Results 1 to 10 of about 27,594 (223)

Photoredox-catalyzed arylation of isonitriles by diaryliodonium salts towards benzamides [PDF]

Beilstein Journal of Organic Chemistry
The arylation of isonitriles by diaryliodonium salts under photoredox conditions has been proposed for the first time. The suggested procedure allows preparing a broad range of benzamides using both symmetric and unsymmetric diaryliodonium salts under ...
Nadezhda M. Metalnikova, Nikita S. Antonkin, Tuan K. Nguyen, Natalia S. Soldatova, Alexander V. Nyuchev, Mikhail A. Kinzhalov, Pavel S. Postnikov   +6 more
doaj   +2 more sources

Iodide/Nickel Co-Catalyzed Manganese-Mediated Denitrogenative Cross-Electrophile Coupling of Benzotriazinones with Alkyl Sulfonates [PDF]

Molecules
An efficient Ni-catalyzed, Mn-mediated denitrogenative cross-electrophile coupling of N-alkyl-1,2,3-benzotriazinones with alkyl tosylates and mesylates for access to o-alkyl secondary benzamides is reported.
Yingying Hong, Xuanxuan Zhang, Gang Zou
doaj   +2 more sources

Management of Clozapine Induced Hypersalivation on Slow Stream Rehabilitation Ward [PDF]

BJPsych Open
Aims: Sialorrhoea (hypersalivation), a common side effect of clozapine can impact the quality of life of patients. At present, no drugs are licensed to manage clozapine-induced hypersalivation, but there are various practical and pharmacological ...
Neeti Sud, Yousra Ghandour
doaj   +2 more sources

Palladium-Catalyzed Decarboxylative Ortho-Acylation of Tertiary Benzamides with Arylglyoxylic Acids

ACS Omega, 2017
A palladium-catalyzed ortho-acylation of tertiary benzamides using arylglyoxylic acids has been described. Unlike the palladium insertion reported to occur in the distorted N–C(O) amide bond of tertiary benzamides, the current study unveils ortho C–H ...
Joydev K. Laha, Ketul V. Patel, Sheetal Sharma   +2 more
doaj   +2 more sources

QSAR study of benzylidene hydrazine benzamides derivatives with in vitro anticancer activity against human lung cancer cell line A459 [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2023
Context: In the last decade, resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in lung cancer cases has been widespread. The discovery and development of new drugs need to be done to overcome the case.
Galih Satrio Putra, Melanny Ika Sulistyowaty, Tegar Achsendo Yuniarta, Yahmin Yahmin, Sumari Sumari, Charinrat Saechan, Takayasu Yamauchi   +6 more
doaj   +1 more source

Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

Molecules, 2021
A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl ...
Guoxiong Hua, Cameron L. Carpenter-Warren, David B. Cordes, Alexandra M. Z. Slawin, J. Derek Woollins   +4 more
doaj   +1 more source

QSAR, ADMET In Silico Pharmacokinetics, Molecular Docking and Molecular Dynamics Studies of Novel Bicyclo (Aryl Methyl) Benzamides as Potent GlyT1 Inhibitors for the Treatment of Schizophrenia

Pharmaceuticals, 2022
Forty-four bicyclo ((aryl) methyl) benzamides, acting as glycine transporter type 1 (GlyT1) inhibitors, are developed using molecular modeling techniques.
Mohamed El fadili, M. Er-rajy, Mohammed Kara, Amine Assouguem, A. Belhassan, Amal A Alotaibi, Nidal Naceiri Mrabti, H. Fidan, R. Ullah, S. Ercişli, Sara Zarougui, M. Elhallaoui   +11 more
semanticscholar   +1 more source

Base-Promoted One-Pot Synthesis of Pyridine Derivatives via Aromatic Alkyne Annulation Using Benzamides as Nitrogen Source

Molecules, 2021
In the presence of Cs2CO3, the first simple, efficient, and one-pot procedure for the synthesis of 3,5-diaryl pyridines via a variety of aromatic terminal alkynes with benzamides as the nitrogen source in sulfolane is described. The formation of pyridine
Hina Mehmood, Muhammad Asif Iqbal, Muhammad Naeem Ashiq, Ruimao Hua   +3 more
doaj   +1 more source

Structure-Based Bioisosterism Design, Synthesis, Biological Evaluation and In Silico Studies of Benzamide Analogs as Potential Anthelmintics

Molecules, 2022
A recent screen of 67,012 compounds identified a new family of compounds with excellent nematicidal activity: the ortho-substituted benzamide families Wact-11 and Wact-12.
Franco Vairoletti, Margot Paulino, Graciela Mahler, Gustavo Salinas, Cecilia Saiz   +4 more
doaj   +1 more source

Determination and structural correlation of pKBH+ for meta- and para- substituted benzamides in sulfuric acid solutions [PDF]

Journal of the Serbian Chemical Society, 2006
The protonation of some meta and para substituted benzamides in sulfuric acid solutions was studied by UV spectroscopy in the 190–350 nm region. Principal component analysis was applied to separate the effect of protonation from the medium effect.
EMIL POPOVSKI, GORAN STOJKOVIC
doaj   +3 more sources