose-consuming properties. It is now clear that the function of BAT goes beyond heat production, as it also plays an important endocrine role by secreting the so-called batokines to ...
Klepac, K. +3 more
openaire +4 more sources