The synthesis and energy barriers to ring inversion of triazolo[4,3-d][1,4]benzodiazepinones
M.S. Puar, P.C. Wade, B.R. Vogt
core +1 more source
ChemInform Abstract: Studies Related to Alkylations of Enolate Anions of 1,4- Benzodiazepinones.
R. I. FRYER, R. B. UPASANI, J. C. PINTO
core +1 more source
Stereoselective [4+3]-Cycloaddition of 2-Amino-β-nitrostyrenes with Azaoxyallyl Cations to Access Functionalized 1,4-Benzodiazepin-3-ones. [PDF]
Kim Y, Kim SG.
europepmc +1 more source
Asymmetric Ir-catalyzed hydrogenation of 1,5-benzodiazepinones using mixtures of ligands
S. E. Lyubimov +2 more
core +1 more source
Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms. [PDF]
Osbelt L +23 more
europepmc +1 more source
Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines
Highly enantioselective Ir-catalyzed hydrogenation of seven-membered cyclic imines of benzodiazepinones and benzodiazepines was achieved with up to 96% ee. This method provides a direct access to synthesize a range of chiral cyclic amines existing in numerous important natural products and clinical drugs.
Kai Gao, Chang-Bin Yu, Qing-An Chen
exaly +4 more sources
First Highly Enantioselective Synthesis of Benzodiazepinones by Catalytic Hydrogenation
AbstractThe first catalytic enantioselective synthesis of benzodiazepinones employing an efficient hydrogenation protocol has been developed. The corresponding products are obtained in good yields, with excellent enantioselectivities and broad functional group tolerance.
Magnus Rueping +2 more
exaly +3 more sources
Related searches:
A new route to 1H-1,5-benzodiazepinones
Journal of the Chemical Society Chemical Communications, 1981Dimethyl allene-1,3-dicarboxylates react with o-phenylenediamine to give 1H-1, 5-benzodiazepinones and not benzimidazoles; the transient enamine intermediate shows preference for a 7-exo-trig ring closure.
Feodor Scheinmann
exaly +3 more sources

