Results 11 to 20 of about 17,710 (239)
Synthesis and characterization of novel benzimidazole embedded 1,3,5-trisubstituted pyrazolines as antimicrobial agents [PDF]
J. Med. Chem. 51 (2008) 5243, Pharma Chem. 8 (2016) 425, RSC Adv.
6 (2016) 8303, Int. J. Mol. Sci. 13 (2012)16472, J. Chem. Res. 40 (2016) 228, 2020 Efficient syntheses of some new substituted pyrazoline derivatives linked to substituted benzimidazole scaffold were performed by multistep reaction sequences. All the synthesized compounds were characterized using elemental analysis and spectral studies (IR, 1D/2D NMR techniques and mass spectrometry). The synthesized compounds were screened for their
arxiv +1 more source
Frontiers in Microbiology, 2014 Cobamides are a family of enzyme cofactors that include vitamin B12 (cobalamin) and are produced solely by prokaryotes. Structural variability in the lower axial ligand has been observed in cobamides produced by diverse organisms. Of the three classes of
Terence S Crofts +3 more
doaj +1 more source
α-Chymotrypsin-catalyzed synthesis of 2-substituted benzimidazole through retro-Claisen reaction
Green Chemistry Letters and Reviews, 2018 Benzimidazoles are important components of pharmaceutical compounds owing to their promising bioactivities. The green, safe, and efficient synthesis of benzimidazoles has always been one of the hot topics for chemical workers.
Lian-Sheng Liu +5 more
doaj +1 more source
Kinetic Monte Carlo simulations of proton conductivity [PDF]
Phys. Rev. E 90, 012135 (2014), 2014 The kinetic Monte Carlo method is used to model the dynamic properties of proton diffusion in anhydrous proton conductors. The results have been discussed with reference to a two-step process called the Grotthuss mechanism. There is a widespread belief that this mechanism is responsible for fast proton mobility.
arxiv +1 more source
Veterinary Research, 2020 The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g.
Pavlína Kellerová +8 more
doaj +1 more source
The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation
Molecules, 2022 The benzimidazole ring of the heterocyclic pharmacophores is one of the most widespread and studied systems in nature. The benzimidazole derivative synthesis study is a crucial point for the development of a clinically available benzimidazole-based drug.
Monica Nardi +4 more
doaj +1 more source
Numerical modeling of the heterocycle intercalated proton-conducting polymers at various mole ratios [PDF]
Solid State Ionics 272, 166-169, 2015, 2014 The kinetic Monte Carlo simulations are employed to study the proton conductivity for anhydrous heterocyclic based polymers. The proton transport is based on a two-step process called the Grotthuss mechanism. In the referring system the proton concentration depends on the relative molar ratio, $x$, of the benzimidazole and the polystyrene sulfonic acid.
arxiv +1 more source
Egyptian Journal of Petroleum, 2017 Hydrogen bonded interaction and synergistic effect on the corrosion protection properties of alkyl benzimidazoles and semicarbazide pair on mild steel in hydrochloric acid at 303, 308 and 313 K have been studied by polarization, electrochemical impedance
K. Ramya +3 more
doaj +1 more source
Molecules, 2023 The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors.
M. Akiful Haque +11 more
doaj +1 more source
Narrowband terahertz radiation by an impulsive stimulated Raman scattering in an above-room-temperature organic ferroelectric benzimidazole [PDF]
Phys. Rev. A 98, 013843 (2018), 2018 We observe a terahertz radiation from a hydrogen-bonded organic molecular ferroelectric 5,6-dichloro-2-methylbenzimidazole excited by a femtosecond laser pulse at room temperature. The emitted terahertz wave consists of three oscillatory components, the frequencies of which agree with those of Raman- and infrared-active phonon modes. This suggests that
arxiv +1 more source