Results 101 to 110 of about 628 (148)

One Pot Solvent-Free Synthesis of Benzodiazepinones Catalyzed by CuI

Chinese Journal of Organic Chemistry, 2017
Qiong Xiao
exaly   +2 more sources

First Highly Enantioselective Synthesis of Benzodiazepinones by Catalytic Hydrogenation

Advanced Synthesis and Catalysis, 2010
Estíbaliz Merino, René M Koenigs, Magnus Rueping   +2 more
exaly   +2 more sources

Soluble polymer-supported synthesis of benzodiazepinones

Bioorganic & Medicinal Chemistry Letters, 2002
Soluble polymer-supported synthetic method provides a highly efficient route for the construction of biologically important 1,5-benzodiazepin-2-ones. A library of N-substituted benzodiazepinones can be readily assembled utilizing S(N)Ar reaction, reduction of nitro group and one-pot cyclization following N-alkylation as the key step in the synthesis ...
Cheng Yi, Wu, Chung Ming, Sun
openaire   +2 more sources

A new route to 1H-1,5-benzodiazepinones

Journal of the Chemical Society Chemical Communications, 1981
Dimethyl allene-1,3-dicarboxylates react with o-phenylenediamine to give 1H-1, 5-benzodiazepinones and not benzimidazoles; the transient enamine intermediate shows preference for a 7-exo-trig ring closure.
Feodor Scheinmann
exaly   +2 more sources

On substituent effect on the benzodiazepinone system

Computational and Theoretical Chemistry, 2012
Abstract Tautomerism, aromaticity, and electron density at ring critical points of substituted benzodiazepinones, composed of condensed 6- and 7-membered rings (7-substituted 1,3-dihydro-benzo[e][1,4]diazepin-2-ones), were studied at the B3LYP/6-31G ∗∗ level. We found that in the gas phase and in water, the N1H tautomers are more stable than the N4H
Grażyna Karpińska, Aleksander P. Mazurek, Jan Cz. Dobrowolski   +2 more
openaire   +1 more source

Attempted synthesis of 2,4‐ and 1,3‐benzodiazepinones

Journal of Heterocyclic Chemistry, 1975
AbstractThe cyclodehydration reaction performed upon α‐acylamino carboxamides is known to constitute a facile synthetic approach to five‐membered heterocyclic systems. Attempts to prepare 2,4‐ and 1,3‐benzodiazepinone derivatives (VI, XIX) of potential C.N.S. Activity using such methods, proved unsuccessful. A new triazine system (X) which was prepared
Uri Golik, William Taub
openaire   +1 more source

ChemInform Abstract: Synthesis and Reaction of Dihydrofuro(3,4‐b)(1,5)benzodiazepinones and Dihydropyrrolo(3,4‐b)(1,5)benzodiazepinones.

ChemInform, 1987
AbstractThe benzodiazepinones (IV) are obtained by acylation and subsequent cyclization of the diamines (Ia) and (Ib).
K. MATSUO, S. TAKADA, J. INOUE, K. TANAKA   +3 more
openaire   +1 more source

Auranthine, a new benzodiazepinone metabolite of Penicillium aurantiogriseum

Journal of the Chemical Society, Perkin Transactions 1, 1986
A novel metabolite, auranthine, has been isolated from sporing cultures of Penicillium aurantiogriseum and its structure, 6,7,7a,8-tetrahydroquinazolino[3′,2′:1,6]pyrido[2,3-b][1,4]benzodiazepine-9,16-dione comprising anthranilate and glutamine moieties, has been elucidated from spectral evidence and biosynthetic reasoning.
Stephanie E. Yeulet, Peter G. Mantle, John N. Bilton, Henry S. Rzepa, Richard N. Sheppard   +4 more
openaire   +1 more source

ChemInform Abstract: SYNTHESES OF THE NOVEL FURO(3,4‐B)(1,5)BENZODIAZEPINONE AND PYRROLO(3,4‐B)(1,5)BENZODIAZEPINONE SYSTEMS

Chemischer Informationsdienst, 1985
AbstractAusgehend vom Hydroxyisobuttersäureester (Ia) und dem Aminosäureester (Ib) werden, wie im Formelschema angegeben, die anellierten Diazepin‐Derivate (IX) hergestellt.
K. MATSUO, K. TANAKA
openaire   +1 more source

The synthesis of triazolo[1,5-d][1,4]benzodiazepinones and triazolo[4,3-d][1,4]benzodiazepinones, new compounds with cns activity

Tetrahedron Letters, 1976
exaly   +2 more sources