Results 201 to 210 of about 40,476 (314)
ChemMedChem, Volume 20, Issue 15, August 2, 2025.The work presents details of the efforts to design and characterize novel D4 inhibitors. A new 4,4‐difluoropiperidine ether series that confers improved potency and selectivity for D4 versus the other dopamine receptor subtypes is identified. Extensive structure‐activity relationship around this privileged group identifies the key structural changes to
Saeedeh Saeedi +3 more
wiley +1 more source
Synthesis and SARs of benzimidazoles: insights into antimicrobial innovation (2018-2024). [PDF]
RSC AdvIbrahim AA +4 more
europepmc +1 more source
Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley +1 more source
Liquid Coordination Polymers with Anhydrous Proton Conductivity
Angewandte Chemie, Volume 137, Issue 30, July 21, 2025.Functional liquid coordination polymers near ambient conditions are prepared by introducing H3PO4 as a network modifier. This process disrupts extended coordination networks, producing a stable liquid. Liquid properties are controlled by tuning the ratio of network modifiers, resulting in anhydrous proton conductivity up to 27 mS cm−1 at 353 K and ...
Nattapol Ma +3 more
wiley +2 more sources
Benzimidazole(s): synthons, bioactive lead structures, total synthesis, and the profiling of major bioactive categories. [PDF]
RSC AdvAroua LM +8 more
europepmc +1 more source
Injectable benzimidazole anthelmintics effective against liver flukes, tapeworms, lungworms and gastrointestinal roundworms [PDF]
, 1978 Larry R. Cruthers +5 more
openalex +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.ABSTRACT Protonitazene (PNZ) is a synthetic opioid emerging in Europe, Australia, North America and South America with a rapidly increasing number of intoxications. To describe PNZ's pharmacological characteristics, detection methods and the clinical presentation and management of PNZ intoxications, the PubMed database was searched for original ...
Jake Verbeek, David J. Brinkman
wiley +1 more source
Angewandte Chemie, Volume 137, Issue 30, July 21, 2025.Structural shaping of a highly reactive chiral Mn‐oxo species translates into exceptionally enantioselective C─H oxidation catalyst of cyclohexyl 1,3‐meso diethers (up to >99% ee) leading to polyfunctionalized cyclohexanes. Abstract Chiral polyoxygenated cyclohexanes are valuable constituents of biologically relevant products.
Andrea Palone +7 more
wiley +2 more sources