Results 61 to 70 of about 544,121 (186)

In vivo emergence of beige-like fat in chickens as physiological adaptation to cold environments [PDF]

, 2021
International audienceWhile it has been hypothesized that brown adipocytes responsible for mammalian thermogenesis are absent in birds, the existence of beige fat has yet to be studied directly.
Kikusato, Motoi, Toyomizu, Masaaki, Warden, Craig H, Shirakawa, Hitoshi, Warden, Craig, Sotome, Rina, Hirasawa, Akira, Collin, Anne, Furukawa, Kyohei, Shimmura, Tsuyoshi, Nochi, Tomonori, Takahashi, Hideki, Watanabe, Kouichi, Tanitaka, Yuta, Hirakawa, Ryota, Wu, Guoyao, Amo, Taku, Kuriyagawa, Anna   +17 more
core   +1 more source

The great roundleaf bat (Hipposideros armiger) as a good model for cold-induced browning of intra-abdominal white adipose tissue. [PDF]

PLoS ONE, 2014
Inducing beige fat from white adipose tissue (WAT) is considered to be a shortcut to weight loss and increasingly becoming a key area in research into treatments for obesity and related diseases.
Yao Wang, Tengteng Zhu, Shanshan Ke, Na Fang, David M Irwin, Ming Lei, Junpeng Zhang, Huizhen Shi, Shuyi Zhang, Zhe Wang   +9 more
doaj   +1 more source

The Role of Thermogenic Fat Tissue in Energy Consumption

Current Issues in Molecular Biology, 2022
Mammalian adipose tissues are broadly divided into white adipose tissue (WAT) and thermogenic fat tissue (brown adipose tissue and beige adipose tissue).
Masato Horino, Kenji Ikeda, Tetsuya Yamada   +2 more
doaj   +1 more source

Finding a Needle in a Haystack: Identification of a Beige Fat Progenitor [PDF]

Cell, 2020
Oguri and colleagues use single-cell RNA sequencing to identify a beige adipocyte precursor cell that gives rise to thermogenic adipocytes in subcutaneous adipose tissue. These beige fat progenitors are marked by PDGFRα, Sca1, and CD81 and proliferate upon activation of FAK-signaling in response to the cold and irisin.
openaire   +2 more sources

Mitochondrial Uncoupling and Thermogenesis in Beige Fat [PDF]

Biophysical Journal, 2014
Beige adipocytes are a morphologically distinct type of fat cell that develop within white fat depots upon exposure to cold or high fat diet. These cells have emerged as a major contributor to adaptive thermogenenesis and control of obesity, along with brown fat, a classic thermogenic tissue. Indeed, similarly to brown adipocytes, beige adipocytes have
openaire   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

IRX3 Overexpression Enhances Ucp1 Expression In Vivo

Frontiers in Endocrinology, 2021
ObjectiveThe Iroquois homeobox 3 (IRX3) gene was recently reported to be a functional downstream target of a common polymorphism in the FTO gene, which encodes an obesity-associated protein; however, the role of IRX3 in energy expenditure remains unclear.
Zhiyin Zhang, Zhiyin Zhang, Qihan Wu, Qihan Wu, Yang He, Yang He, Peng Lu, Peng Lu, Danjie Li, Danjie Li, Minglan Yang, Minglan Yang, Weiqiong Gu, Weiqiong Gu, Ruixin Liu, Ruixin Liu, Jie Hong, Jie Hong, Jiqiu Wang, Jiqiu Wang   +19 more
doaj   +1 more source

Dissecting the dissection laboratory: Elements for designing a human anatomy laboratory

Anatomical Sciences Education, EarlyView.
Abstract The human anatomy dissection laboratory is a critical component of anatomical and medical education. Development, maintenance, and stocking of these laboratory spaces have unique demands, with all of the challenges in running a laboratory with Biosafety Laboratory Level 2 (BSL‐2) classification, housing a large volume of tissues saturated with
Rhiannon E. Robinson, Abbey Breckling, Danielle N. Edwards, Nicole Geske, Burhan Gharaibeh, Bobbie J. Leeper, Molly Ostwald, Mary Schilling, Bridgett Severt, Kelsey Stevens, J. P. Swigart, Jonathan J. Wisco, Melissa Zolnierz, Jeremy J. Grachan   +13 more
wiley   +1 more source

Reversing Pdgfrβ signaling restores metabolically active beige adipocytes by alleviating ILC2 suppression in aged and obese mice

Molecular Metabolism
Objective: Platelet Derived Growth Factor Receptor Beta (Pdgfrβ) suppresses the formation of cold temperature-induced beige adipocytes in aged mammals.
Abigail M. Benvie, Daniel C. Berry
doaj   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source