Results 1 to 10 of about 13,813 (201)
Exploring the cocrystallization potential of urea and benzamide [PDF]
Journal of Molecular Modeling, 2018 The cocrystallization landscape of benzamide and urea interacting with aliphatic and aromatic carboxylic acids was studied both experimentally and theoretically. Ten new cocrystals of benzamide were synthesized using an oriented samples approach via a fast dropped evaporation technique. Information about types of known bi-component cocrystals augmented
Cysewski, Piotr +3 more
arxiv +7 more sources
Benzamide Trimethoprim Derivatives as Human Dihydrofolate Reductase Inhibitors—Molecular Modeling and In Vitro Activity Study [PDF]
BiomedicinesHuman dihydrofolate reductase (hDHFR) is an essential cellular enzyme, and inhibiting its activity is a promising strategy for cancer therapy. We have chosen the trimethoprim molecule (TMP) as a model compound in our search for a new class of hDHFR ...
Danuta Drozdowska +3 more
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Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists [PDF]
Molecular Pain, 2007 Agonists of TRPA1 such as mustard oil and its key component AITC cause pain and neurogenic inflammation in humans and pain behavior in rodents. TRPA1 is activated by numerous reactive compounds making it a sensor for reactive compounds in the body ...
Immke David C +6 more
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The structure of benzamide [PDF]
Acta Crystallographica, 1959 C. C. F. Blake, R. W. H. Small
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N-(4-Chlorophenyl)benzamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 The structure of the title compound, C(13)H(10)ClNO, resembles those of N-phen-ylbenzamide, N-(2-chloro-phenyl)-benzamide and other benzanilides, with similar bond parameters. The amide group -NHCO- makes a dihedral angle of 29.95 (9)° with the benzoyl ring, while the benzoyl and aniline rings form a dihedral angle of 60.76 (3)°.
B. Thimme Gowda +4 more
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N-(2,6-Dimethylphenyl)benzamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 The title compound, C(15)H(15)NO, crystallizes with two mol-ecules in the asymmetric unit. The H-N-C=O units are in a trans conformation, similar to that observed in N-(3,4-dimethyl-phen-yl)benzamide, N-(2,6-dichloro-phen-yl)benz-amide and other benzanilides.
B.T. Gowda +4 more
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N-(4-Cyanobenzyl)benzamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 The title compound, C(15)H(12)N(2)O, is a derivative of 4-(amino-meth-yl)benzonitrile, an important pestcide inter-mediate. In the crystal structure, mol-ecules are linked via inter-molecular N-H⋯O hydrogen bonds, forming infinite chains.
Yi-Li Tong +4 more
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Intramolecular C–H arylation of pyridine derivatives with a palladium catalyst for the synthesis of multiply fused heteroaromatic compounds [PDF]
Beilstein Journal of Organic ChemistryThe C–H arylation of 2-quinolinecarboxyamide bearing a C–Br bond at the N-aryl moiety is carried out with a palladium catalyst. The reaction proceeds at the C–H bond on the pyridine ring adjacent to the amide group in the presence of 10 mol % Pd(OAc)2 at
Yuki Nakanishi +3 more
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Nature CommunicationsHydrazides, N-N containing structural motifs, are important due to their presence in a wide variety of biologically significant compounds. While the homo N-N coupling of two NH moieties to form the hydrazide N-N bond is well developed, the cross ...
Subban Kathiravan +3 more
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QSAR study of benzylidene hydrazine benzamides derivatives with in vitro anticancer activity against human lung cancer cell line A459 [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: In the last decade, resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in lung cancer cases has been widespread. The discovery and development of new drugs need to be done to overcome the case.
Galih Satrio Putra +6 more
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