Results 51 to 60 of about 544,121 (186)

FAT-Richtlinie Dynamische Werkstoffkennwerte für die Crashsimulation

, 2022
Im Rahmen des AiF/FAT-Forschungsvorhabens 14205 ist die FAT-Richtline "Dynamische Werkstoffkennwerte für die Crashsimulation" (siehe [1]) zur zuverlässigen Bestimmung von crashrelevanten, dynamischen Werkstoffkennwerten für Crashsimulationen im ...
Blauel, J.G., Luke, M., Böhme, W., Rohr, I., Sun, D.-Z., Harwick, W.   +5 more
core   +1 more source

Metabolic regulation and the anti-obesity perspectives of human brown fat

Redox Biology, 2017
Activation of brown adipose tissue (BAT) in adult humans increase glucose and fatty acid clearance as well as resting metabolic rate, whereas a prolonged elevation of BAT activity improves insulin sensitivity.
Camilla Scheele, Søren Nielsen
doaj   +1 more source

Sympathetic nerve innervation is required for beigeing in white fat [PDF]

Physiological Reports, 2019
It is increasingly recognized that activation of beige adipocyte thermogenesis by pharmacological or genetic approaches increases energy expenditure and alleviates obesity. Sympathetic nervous system (SNS) directly innervating brown adipose tissue (BAT) and white adipose tissue (WAT) plays a key role in promoting nonshivering thermogenesis.
Qiang Cao, Jia Jing, Xin Cui, Hang Shi, Bingzhong Xue   +4 more
openaire   +3 more sources

A Mouse Model of Lipoatrophy Reveals Relationships Between Beige Fat Appearance and Female Fertility.

Endocrinology
White adipose tissue (WAT) performs vital metabolic and endocrine functions, but roles in female reproduction remain understudied and poorly understood.
Anaya ES, Dion W, Saha PK, Cox AR, de Groot E, Ahmed AA, Felix JB, Zhu B, Pangas SA, Hartig SM.   +9 more
europepmc   +2 more sources

Thermal stress induces glycolytic beige fat formation via a myogenic state. [PDF]

Nature, 2019
Environmental cues profoundly affect cellular plasticity in multicellular organisms. For instance, exercise promotes a glycolytic-to-oxidative fibre-type switch in skeletal muscle, and cold acclimation induces beige adipocyte biogenesis in adipose tissue.
Chen Y, Ikeda K, Yoneshiro T, Scaramozza A, Tajima K, Wang Q, Kim K, Shinoda K, Sponton CH, Brown Z, Brack A, Kajimura S.   +11 more
europepmc   +2 more sources

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis [PDF]

, 2015
SummaryType 2 innate lymphoid cells (ILC2s), an innate source of the type 2 cytokines interleukin (IL)-5 and -13, participate in the maintenance of tissue homeostasis.
Nussbaum, Jesse C, Locksley, Richard M, Mukundan, Lata, Karen Yun, Qiu, Yifu, Odegaard, Justin I., Min-Woo Lee, Yun, Karen, Lata Mukundan, Ajay Chawla, Odegaard, Justin I, Molofsky, Ari B, Lee, Min-Woo, Nussbaum, Jesse C., Ari B. Molofsky, Justin I. Odegaard, Richard M. Locksley, Chawla, Ajay, Molofsky, Ari B., Yifu Qiu, Jesse C. Nussbaum, Locksley, Richard M.   +21 more
core   +1 more source

A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes

Bio-Protocol, 2021
Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha, Beatriz Guerra, Jeremie Boucher, Marcelo Mori   +3 more
doaj   +1 more source

Ubiquitin ligase RNF20 coordinates sequential adipose thermogenesis with brown and beige fat-specific substrates. [PDF]

Nat Commun
In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli.
Jeon YG, Nahmgoong H, Oh J, Lee D, Kim DW, Kim JE, Kim YY, Ji Y, Han JS, Kim SM, Sohn JH, Lee WT, Kim SW, Park J, Huh JY, Jo K, Cho JY, Park J, Kim JB.   +18 more
europepmc   +2 more sources

Multifaceted Roles of Beige Fat in Energy Homeostasis Beyond UCP1.

Endocrinology, 2018
Beige adipocytes are an inducible form of thermogenic adipose cells that emerge within the white adipose tissue in response to a variety of environmental stimuli, such as chronic cold acclimation.
Sponton CH, Kajimura S.
europepmc   +2 more sources

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat [PDF]

, 2014
SummaryBeige fat, which expresses the thermogenic protein UCP1, provides a defense against cold and obesity. Although a cold environment is the physiologic stimulus for inducing beige fat in mice and humans, the events that lead from the sensing of cold ...
Locksley, Richard M, Nguyen, Khoa D, Odegaard, Justin I, Nguyen, Khoa D., Palmiter, Richard D., Chawla, Ajay, Palmiter, Richard D, Qiu, Yifu, Cui, Xiaojin, Locksley, Richard M., Odegaard, Justin I., Tian, Xiaoyu   +11 more
core   +1 more source