Results 1 to 10 of about 11,134 (195)

A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives [PDF]

open access: yesFrontiers in Pharmacology, 2021
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole scaffolds are considerably prevalent.
Shejuti Rahman Brishty   +5 more
doaj   +2 more sources

Recent achievements in the synthesis of benzimidazole derivatives. [PDF]

open access: yesRSC Adv, 2023
This article gives a comprehensive review on the synthesis of benzimidazoles including reaction mechanisms and a brief description of biological application of benzimidazole derivatives by summarizing recent studies.
Chung NT, Dung VC, Duc DX.
europepmc   +3 more sources

Serious adverse events reported with benzimidazole derivatives: A disproportionality analysis from the World Health Organization's pharmacovigilance database. [PDF]

open access: yesPLoS Neglected Tropical Diseases
BackgroundBenzimidazole derivatives are widely used anthelmintic drugs, particularly in mass campaigns for intestinal parasitosis treatment. Despite their generally good safety profile, serious adverse reactions have been reported.
Pamella Modingam   +2 more
doaj   +2 more sources

Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases [PDF]

open access: hybridE-Journal of Chemistry, 2010
The ring system in which a benzene ring is fused to the 4,5-positions of imidazole is designated as benzimidazole. Condensations of 2-substituted benzimidazole derivatives were synthesized by different carboxylic acids using Mannich base and anti ...
B. Anil Reddy
doaj   +2 more sources

Benzimidazole Derivatives as Energetic Materials: A Theoretical Study. [PDF]

open access: yesMaterials (Basel), 2021
The explosive properties and stability of benzimidazole compounds are studied to determine the influence of substituents and their position. The results obtained reveal the conjugation of substituents as one of the crucial factors for the thermal stability of these compounds.
Sarlauskas J   +3 more
europepmc   +6 more sources

Antibacterial Activity of the Halogen- and Nitro Derivatives of Benzimidazole Against Bacillus Subtilis

open access: yesАнтибиотики и Химиотерапия, 2023
Background. Antibiotic resistance of bacteria is a serious concern for modern medicine. The search for new compounds with a pronounced antibacterial effect is an urgent task of pharmaceutical chemistry.
R. S. Begunov   +4 more
doaj   +1 more source

Antimicrobial Activity of Benzimidazoles Derivatives [PDF]

open access: yesInternational Journal of Management and Humanities, 2020
The anti-microbial action of benzimidazole of ampicillin, was examined in Vitro beneath a specific conditions, utilizing the disc diffusion method, against different gram-positive and gram-negative pathogenic microorganisms such as Bacillus cereus, Staphylococcus aureus Pseudomonas aeruginosa and Escherichia Coli. An arrangement of these compounds were
Bapatla Municipality, Ward women Protection Secretary, Bapatla, India.   +4 more
openaire   +2 more sources

In-silico ADME prediction and molecular docking study of novel benzimidazole-1,3,4-oxadiazole derivatives as CYP51 inhibitors for antimicrobial activity

open access: yesJournal of Applied Pharmaceutical Research, 2022
A class of innovative benzimidazole-1,3,4-Oxadiazole derivatives is a significant heterocyclic molecule for therapeutic development. In heterocyclic chemistry, the novel 1,3,4-Oxadiazole nucleus has a wide range of uses, including antibacterial ...
Shivanand Kolageri   +2 more
doaj   +1 more source

In Search of the Antimicrobial Potential of Benzimidazole Derivatives [PDF]

open access: yesPolish Journal of Microbiology, 2016
Abstract A broad series of 4,5,6,7-tetrahalogenated benzimidazoles and 4-(1H-benzimidazol-2-yl)-benzene-1,3-diol derivatives was tested against selected bacteria and fungi. For this study three plant pathogens Colletotrichum sp., Fusarium sp., and Sclerotinia sp., as well as Staphylococcus sp., Enterococcus sp., Escherichia sp ...
JANECZKO, MONIKA   +6 more
openaire   +5 more sources

Evaluation of the effects of some benzimidazole derivatives on germination parameters of wheat varieties [PDF]

open access: yesJournal of Agricultural Sciences (Belgrade)
This study aims to investigate the effect of some benzimidazole derivatives on the germination parameters of bread and durum wheat varieties. These derivatives contain both unsubstituted and substituted benzimidazole structures to determine the effect of
Külen Seda, Dincer Sebla
doaj   +1 more source

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