Results 41 to 50 of about 625 (182)
Some recent work on Schiff bases, imines and iminium salts in synthetic heterocyclic chemistry - a review [PDF]
, 1984 This review summarizes the versatile use of Schiff bases, imines and iminium salts for synthesizing a great variety of heterocyclic compounds. Addition reactions of Schiff bases with acid anhydrides, acid chlorides and esters have led to the synthesis of
Chandrasekaran, Sundaram +7 more
core +1 more source
Bioactive Compounds in Phytomedicine [PDF]
, 2021 There are significant concerns regarding the potential side effects from the chronic use of conventional drugs such as corticosteroids, especially in children.
core +1 more source
Natural products targeting tumour angiogenesis
British Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu +2 more
wiley +1 more source
Metabolic Reprogramming of Cancer by Chemicals that Target Glutaminase Isoenzymes. [PDF]
, 2020 Background: Metabolic reprogramming of tumours is a hallmark of cancer. Among the changes in the metabolic network of cancer cells, glutaminolysis is a key reaction altered in neoplasms. Glutaminase proteins control the first step in glutamine metabolism
Alonso-Carrión, Francisco José +5 more
core +1 more source
Archiv der Pharmazie, Volume 357, Issue 7, July 2024.Since the Chelidonium majus (greater celandine) alkaloid sanguinarine has recently been characterized as a dual peroxisome proliferator‐activated receptor‐α/γ ligand, sanguinarine and structurally related alkaloids were screened on nuclear receptors. Berberine and chelidonine were identified as Chelidonium majus alkaloids with selectivity for the two ...
Sohrab Salehi +5 more
wiley +1 more source
Alkaloids of Papaver libanoticum and their cytotoxic activity [PDF]
, 2018 Papaver libanoticum (family Papaveraceae) is an endemic Lebanese plant that has not been investigated before. The plant extract was found to possess a potent opioid analgesic activity with characteristic profile that suggest its potential use for the ...
Aboul-Ela, Maha +5 more
core +1 more source
Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives
World Journal of Gastrointestinal Oncology, 2016 Historically, natural products have represented a significant source of anticancer agents, with plant-derived drugs becoming increasingly explored. In particular, sanguinarine is a benzophenanthridine alkaloid obtained from the root of Sanguinaria canadensis, and from other poppy Fumaria species, with recognized anti-microbial, anti-oxidant and anti ...
GAZIANO, ROBERTA +5 more
openaire +4 more sources
Cytotoxic Benzophenanthridine and Furoquinoline Alkaloids from Zanthoxylum buesgenii(Rutaceae) [PDF]
Chemistry Central Journal, 2014 Zanthoxylum buesgenii is a shrub used in Sierra Leone as remedy to cure venereal diseases, arthritis, and rheumatism whereas leaves and barks are employed to treat leprosy and to relieve pain. In South West Region of Cameroon, the plant locally called "Mbem" by Lewoh-Lebang community, is orally given to patients as aphrodisiac decoction and to increase
Sandjo, Louis P +4 more
openaire +2 more sources
Biosynthesis of the Amaryllidaceae alkaloids [PDF]
, 2014 Amaryllidaceae alkaloids (AAs) are a structurally diverse group of plant specialized metabolites with powerful biological activities. The medicinal properties of many AAs have been identified including the antitumor agent narciclasine and galanthamine ...
Desgagné-Penix, Isabel, Singh, Aparna
core +2 more sources