Results 111 to 120 of about 607 (146)

Attempted synthesis of 2,4‐ and 1,3‐benzodiazepinones

Journal of Heterocyclic Chemistry, 1975
AbstractThe cyclodehydration reaction performed upon α‐acylamino carboxamides is known to constitute a facile synthetic approach to five‐membered heterocyclic systems. Attempts to prepare 2,4‐ and 1,3‐benzodiazepinone derivatives (VI, XIX) of potential C.N.S. Activity using such methods, proved unsuccessful. A new triazine system (X) which was prepared
Uri Golik, William Taub
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ChemInform Abstract: Synthesis and Reaction of Dihydrofuro(3,4‐b)(1,5)benzodiazepinones and Dihydropyrrolo(3,4‐b)(1,5)benzodiazepinones.

ChemInform, 1987
AbstractThe benzodiazepinones (IV) are obtained by acylation and subsequent cyclization of the diamines (Ia) and (Ib).
K. MATSUO, S. TAKADA, J. INOUE, K. TANAKA   +3 more
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One Pot Solvent-Free Synthesis of Benzodiazepinones Catalyzed by CuI

Chinese Journal of Organic Chemistry, 2017
Qiong Xiao, Qingyang Zhang, Dali Yin, Xiaojian Wang   +3 more
exaly   +2 more sources

Auranthine, a new benzodiazepinone metabolite of Penicillium aurantiogriseum

Journal of the Chemical Society, Perkin Transactions 1, 1986
A novel metabolite, auranthine, has been isolated from sporing cultures of Penicillium aurantiogriseum and its structure, 6,7,7a,8-tetrahydroquinazolino[3′,2′:1,6]pyrido[2,3-b][1,4]benzodiazepine-9,16-dione comprising anthranilate and glutamine moieties, has been elucidated from spectral evidence and biosynthetic reasoning.
Stephanie E. Yeulet, Peter G. Mantle, John N. Bilton, Henry S. Rzepa, Richard N. Sheppard   +4 more
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Direct liquid chromatographic separation of benzodiazepinone enantiomers

Journal of Chromatography A, 1984
Abstract The enantiomers of 46 3-substituted 5-phenyl-1,3-dihydro(2H)1,4-benzodiazepin-2-ones, diazepam (Valium®) analogues, have been chromatographically separated on chiral stationary phases derived from (R)-phenyl-glycine or (S)-leucine. Both analytical and preparative scale separations have been effected.
William H. Pirkle, Athanasios Tsipouras
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ChemInform Abstract: SYNTHESES OF THE NOVEL FURO(3,4‐B)(1,5)BENZODIAZEPINONE AND PYRROLO(3,4‐B)(1,5)BENZODIAZEPINONE SYSTEMS

Chemischer Informationsdienst, 1985
AbstractAusgehend vom Hydroxyisobuttersäureester (Ia) und dem Aminosäureester (Ib) werden, wie im Formelschema angegeben, die anellierten Diazepin‐Derivate (IX) hergestellt.
K. MATSUO, K. TANAKA
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Application of preparative liquid chromatography to the isolation of enantiomers of a benzodiazepinone derivative

Journal of Chromatography A, 1992
The isolation of milligram amounts of the enantiomers of a benzodiazepinone derivative was performed on an analytical cellulose tribenzoate-based column by multiple repetitive injections. An enantiomeric purity greater than 98% was required. First, an analytical method was developed to maximize the resolution by adjusting the mobile phase composition ...
A, Katti, P, Erlandsson, R, Däppen
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Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones

Organic & Biomolecular Chemistry, 2017
Herein is reported a practical method for the construction of 3-benzoylquinoxalinones from benzodiazepinones in the presence of DMSO which serves both as a solvent and an oxidant.
Hasan Mtiraoui, Kevin Renault, Morgane Sanselme, Moncef Msaddek, Pierre-Yves Renard, Cyrille Sabot   +5 more
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Studies related to alkylations of enolate anions of 1,4‐benzodiazepinones

Journal of Heterocyclic Chemistry, 1993
AbstractTreatment of 1,4‐benzodiazepinone derivatives with a Wittig‐Horner reagent, led to the desired carboncarbon bond formation at the amide carbonyl carbon atom in reasonable yield. An examination of this reaction has shown that only secondary amides can be used, indicating that this process requires the amide proton.
R. Ian Fryer, Julia C. Pinto, Ravindra B. Upasani   +2 more
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Concise diastereospecific pyrrolo[1,2-a][1,4]benzodiazepinone synthesis

Tetrahedron, 2007
Abstract A concise synthesis of the novel pyrrolo[1,2-a]benzodiazepine system, by using the metallo carbenoid/spiro-[6,5]-ammonium ylide/Stevens[1,2]-shift with ring-expansion approach, was reported. The overall cascade process resulted stereospecific.
Mauro Mucedda, Daniele Muroni, Antonio Saba, Carlo Manassero   +3 more
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