PYRIDO ANALOGS OF PSYCHOPHARMACOLOGICAL AGENTS [PDF]
, 1973 The intramolecular nucleophilic cyclization of 3-pyridyl-alkylamines onto the 2-position of the pyridine ring was invest-igated using a wide variety of experimental conditions.
Davis, Hubert Lorne
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The effectiveness and harms of pharmacological interventions for the treatment of delirium in adults admitted into the intensive care unit after cardiac surgery: a systematic review [PDF]
, 2019 Background: Patients who undergo cardiac surgery are at high risk of delirium (incidence: 50-90%), increasing the risk of death and adversely affecting recovery.
Leigh, Vivienne Margaret
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New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells. [PDF]
Molecules, 2023 Fiore M +8 more
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Synthetic and spectroscopic studies of 1,4-benzodiazepine analogues [PDF]
, 1994 In this project, an extensive range of benzodiazepine analogues have been synthesised via Schmidt reaction of specially prepared flavanone, 4-quinolone and l-thioflavanone precursors; nitrogen insertion being effected by use of trimethylsilyl azide in ...
Mphahlele, Malose Jack
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Design, synthèse et criblage de chimiothèques peptidomimétiques pour la découverte d'agents antinéoplasiques [PDF]
, 2018 Le criblage des interactions protéine-protéine représente une approche thérapeutique prometteuse et novatrice qui est encore sous-exploitées par l’industrie pharmaceutique et la recherche biomédicale.
Vézina-Dawod, Simon
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Identification and Characterization of Potential BRDT(1) Inhibitors by Fragment-Based Screening Using Differential Screening Fluorimetry and Orthogonal Techniques [PDF]
, 2019 University of Minnesota Ph.D. dissertation.May 2019. Major: Medicinal Chemistry. Advisor: Gunda Georg. 1 computer file (PDF); xii, 252 pages.Almost 60 years after the advent of the female oral contraceptive pill, there are now a plethora of hormonal ...
Wisniewski, Andrea
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Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition. [PDF]
Bioorg Med Chem Lett, 2023 Lee S +9 more
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Investigating the role of benzodiazepines in drug-related mortality: A systematic review undertaken on behalf of The Scottish National Forum on Drug-Related Deaths [PDF]
, 2016 Owing to a lack of research on benzodiazepines, the National Forum on Drug-Related Deaths commissioned work addressing why benzodiazepines are common in DRDs and what role they play in such deaths, particularly at the high doses often reported.
Barnsdale, Lee R +2 more
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Facile synthesis of 4-substituted 1,2,4,5-tetrahydro-1,4-benzodiazepin- 3-ones by reductive cyclization of 2-chloro-N-(2-nitrobenzyl)acetamides [PDF]
A facile and efficient method was developed for the synthesis of 1,2,4,5-tetrahydro-1,4-benzodiazepine-3-ones from 2-chloro-N-(2-nitrobenzyl)acetamides through a reductive cyclization using iron-ammonium chloride in ethanol–water in good yields.
Barri, Iván Alejandro +4 more
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Microwave-Assisted Post-Ugi Reactions for the Synthesis of Polycycles. [PDF]
Molecules, 2022 Song L, Cai L, Van der Eycken EV.
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