Benzodiazepine abuse among the elderly
Journal of Geriatric Mental Health, 2016 Benzodiazepines belong to the hypnotic-sedative class of drugs which have anxiolytic, sedative, and hypnotic properties. These drugs have been in clinical use for at least half a century.
Shalini Singh, Siddharth Sarkar
doaj +1 more source
Trends in long-term prescribing of dependence forming medicines [PDF]
, 2019 Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S. +3 more
core
Former heroin-dependent alcohol use disorder patients. prevalence, addiction history and clinical features [PDF]
, 2015 Aims: To examine the prevalence of former heroin dependence (FHA) in Alcohol Use Disorder (AUD) patients; to compare the clinical characteristics of FHA-AUD patients versus AUD patients without any past use of heroin at alcohol treatment entry; to ...
Ceccanti, Mauro +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi +4 more
wiley +1 more source
Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]
, 2019 BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A +7 more
core +1 more source
Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core
Asian Journal of Organic Chemistry, EarlyView.An efficient method to develop novel dihydropyrido[3,2‐e][1,3]selenazines iminium salts. A comparative study of the key reagent selenourea towards thiourea and urea was carried out to assess the contribution of chalcogen to the pathway. DFT (density functional theory) calculations have predicted the optimized minimum energy structure for the hybrid ...
Reinier Lemos +6 more
wiley +1 more source
Reducing Benzodiazepine Use for the Treatment of Insomnia and Supporting Nonpharmacological Therapies [PDF]
, 2019 Most medical organizations recommend against the use of benzodiazepine use for the treatment of insomnia, especially in the elderly. However, the percentage of the adult population on benzos increase with age: 7.5% in adults ages 51-64; 9% in adults over
Pyon, UnChan
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Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life [PDF]
, 2003 Background: Older adults are the main recipients of repeat prescriptions for benzodiazepine (BZD) hypnotics. BZDs can impair cognitive function and may not aid sleep when taken continuously for years.
Collins, R. +5 more
core +1 more source
Pharmacotherapy, 2018 The use of benzodiazepines and the development of dementia is controversial, with studies indicating that benzodiazepines could be either a protective factor or a risk factor for dementia, or no association may exist between the two. Our objective was to
R. Lucchetta +2 more
semanticscholar +1 more source
Trends in gabapentinoid prescribing: A nationwide Danish drug utilization study
British Journal of Clinical Pharmacology, EarlyView.Aims Pregabalin and gabapentin are increasingly used for pain and other conditions. Concerns exist about overuse as well as potential misuse and abuse. To guide rational prescribing practices, we provide detailed nationwide data on the use of gabapentinoids in Denmark.
Anton Pottegård +7 more
wiley +1 more source