Facile Synthesis, Characterization and Antimicrobial Activity of 2-Alkanamino Benzimidazole Derivatives [PDF]
Benzimidazole derivatives are known to represent a class of medicinally important compounds which are extensively used in drug design and catalysis. A series of 2-substituted benzimidazole derivatives 10a-i was herein synthesized from the reaction of o ...
Aderohunmu, D. V.+4 more
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New properties of a bioinspired pyridine benzimidazole compound as a novel differential staining agent for endoplasmic reticulum and Golgi apparatus in fluorescence live cell imaging [PDF]
Indexación: Scopus.In this study, we explored new properties of the bioinspired pyridine benzimidazole compound B2 (2,4-di-tert-butyl-6-(3H-imidazo[4,5-c]pyridine-2-yl)phenol) regarding its potential use as a differential biomarker.
Alexander Carreño+10 more
core +12 more sources
Review- biological active benzimidazole derivatives
In the field of Medicinal Chemistry, the uses of heterocyclic compounds increased day by day, because in many biological materials, heterocyclic compound is a part of its structure.
Balasaheb Pathare, Tanaji Bansode
doaj
Benzimidazole scaffolds as promising antiproliferative agents: a review
Cancer is one of the most serious medical problem and second leading cause of death in the world, characterized by a deregulation of the cell cycle which mainly results in a progressive loss of cellular differentiation and uncontrolled cellular growth ...
Sumit Tahlan+3 more
doaj +1 more source
Aminoacids Derivatives with a Potential Anti-inflammatory Activity
The paper presents the synthesis of benzimidazole derivatives starting from asparagic acid. The reaction products were analysed from physical and chemical point of view and their biological activity (acute toxicity, anti-inflammatory activity and gastric
V. Sunel+4 more
doaj +1 more source
Synthesis and Characterization of Novel Pyrimido [1,2-a] benzimidazole and its Derivatives
A few pyrimido[1,2-a] benzimidazole derivatives had been synthesized, derived from 4-amino-2-(4-chloro or bromophenyl) -1,2-dihydropyrimido[1,2-a] benzimidazole-3-carbonitrile (4 or 5) is made through one pot three components condensation reaction of 1H ...
Fadhel R. Hafedh+2 more
doaj +1 more source
Benzimidazole Derivatives as Antidiabetic Agents [PDF]
Benzimidazoleis an important pharmacophore which was included in several biologically active compounds resulted in the development of several classes of drugs. This review discusses the synthesis of benzimidazole derivatives as a target agents for antidiabeticby different mechanism such as peroxisome proliferator – activated receptor α transcriptional ...
Rashedy+2 more
openaire +1 more source
Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells [PDF]
The small molecule 4-hydroxy-3-methoxybenzaldehyde (5,6,7,8-tetrahydro[1]benzothieno[2,3- d]pyrimidin-4-yl)hydrazone (Exo2) stimulates morphological changes at the mammalian Golgi and trans-Golgi network that are virtually indistinguishable from those ...
Barr+67 more
core +1 more source
Zinc 2-((2-(benzoimidazol-2-yl)quinolin-8-ylimino)methyl)phenolates : synthesis, characterization and photoluminescence behavior [PDF]
A series of 2-(2-(1H-benzoimidazol-2-yl)quinolin-8-yliminomethyl)phenol derivatives and their zinc complexes (C1 – C5) were synthesized and fully characterized.
Li, Longlong+6 more
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Herein, an efficient one-pot synthesis is described, of substituted benzimidazole derivatives (3a-j) from a condensation of various o-phenylenediamine (1a-j) aromatic aldehyde (2a-j) using ZnFe2O4 as a nano-catalyst under ultrasonic irradiation ...
Dhanraj Kamble+5 more
doaj +1 more source