Dietary Factors Promoting Brown and Beige Fat Development and Thermogenesis [PDF]
Advances in Nutrition, 2017 Meshail Okla +2 more
exaly +2 more sources
miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]
, 2020 microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria +6 more
core +1 more source
A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes
Bio-Protocol, 2021 Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha +3 more
doaj +1 more source
PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources
The Role of Thermogenic Fat Tissue in Energy Consumption
Current Issues in Molecular Biology, 2022 Mammalian adipose tissues are broadly divided into white adipose tissue (WAT) and thermogenic fat tissue (brown adipose tissue and beige adipose tissue).
Masato Horino +2 more
doaj +1 more source
The great roundleaf bat (Hipposideros armiger) as a good model for cold-induced browning of intra-abdominal white adipose tissue. [PDF]
PLoS ONE, 2014 Inducing beige fat from white adipose tissue (WAT) is considered to be a shortcut to weight loss and increasingly becoming a key area in research into treatments for obesity and related diseases.
Yao Wang +9 more
doaj +1 more source
Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. [PDF]
Cancer Metab, 2020 Background Humans produce heat through non-shivering thermogenesis, a metabolic process that occurs in inducible beige adipocytes expressing uncoupling protein 1 (UCP1). UCP1 dissipates the proton gradient of the mitochondrial inner membrane and converts
Kawashima M +12 more
europepmc +2 more sources
Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study. [PDF]
, 2019 Spices were used as food preservatives prior to the advent of refrigeration, suggesting the possibility of effects on microbiota. Previous studies have shown prebiotic activities in animals and in vitro, but there has not been a demonstration of ...
Carpenter, Catherine L +11 more
core +1 more source
Brown and beige fat: From molecules to physiology and pathophysiology
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019 The adipose organ portrays adipocytes of diverse tones: white, brown and beige, each type with distinct functions. Adipocytes orchestrate their adaptation and expansion to provide storage to excess nutrients, the quick mobilisation of fuel to supply peripheral functional demands, insulation, and, in their thermogenic form, heat generation to maintain ...
Isabella Samuelson +9 more
openaire +4 more sources
Finding a Needle in a Haystack: Identification of a Beige Fat Progenitor [PDF]
Cell, 2020 Oguri and colleagues use single-cell RNA sequencing to identify a beige adipocyte precursor cell that gives rise to thermogenic adipocytes in subcutaneous adipose tissue. These beige fat progenitors are marked by PDGFRα, Sca1, and CD81 and proliferate upon activation of FAK-signaling in response to the cold and irisin.
openaire +3 more sources