Results 241 to 250 of about 146,798 (343)

Opioid-Induced Myoclonus During Premedication in Two Dogs With Hydrocephalus Proactively Managed With Antiepileptic Medications. [PDF]

Vet Med Sci
Nam C, Lee I, Son WG.
europepmc   +1 more source

Validation of a transdiagnostic measure of fears of recurrence and progression about mental health conditions

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Fears of recurrence and progression (FORP) in people with mental health conditions are understudied despite predicting poorer psychological outcomes and increased rates of relapse. However, there are no well‐validated questionnaires that assess FORP in people with non‐psychotic conditions.
Daelin Coutts‐Bain, Louise Sharpe, Caroline Hunt   +2 more
wiley   +1 more source

A qualitative study of benzodiazepine/z-drug and opioid co-use patterns and overdose risk. [PDF]

Harm Reduct J
Family HE, Vojt G, Poulter H, Bailey CP, Abdala Sheikh AP, Cavallo D, Karimi S, Booth N, Da Silva P, Aitken L, Stewart S, Hickman M, Henderson G, Scott J, Kesten JM.   +14 more
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Successful Treatment of Paradoxical Vocal Cord Motion with Sub-dissociative Dose Ketamine: Case Report. [PDF]

Clin Pract Cases Emerg Med
Cameron-Burr K, Terry-Kantor E, Wilson T.   +2 more
europepmc   +1 more source

Drug use, impaired driving and traffic accidents [PDF]

, 2008
Griffiths, Paul, Hughes, Brendan, Lopez, Dominique, Raes, Elke, Van den Neste, Thomas, Verstraete, Alain   +5 more
core   +1 more source

Benzodiazepines on trial

BMJ, 1984
Michael C Gerald, Inayat Khan
openaire   +4 more sources

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Association Between Polygenic Risk Scores and Treatment Response to Antidepressants, Benzodiazepines, and Antihistamines in Anxiety and Depression. [PDF]

Biol Psychiatry Glob Open Sci
Markant A, Tabrizi F, Grönvall H, Speed D, Åhs F.   +4 more
europepmc   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades, Marcella Bassetto, Marius C. Staiculescu, Gayathri Swaminath, Samuel J. Fountain   +4 more
wiley   +1 more source