Results 71 to 80 of about 123,980 (206)
Canadian Medical Association Journal, 2017 BACKGROUND: Knowledge regarding whether benzodiazepines and similarly acting non-benzodiazepines (Z-drugs) are associated with an increased risk of pneumonia among older adults is lacking.
H. Taipale +7 more
semanticscholar +1 more source
Benzodiazepine abuse among the elderly
Journal of Geriatric Mental Health, 2016 Benzodiazepines belong to the hypnotic-sedative class of drugs which have anxiolytic, sedative, and hypnotic properties. These drugs have been in clinical use for at least half a century.
Shalini Singh, Siddharth Sarkar
doaj +1 more source
Association between Benzodiazepine Use and Dementia: A Meta-Analysis
PLoS ONE, 2015 Background The association between long-term benzodiazepine use and risk of dementia remains controversial. Therefore, current study aimed to quantify this association, and to explore a potential dose–response pattern.
Guochao Zhong +3 more
semanticscholar +1 more source
Addressing the Issue of Chronic, Inappropriate Benzodiazepine Use: How Can Pharmacists Play a Role?
Pharmacy, 2013 Prescribing guidelines do not recommend the long-term use of benzodiazepines since their effectiveness with chronic use is out-weighed by risks including dependence, memory and cognitive impairment, hip fractures and traffic accidents.
Helen C. Gallagher
doaj +1 more source
Nature Communications, 2015 Agonists at the benzodiazepine-binding site of GABAA receptors (BDZs) enhance synaptic inhibition through four subtypes (α1, α2, α3 and α5) of GABAA receptors (GABAAR).
William T. Ralvenius +4 more
semanticscholar +1 more source
Associations between pain-management treatments and opioid use disorder risk among Medicaid patients [PDF]
arXivIntroduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typically implemented together, confounding their independent effects. We estimated the extent to which pain-management strategies were associated with risk of incident opioid use
arxiv
Sleep, 2015 STUDY OBJECTIVES Insomnia is prevalent in patients with chronic obstructive pulmonary disease (COPD), and benzodiazepine receptor agonists (BZRAs) are the most commonly used drugs despite their adverse effects on respiratory function.
Su-Jung Chen +7 more
semanticscholar +1 more source
Nature's Brewery to Bedtime: The Role of Hops in GABAA Receptor Modulation and Sleep Promotion [PDF]
Doctoral Dissertation University of Turku. ISBN: 978-951-29-9577-6
(2023)Insomnia often requires pharmacological interventions, with benzodiazepines and Z-drugs enhancing GABA's inhibitory effects by stabilizing GABAA receptor chloride ion channels. Prolonged use, however, raises dependency and cognitive concerns. Humulus lupulus (hops) is gaining attention as a natural relaxant and sleep aid, potentially modulating GABAA ...
arxiv
Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users.
Cochrane Database of Systematic Reviews, 2015 BACKGROUND Prolonged treatment with benzodiazepines is common practice despite clinical recommendations of short-term use. Benzodiazepines are used by approximately 4% of the general population, with increased prevalence in psychiatric populations and ...
L. Baandrup +5 more
semanticscholar +1 more source