Results 31 to 40 of about 600 (168)
Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021 Since its inception, the coronavirus disease 2019 (COVID‐19) pandemic has infected millions of people around the world. Therefore, it is necessary to find effective treatments against Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2), as it is the viral source of COVID‐19.
Mohammad Bagher Majnooni +6 more
wiley +1 more source
Cytotoxic Benzophenanthridine and Furoquinoline Alkaloids from Zanthoxylum buesgenii(Rutaceae) [PDF]
Chemistry Central Journal, 2014 Zanthoxylum buesgenii is a shrub used in Sierra Leone as remedy to cure venereal diseases, arthritis, and rheumatism whereas leaves and barks are employed to treat leprosy and to relieve pain. In South West Region of Cameroon, the plant locally called "Mbem" by Lewoh-Lebang community, is orally given to patients as aphrodisiac decoction and to increase
Sandjo, Louis P +4 more
openaire +2 more sources
In vitro cytotoxic activity of african plants: a review [PDF]
, 2022 In African countries, cancer not only is a growing problem, but also a challenge because available funding and resources are limited. Therefore, African medicinal plants play a significant role in folk medicine and some of them are traditionally used for
Canga, Isabel +4 more
core +2 more sources
Synthesis and Antileukemia Activity Evaluation of Benzophenanthridine Alkaloid Derivatives
Molecules, 2022 Thirty-three benzophenanthridine alkaloid derivatives (1a–1u and 2a–2l) were synthesized, and their cytotoxic activities against two leukemia cell lines (Jurkat Clone E6-1 and THP-1) were evaluated in vitro using a Cell Counting Kit-8 (CCK-8) assay.
Yaling Tang +4 more
openaire +3 more sources
Creative research in the chemical industry– four decades in retrospect [PDF]
, 2006 My professional research career spanning more than four decades has been largely devoted to synthetic medicinal chemistry (Ciba, Bombay-now Mumbai-21 years) followed by an equal number of years in process development of drugs, crop protection chemicals ...
A Guggisberg +78 more
core +1 more source
Transition-metal-catalyzed functionalization of alkynes with organoboron reagents: new trends, nechanistic insights, and applications [PDF]
, 2021 Catalytic functionalization of alkynes with organoboron reagents provides a straightforward access to stereochemically defined multisubstituted alkenes, which are structural motifs commonly found in bioactive compounds and organic materials.
Arrayás, Ramón Gómez +3 more
core +1 more source
MolbankZanthoxylum simulans Hance, commonly known as Sichuan pepper, is a well-known medicinal plant recognized for its potential as a source of bioactive specialized metabolites.
Diego Cárdenas-Laverde +2 more
doaj +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.ABSTRACT Cytochrome P450 3A4 (CYP3A4) is one of the most important members of the cytochrome P450 subfamily, which is involved in the catalytic process of many drug activation or deactivation. Meanwhile, it is also a risk factor for drug‐induced toxic reactions.
Fang Wang +7 more
wiley +1 more source
Cytotoxic Benzophenanthridine and Benzylisoquinoline Alkaloids from Argemone mexicana
Zeitschrift für Naturforschung C, 2003 Abstract Fractionation of the chloroform extract from the aerial part of Argemone mexicana led to the isolation of two benzophenanthridine-type alkaloids, N-demethyloxysanguinarine and pancorine; three benzylisoquinoline-type alkaloids, (+)-1,2,3,4-tetrahydro-1-(2-hydroxymethyl- 3,4-dimethoxyphenylmethyl)-6,7-methylenedioxyisoquinoline, (
Yuh-Chwen, Chang +4 more
openaire +2 more sources
Alkaloids of Papaver libanoticum and their cytotoxic activity [PDF]
, 2018 Papaver libanoticum (family Papaveraceae) is an endemic Lebanese plant that has not been investigated before. The plant extract was found to possess a potent opioid analgesic activity with characteristic profile that suggest its potential use for the ...
Aboul-Ela, Maha +5 more
core +1 more source