Results 1 to 10 of about 27,476 (269)

A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives [PDF]

Frontiers in Pharmacology, 2021
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole scaffolds are considerably prevalent.
Shejuti Rahman Brishty, Md. Jamal Hossain, Mayeen Uddin Khandaker, Mohammad Rashed Iqbal Faruque, Hamid Osman, S. M. Abdur Rahman   +5 more
doaj   +2 more sources

Serious adverse events reported with benzimidazole derivatives: A disproportionality analysis from the World Health Organization's pharmacovigilance database. [PDF]

PLoS Neglected Tropical Diseases
BackgroundBenzimidazole derivatives are widely used anthelmintic drugs, particularly in mass campaigns for intestinal parasitosis treatment. Despite their generally good safety profile, serious adverse reactions have been reported.
Pamella Modingam, Jean-Luc Faillie, Jérémy T Campillo   +2 more
doaj   +2 more sources

Corrosion inhibition performance of benzimidazole derivatives for protection of carbon steel in hydrochloric acid solution. [PDF]

RSC Adv
Timoudan N, Al-Gorair AS, El Foujji L, Warad I, Safi Z, Dikici B, Benhiba F, Qaiss AEK, Bouhfid R, Bentiss F, Al-Juaid SS, Abdallah M, Zarrouk A, Zarrouk A.   +13 more
europepmc   +3 more sources

2-(Cyanomethyl)benzimidazole Derivatives as 1,3-Dicarbonyl Analogues for a Kinetically Controlled Diastereo- and Enantioselective Mannich-Type Reaction Catalyzed by Chiral Phosphoric Acid. [PDF]

Org Lett
Ye H, Hou L, Takeda A, Sato T, Yadav J, Kikuchi J, Bao M, Terada M.   +7 more
europepmc   +2 more sources

Quinoline-imidazole/benzimidazole derivatives as dual-/multi-targeting hybrids inhibitors with anticancer and antimicrobial activity. [PDF]

Sci Rep, 2022
Diaconu D, Antoci V, Mangalagiu V, Amariucai-Mantu D, Mangalagiu II.   +4 more
europepmc   +3 more sources

Review- biological active benzimidazole derivatives

Results in Chemistry, 2021
In the field of Medicinal Chemistry, the uses of heterocyclic compounds increased day by day, because in many biological materials, heterocyclic compound is a part of its structure.
Balasaheb Pathare, Tanaji Bansode
doaj   +1 more source

Antibacterial Activity of the Halogen- and Nitro Derivatives of Benzimidazole Against Bacillus Subtilis

Антибиотики и Химиотерапия, 2023
Background. Antibiotic resistance of bacteria is a serious concern for modern medicine. The search for new compounds with a pronounced antibacterial effect is an urgent task of pharmaceutical chemistry.
R. S. Begunov, D. O. Egorov, A. V. Chetvertakova, L. I. Savina, A. A. Zubishina   +4 more
doaj   +1 more source

Benzimidazole derivatives as a new scaffold of anticancer agents: Synthesis, optical properties, crystal structure and DFT calculations. [PDF]

Heliyon
Zouaghi MO, Bensalah D, Hassen S, Arfaoui Y, Mansour L, Özdemir N, Bülbül H, Gurbuz N, Özdemir I, Hamdi N.   +9 more
europepmc   +3 more sources

In-silico ADME prediction and molecular docking study of novel benzimidazole-1,3,4-oxadiazole derivatives as CYP51 inhibitors for antimicrobial activity

Journal of Applied Pharmaceutical Research, 2022
A class of innovative benzimidazole-1,3,4-Oxadiazole derivatives is a significant heterocyclic molecule for therapeutic development. In heterocyclic chemistry, the novel 1,3,4-Oxadiazole nucleus has a wide range of uses, including antibacterial ...
Shivanand Kolageri, S Hemanth, Mahesh Parit   +2 more
doaj   +1 more source

Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine

Acta Pharmaceutica Sinica B, 2023
Cancer is the second leading cause of mortality globally which remains a continuing threat to human health today. Drug insensitivity and resistance are critical hurdles in cancer treatment; therefore, the development of new entities targeting malignant ...
Yeuan Ting Lee, Yi Jer Tan, Chern Ein Oon   +2 more
doaj   +1 more source