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A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives

open access: yesFrontiers in Pharmacology, 2021
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole scaffolds are considerably prevalent.
Shejuti Rahman Brishty   +5 more
doaj   +2 more sources

Review- biological active benzimidazole derivatives

open access: yesResults in Chemistry, 2021
In the field of Medicinal Chemistry, the uses of heterocyclic compounds increased day by day, because in many biological materials, heterocyclic compound is a part of its structure.
Balasaheb Pathare, Tanaji Bansode
doaj   +2 more sources

Research Progress on Benzimidazole Fungicides: A Review

open access: yesMolecules
Benzimidazole fungicides are a class of highly effective, low-toxicity, systemic broad-spectrum fungicides developed in the 1960s and 1970s, based on the fungicidal activity of the benzimidazole ring structure.
Song Bai   +8 more
doaj   +2 more sources

Benzimidazole scaffolds as promising antiproliferative agents: a review

open access: yesBMC Chemistry, 2019
Cancer is one of the most serious medical problem and second leading cause of death in the world, characterized by a deregulation of the cell cycle which mainly results in a progressive loss of cellular differentiation and uncontrolled cellular growth ...
Sumit Tahlan   +3 more
doaj   +2 more sources

Unraveling the mechanisms of benzimidazole resistance in hookworms: A molecular docking and dynamics study [PDF]

open access: yesJournal of Genetic Engineering and Biotechnology
Background: Benzimidazole resistance is an emerging challenge among parasitic helminths. It is caused by single nucleotide polymorphisms (SNPs) in specific loci in helminths’ β-tubulin genes.
Jan Clyden B. Tenorio   +6 more
doaj   +2 more sources

Serious adverse events reported with benzimidazole derivatives: A disproportionality analysis from the World Health Organization's pharmacovigilance database. [PDF]

open access: yesPLoS Neglected Tropical Diseases
BackgroundBenzimidazole derivatives are widely used anthelmintic drugs, particularly in mass campaigns for intestinal parasitosis treatment. Despite their generally good safety profile, serious adverse reactions have been reported.
Pamella Modingam   +2 more
doaj   +2 more sources

Monitoring of Benzimidazole Resistance in Botrytis cinerea Isolates from Strawberry in Korea and Development of Detection Method for Benzimidazole Resistance [PDF]

open access: yesThe Plant Pathology Journal, 2023
Botrytis cinerea is a major fungal plant pathogen that causes gray mold disease in strawberries, leading to a decrease in strawberry yield. While benzimidazole is widely used as a fungicide for controlling this disease, the increasing prevalence of ...
Geonwoo Kim   +5 more
doaj   +1 more source

Synthesis of ruthenium(II) carbonyl complexes with 2-monosubstituted and 1,2-disubstituted benzimidazoles [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
The reaction of the polymeric carbonyl complex [RuCl2(CO)2]x with 2-monosubstituted and 1,2-disubstituted benzimidazoles and 1,4-bis(benzimi-dazol-2-yl)benzene (L9) in 2-methoxyethanol produces various coloured complexes of the formulae [Ru(CO)2Cl2(L)2 ...
GANGA NAIK KRISHNAMURTHY   +1 more
doaj   +3 more sources

Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel β-tubulin benzimidazole resistance mutation

open access: yesPLoS Pathogens, 2023
Ancylostoma caninum is an important zoonotic gastrointestinal nematode of dogs worldwide and a close relative of human hookworms. We recently reported that racing greyhound dogs in the USA are infected with A.
Abhinaya Venkatesan   +11 more
semanticscholar   +1 more source

Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review

open access: yesAntibiotics, 2023
Bacterial infections have attracted the attention of researchers in recent decades, especially due to the special problems they have faced, such as their increasing diversity and resistance to antibiotic treatment.
M. Marinescu
semanticscholar   +1 more source

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