Results 71 to 80 of about 138,894 (338)
Robust chemical routes towards valuable bioactive entities such as riboflavines, quinoxalinones and benzodiazepines are described. These make use of modern flow hydrogenation protocols enabling the chemoselective reduction of nitro group containing ...
Marcus Baumann+5 more
doaj +1 more source
Abstract Aims The perspectives of patients and healthcare professionals regarding deprescribing in surgical wards within hospital settings are unknown. The aim of this study was to explore current practices, attitudes and the enablers and barriers to deprescribing in hospital for older surgical inpatients from the perspectives of doctors, pharmacists ...
Bonnie M. Liu+5 more
wiley +1 more source
In this report, we present cross-sectional and longitudinal findings from single-voxel MEGA-PRESS MRS of GABA as well as Glu, and Glu + glutamine (Glx) concentrations in the ACC of treatment-seeking alcohol-dependent patients (ADPs) during detoxification
Guoying Wang+8 more
doaj +1 more source
Pregabalin: a range of misuse-related unanswered questions [PDF]
© 2019 The Authors.
Chiappini, Stephania, Schifano, Fabrizio
core +2 more sources
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière+13 more
wiley +1 more source
ObjectivesChronic use of benzodiazepines and zolpidem (BDZ/Z-drugs) leads to dependency, cognitive impairment, and falls. Although controlled-release melatonin (Melatonin CR) may be an alternative, a switch in clinical settings has proven difficult.
Ji Hyun An+11 more
doaj +1 more source
Five traits of personality in benzodiazepine-dependent patients with bipolar disorder
Introduction Benzodiazepines (BZD) are frequently prescribed to patients with bipolar disorder. The use of this medication can become problematic in some cases or even lead to dependence mainly in patients with personality disorders.
N. Charfi+8 more
doaj +1 more source
Benzodiazepine use, misuse, and abuse: A review
Benzodiazepine (BZD) abuse has reached epidemic levels and results in poor outcomes, particularly when combined with concomitant central nervous system depressants. BZDs are abused most commonly in combination with opioids and alcohol.
Allison Schmitz
semanticscholar +1 more source
The problem of propranolol poisoning
Aims Propranolol is licensed in the UK and elsewhere to relieve symptoms of anxiety. In overdose, propranolol poisoning can be serious, difficult to treat and potentially fatal. This paper describes cases of intentional propranolol overdose reported to the UK National Poisons Information Service in order to raise awareness of the risk of harm following
Hayley Williams+8 more
wiley +1 more source
Benzodiazepine maintenance for alcohol dependence: A case series
Alcohol addiction is a chronic relapsing syndrome. Benzodiazepines remain as the mainstay for detoxification, taking care of the acute withdrawal syndrome. There is fear of dependence and abuse of benzodiazepines on prolonged use.
Shivanand Kattimani+2 more
doaj +1 more source