Results 11 to 20 of about 625 (182)
Dynamic conversions of single molecules can be monitored at doubly cucurbit[7]uril‐functionalized supramolecular junctions. Through this intermolecular recognition tunneling technique, the molecular conductance of different analytes and analyte mixtures can be finger‐printed in dependence on pH and competitive salts, showcasing the first examples of ...
Bohuai Xiao +8 more
wiley +2 more sources
Abstract Genus Corydalis is a rich source of isoquinoline alkaloids reported to having potential bioactivities. Corydalis chaerophylla collected from Nepal at an altitude of 2400–4800 m was extracted using hexane, methanol and chloroform as solvents. The resulting hexane, methanol and chloroform extracts were subjected to LC–DAD‐MSn analysis to yield ...
Binita Maharjan +7 more
wiley +1 more source
This manuscript aims to investigate different herbal feed additives as alternative to antibiotic growth promoters (AGPs). For this purpose, medium‐chain fatty acids (MCFAs) or phytobiotics (essential oils [EOs] and alkaloids [ALKs]) and blended feed additives have been used.
Necmettin Ceylan +5 more
wiley +1 more source
Advances in the natural α‐glucosidase inhibitors
Natural products are a great source for the development of new α‐glucosidase (AG) inhibitory drug candidates. We aim to summarize advances in natural AG inhibitors according to their secondary metabolite groups in the last decade. Their mechanisms of action and structure–activity relationships will especially be discussed.
Didem Şöhretoğlu +4 more
wiley +1 more source
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Macleaya cordata (Willd.) R. Br. extract and leaves (Sangrovit® Extra) when used as a zootechnical feed additive (functional group: other zootechnical additives) for all poultry species (excluding laying and breeding ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
wiley +1 more source
While common methods giving access to N‐substituted‐pyrrolo‐[3,4‐b]‐quinoline‐1,3‐diones consist of multistep synthesis involving quinoline‐based substrates, a broadly applicable one‐step palladium‐catalyzed carbonylative imidization‐cyclization process has been developed starting from 3‐bromo‐2‐iodoquinoline, that opens new perspectives for the ...
Sami Chniti +4 more
wiley +1 more source
Sanguinarine reductase, a key enzyme of benzophenanthridine detoxification [PDF]
ABSTRACTCultured cells of Eschscholzia californica respond to a yeast glycoprotein elicitor by producing benzophenanthridine alkaloids, which are excreted into the cell wall and the outer medium. These compounds, preferentially sanguinarine, are efficient phytoalexins because of their ability to intercalate double‐stranded DNA (dsDNA), penetrate ...
Dagmar, Weiss +3 more
openaire +4 more sources
Sanguinarine synergistically potentiates aminoglycoside‐mediated bacterial killing
Aminoglycosides primarily interact with the bacterial ribosomes and result in protein misfolding and ROS production. Insertion of abnormal proteins into the cell membrane increases the membrane permeability and leads to enhanced uptake of sanguinarine.
Chang Lu +6 more
wiley +1 more source
Inflammatory diseases are a common therapeutic problem and nonsteroidal anti‐inflammatory drugs are not deprived of side effects, of which ulcerogenic activity is one of the most frequent. The aim of the study was to evaluate the anti‐inflammatory activity of the sanguinarine‐chelerythrine (SC) fraction of Coptis chinensis and its influence on the ...
Maciej Danielewski +12 more
wiley +1 more source
The genus Papaver is highly esteemed in the pharmacy industry, in the culinary field, and as ornamental plants. These plants are also valued in traditional medicine. Among all Papaver species, Papaver somniferum L. (opium poppy) is the most important species in supplying phytochemicals for the formulation of drugs, mainly alkaloids like morphine ...
Monica Butnariu +21 more
wiley +1 more source

