Results 141 to 150 of about 25,772 (306)

BubR1 Insufficiency Drives Transcriptomic Alterations and Pathology Associated With Cardiac Aging and Heart Failure

open access: yesAging Cell, EarlyView.
Transcriptomic and cellular analyses of BubR1 hypomorphic hearts reveal disruptions in key pathways and upregulation of markers linked to impaired cardiac structure and function. Comparative transcriptomic analysis shows that BubR1 insufficiency mirrors changes seen in aged and failing hearts. A key finding of this study is that BubR1 levels decline in
Renju Pun   +13 more
wiley   +1 more source

Synthesis of ruthenium(III) complexes with benzimidazole derivatives [PDF]

open access: green, 2003
P. C. Vyas   +3 more
openalex   +1 more source

Thermal Fragmentation and Rearrangement of 3-phenyl-4-aryl-5-phenylimino-1,2,4-oxadiazoline Derivatives [PDF]

open access: yes, 2009
Thermal fragmentation of 3-phenyl-4-aryl-5-phenylimino-1,2,4-oxadiazolines I and II (Ar= Ph, p-tolyl) in a sealed tube under nitrogen gives rise to benzonitrile, arylamines, anilides, phenols, arylureas, and benzimidazole derivatives.
Gaber, Abd El-Aal M., Nahas, Nariman
core  

Structure‐based discovery of thiamine uptake inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel   +2 more
wiley   +1 more source

Synthesis and Antioxidant Properties of Novel Benzimidazole Derivatives [PDF]

open access: bronze, 2004
Gülgün Ayhan‐Kılcıgil   +4 more
openalex   +1 more source

Trends in novel opioid use and detections in exposures and police drug seizures in New South Wales

open access: yesDrug and Alcohol Review, EarlyView.
Abstract Introduction Novel opioids, including non‐medical and non‐opium‐based opioids such as fentanyl analogues and nitazenes, pose a significant risk of harm due to their high potency. There is little published data on novel opioid detections and harms in Australia, yet they are implicated in multiple deaths.
Janette L. Smith   +7 more
wiley   +1 more source

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