Unraveling the mechanisms of benzimidazole resistance in hookworms: A molecular docking and dynamics study [PDF]
Journal of Genetic Engineering and BiotechnologyBackground: Benzimidazole resistance is an emerging challenge among parasitic helminths. It is caused by single nucleotide polymorphisms (SNPs) in specific loci in helminths’ β-tubulin genes.
Jan Clyden B. Tenorio +6 more
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Serious adverse events reported with benzimidazole derivatives: A disproportionality analysis from the World Health Organization's pharmacovigilance database. [PDF]
PLoS Neglected Tropical DiseasesBackgroundBenzimidazole derivatives are widely used anthelmintic drugs, particularly in mass campaigns for intestinal parasitosis treatment. Despite their generally good safety profile, serious adverse reactions have been reported.
Pamella Modingam +2 more
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Monitoring of Benzimidazole Resistance in Botrytis cinerea Isolates from Strawberry in Korea and Development of Detection Method for Benzimidazole Resistance [PDF]
The Plant Pathology Journal, 2023 Botrytis cinerea is a major fungal plant pathogen that causes gray mold disease in strawberries, leading to a decrease in strawberry yield. While benzimidazole is widely used as a fungicide for controlling this disease, the increasing prevalence of ...
Geonwoo Kim +5 more
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Synthesis of ruthenium(II) carbonyl complexes with 2-monosubstituted and 1,2-disubstituted benzimidazoles [PDF]
Journal of the Serbian Chemical Society, 2009 The reaction of the polymeric carbonyl complex [RuCl2(CO)2]x with 2-monosubstituted and 1,2-disubstituted benzimidazoles and 1,4-bis(benzimi-dazol-2-yl)benzene (L9) in 2-methoxyethanol produces various coloured complexes of the formulae [Ru(CO)2Cl2(L)2 ...
GANGA NAIK KRISHNAMURTHY +1 more
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Synthesis and crystal structures of N-H, N-phenyl and N-benzyl-2-(4-hexyloxyphenyl)benzimidazoles
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compounds, 2-(4-hexyloxyphenyl)-1H-benzimidazole (C19H22N2O; 1), 2-(4-hexyloxyphenyl)-1-phenyl-1H-benzimidazole (C25H26N2O; 2) and 1-benzyl-2-(4-hexyloxyphenyl)-1H-benzimidazole (C26H28N2O; 3) were synthesized and their structures were ...
Daniil E. Smirnov +2 more
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Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast
Cells, 2021 The cytoskeleton microtubule consists of polymerized αβ-tubulin dimers and plays essential roles in many cellular events. Reagents that inhibit microtubule behaviors have been developed as antifungal, antiparasitic, and anticancer drugs.
Mamika Minagawa +3 more
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Pharmaceuticals, 2021 A significant number of the anti-inflammatory drugs currently in use are becoming obsolete. These are exceptionally hazardous for long-term use because of their possible unfavourable impacts.
Ravichandran Veerasamy +3 more
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Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines [PDF]
Molecular Diversity, 2012 AbstractA series of title compounds is synthesized by a strategy which involves Ugi four‐component condensation of the isonitrile (I) followed by TFA‐mediated deprotection and cyclization.
Gary S. Nichol +5 more
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Berichte der deutschen chemischen Gesellschaft, 1903 n ...
Fischer, O., Hess, W.
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Evaluation of the effects of some benzimidazole derivatives on germination parameters of wheat varieties [PDF]
Journal of Agricultural Sciences (Belgrade)This study aims to investigate the effect of some benzimidazole derivatives on the germination parameters of bread and durum wheat varieties. These derivatives contain both unsubstituted and substituted benzimidazole structures to determine the effect of
Külen Seda, Dincer Sebla
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