Results 21 to 30 of about 138,894 (338)
Predicting benzodiazepine prescriptions: A proof-of-concept machine learning approach
Frontiers in Psychiatry, 2023 IntroductionBenzodiazepines are the most commonly prescribed psychotropic medications, but they may place users at risk of serious adverse effects. Developing a method to predict benzodiazepine prescriptions could assist in prevention efforts.MethodsThe ...
Kerry L. Kinney +11 more
doaj +1 more source
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
core +1 more source
TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control [PDF]
, 2014 The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane (OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits mitochondrial autophagy downstream of the PINK1-PARK2 pathway, preventing essential ...
Anholt R +22 more
core +2 more sources
BMC Complementary and Alternative Medicine, 2017 Background Conventional approaches for benzodiazepine tapering have their limitations. Anecdotal studies have shown that acupuncture is a potential treatment for facilitating successful benzodiazepine tapering.
Wing-Fai Yeung +9 more
doaj +1 more source
Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]
, 2019 BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A +7 more
core +1 more source
Treatment strategy for insomnia disorder: Japanese expert consensus
Frontiers in Psychiatry, 2023 PurposeThere is a lack of evidence regarding answers for clinical questions about treating insomnia disorder. This study aimed to answer the following clinical questions: (1) how to use each hypnotic and non-pharmacological treatment differently ...
Yoshikazu Takaesu +24 more
doaj +1 more source
Treatment of pediatric convulsive status epilepticus
Frontiers in Neurology, 2023 Status epilepticus is one of the most common life-threatening neurological emergencies in childhood with the highest incidence in the first 5 years of life and high mortality and morbidity rates.
Lena-Luise Becker +11 more
doaj +1 more source
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]
, 2017 A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa +3 more
core +1 more source
Increasing Benzodiazepine Prescriptions and Overdose Mortality in the United States, 1996-2013.
American Journal of Public Health, 2016 OBJECTIVES To describe trends in benzodiazepine prescriptions and overdose mortality involving benzodiazepines among US adults. METHODS We examined data from the Medical Expenditure Panel Survey and multiple-cause-of-death data from the Centers for ...
M. Bachhuber +3 more
semanticscholar +1 more source
Epilepsia Open, EarlyView., 2023 Abstract Growing concerns over rigor and reproducibility of preclinical studies, including consistency across laboratories and translation to clinical populations, have triggered efforts to harmonize methodologies. This includes the first set of preclinical common data elements (CDEs) for epilepsy research studies, as well as Case Report Forms (CRFs ...
Lisa Coles +9 more
wiley +1 more source