Results 1 to 10 of about 36,697 (193)
Results in Chemistry, 2023 Heterocyclic compounds are foundational in drug discovery, constituting the core structure of approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical aromatic heterocyclic system present in natural compounds, playing an ...
Neha D. Mahurkar +4 more
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Biologically Active Benzimidazole Hybrids as Cancer Therapeutics: Recent Advances [PDF]
PharmaceuticalsCancer is a highly significant medical concern, as it is the second most prevalent cause of mortality after cardiovascular diseases. It arises due to dysregulated cell cycle control, leading to a gradual decline in cellular differentiation and ...
Mohamed A. S. Badawy +4 more
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Monitoring of Benzimidazole Resistance in Botrytis cinerea Isolates from Strawberry in Korea and Development of Detection Method for Benzimidazole Resistance [PDF]
The Plant Pathology Journal, 2023 Botrytis cinerea is a major fungal plant pathogen that causes gray mold disease in strawberries, leading to a decrease in strawberry yield. While benzimidazole is widely used as a fungicide for controlling this disease, the increasing prevalence of ...
Geonwoo Kim +5 more
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Synthesis of ruthenium(II) carbonyl complexes with 2-monosubstituted and 1,2-disubstituted benzimidazoles [PDF]
Journal of the Serbian Chemical Society, 2009 The reaction of the polymeric carbonyl complex [RuCl2(CO)2]x with 2-monosubstituted and 1,2-disubstituted benzimidazoles and 1,4-bis(benzimi-dazol-2-yl)benzene (L9) in 2-methoxyethanol produces various coloured complexes of the formulae [Ru(CO)2Cl2(L)2 ...
GANGA NAIK KRISHNAMURTHY +1 more
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Synthesis and crystal structures of N-H, N-phenyl and N-benzyl-2-(4-hexyloxyphenyl)benzimidazoles
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compounds, 2-(4-hexyloxyphenyl)-1H-benzimidazole (C19H22N2O; 1), 2-(4-hexyloxyphenyl)-1-phenyl-1H-benzimidazole (C25H26N2O; 2) and 1-benzyl-2-(4-hexyloxyphenyl)-1H-benzimidazole (C26H28N2O; 3) were synthesized and their structures were ...
Daniil E. Smirnov +2 more
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Coumarin – benzimidazole hybrids: A review on diverse synthetic strategies
Results in Chemistry, 2022 Benzimidazole and coumarin are highly significant pharmacophores in medicinal chemistry due to their numerous and compelling biological activities. It has been found that combining two or more pharmacophores in a single moiety can improve the efficiency ...
C.G. Arya +6 more
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Benzimidazole and its derivatives: Recent Advances (2020–2022)
Results in Chemistry, 2023 Benzimidazoles are fused heterocyclic ring systems containing two nitrogen atoms. They have vital therapeutic significance in drug discovery. Many clinically approved drugs have been developed from benzimidazole, and these include liarozole and ...
Oluwakemi Ebenezer +3 more
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Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast
Cells, 2021 The cytoskeleton microtubule consists of polymerized αβ-tubulin dimers and plays essential roles in many cellular events. Reagents that inhibit microtubule behaviors have been developed as antifungal, antiparasitic, and anticancer drugs.
Mamika Minagawa +3 more
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Journal of Materials Research and Technology, 2022 In order to delay or solve the issue of metal material corrosion, six benimidazole derivativesmolecules namely, 2,6- bis (benzimidazole-2′-yl) pyridine (A), 2,5- bis (benzimidazole -2′-yl) pyridine (B), 2,4- bis (benzimidazole -2′-yl) pyridine (C), 2,3 ...
Jianwei Zhu +6 more
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Pharmaceuticals, 2021 A significant number of the anti-inflammatory drugs currently in use are becoming obsolete. These are exceptionally hazardous for long-term use because of their possible unfavourable impacts.
Ravichandran Veerasamy +3 more
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