Long-term consequences of benzodiazepine-induced neurological dysfunction: A survey
PLoS ONE, 2023 Background Acute benzodiazepine withdrawal has been described, but literature regarding the benzodiazepine-induced neurological injury that may result in enduring symptoms and life consequences is scant.
Alexis D. Ritvo +5 more
doaj +3 more sources
Health Expectations, 2022 Introduction Long‐term benzodiazepine receptor agonist (BZRA) use persists in healthcare settings worldwide and poses risks of patient harm. Objective This study aimed to develop an intervention to support discontinuation of long‐term BZRA use among ...
Tom Lynch +8 more
doaj +1 more source
Comparison of Nitrous Oxide-Oxygen as Inhalation Agent, Midazolam, Ketamine alone and in Combination as Oral Sedative Agents for In-office Paediatric PatientsA Randomised Control Trial [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: In-office pharmacological sedation techniques are best applied to manage an extremely fearful preschooler, especially during primary dentition or a child’s early mixed dentition period.
MONIKA NAGPAL +4 more
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GABAA receptor subtypes and benzodiazepine use, misuse, and abuse
Frontiers in Psychiatry, 2023 Benzodiazepines have been in use for over half a century. While they remain highly prescribed, their unfavorable side-effect profile and abuse liability motivated a search for alternatives.
Elif Engin, Elif Engin
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Exploring trends in benzodiazepine-positive fatal drug overdoses in Tennessee, 2019–2021
Annals of Medicine, 2023 Background Benzodiazepine-positive overdoses increased between 2019 and 2021 in Tennessee. We sought to determine the changes in the number and characteristics of prescription and illicit benzodiazepine-positive fatal drug overdoses during this period ...
Jenna Moses +2 more
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A review on the chemistry and pharmacological properties of benzodiazepine motifs in drug design
Arab Journal of Basic and Applied Sciences, 2022 Benzodiazepines are an important class of heterocyclic compounds in organic chemistry. They are known for their diverse physicochemical and biological properties.
Olayinka O. Tolu-Bolaji +3 more
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Epidemiologic assessment of benzodiazepine exposure among suicide deaths in Colorado, 2015–2017
BMC Public Health, 2020 Background Suicide rates have been climbing in the U.S., particularly in Rocky Mountain states such as Colorado. Benzodiazepines have been linked with suicidal ideation, but there have been few population level assessments of this link.
Tista Ghosh +6 more
doaj +1 more source
Is Zolpidem Associated with Increased Risk of Fractures in the Elderly with Sleep Disorders? A Nationwide Case Cross-Over Study in Taiwan. [PDF]
PLoS ONE, 2015 We conducted a study using a case-crossover design to clarify the risk of acute effects of zolpidem and benzodiazepine on all-sites of fractures in the elderly.Case-crossover design.Elderly enrollees (n = 6010) in Taiwan's National Health Insurance ...
Yih-Jing Tang +11 more
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Frontiers in Aging Neuroscience, 2021 Background: Gamma-aminobutyric acid (GABA) type A receptors are positively allosterically modulated by benzodiazepine binding, leading to a potentiated response to GABA.
Tomonori Furukawa +8 more
doaj +1 more source
Withdrawal-induced delirium associated with a benzodiazepine switch: a case report
Journal of Medical Case Reports, 2011 Introduction Introduced in the early 1960s, diazepam remains among the most frequently prescribed benzodiazepine-type sedatives and hypnotics. Patients with chronic use of short-acting benzodiazepines are frequently switched to diazepam because the ...
Bosshart Herbert
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