Results 61 to 70 of about 211,779 (381)

Influence of glutamatergic and GABAergic neurotransmission on obstructive sleep apnea

Frontiers in Neuroscience, 2023
Glutamate and γ-aminobutyric acid (GABA) are the two main neurotransmitters in the human brain. The balance between their excitatory and inhibitory functions is crucial for maintaining the brain’s physiological functions.
Piotr Kaczmarski, Marcin Sochal, Dominik Strzelecki, Piotr Białasiewicz, Agata Gabryelska   +4 more
doaj   +1 more source

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, EarlyView.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Social Listening of Benzodiazepines Abuse and Misuse

Emerging Trends in Drugs, Addictions, and Health
Introduction: Benzodiazepines are Class C drugs that can act as anxiolytics, hypnotics, sedatives, and muscle relaxants. Over the decade, benzodiazepine misuse has proliferated with increasing numbers of newly emerging benzodiazepines.
A. Guirguis
doaj   +1 more source

Benzodiazepine abuse among the elderly

Journal of Geriatric Mental Health, 2016
Benzodiazepines belong to the hypnotic-sedative class of drugs which have anxiolytic, sedative, and hypnotic properties. These drugs have been in clinical use for at least half a century.
Shalini Singh, Siddharth Sarkar
doaj   +1 more source

Prescription Trends in Complex Regional Pain Syndrome: A Retrospective Case–Control Study

Brain Sciences, 2023
Objective: The objective of this study was to evaluate discrepancies in prescription trends for analgesic medications in complex regional pain syndrome (CRPS) patients based on recommendations in the literature.
Suzanna Shermon, Kimberly M. Fazio, Richard Shim, Alaa Abd-Elsayed, Chong H. Kim   +4 more
doaj   +1 more source

The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective [PDF]

, 2019
© 2019 Orsolini, Chiappini, Papanti, De Berardis, Corkery and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania, Corkery, John Martin, De Berardis, Domenico, Orsolini, Laura, Papanti, Duccio, Schifano, Fabrizio   +5 more
core   +2 more sources

Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database

British Journal of Clinical Pharmacology, EarlyView.
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐threatening psychiatric events in some individuals.
Amy G. McNeilage, Ali Gholamrezaei, Bridin Murnion, Suzanne Nielsen, Claire E. Ashton‐James   +4 more
wiley   +1 more source

The effect of triazolam premedication on anxiety, sedation, and amnesia in general anesthesia [PDF]

Korean Journal of Anesthesiology, 2017
BackgroundBenzodiazepines have been used preoperatively as part of an anesthesia regimen to attenuate the anxiety of patients. In this study, we aimed to examine the effect of oral triazolam, a short-acting benzodiazepine, on anxiety, sedation, and ...
Taehee Pyeon, Shiyoung Chung, Injae Kim, Seongheon Lee, Seongwook Jeong   +4 more
doaj   +1 more source

Évaluation de la prescription et de l’utilisation des benzodiazépines dans la ville de Sidi Bel-Abbès

Journal de la Faculté de Médecine d'Oran, 2022
Introduction-A high consumption of benzodiazepines (BZDs) has been noticed sometimes outside the rules of prescription recommendations, which makes their consumption a major public health problem.
Derouicha Matmour, Mounia Medjeber, Yassine Merad   +2 more
doaj   +1 more source

Comparative analysis of the characteristics and trends of adverse drug reaction reports from patients in Japan and the Japanese Adverse Drug Event Report database

British Journal of Clinical Pharmacology, EarlyView.
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya, Ryohkan Funakoshi, Koichi Masuyama, Nariyasu Mano, Satoko Hori, Taku Obara   +5 more
wiley   +1 more source