Results 41 to 50 of about 540 (159)

Screening of Chelidonium majus isoquinoline alkaloids reveals berberine and chelidonine as selective ligands for the nuclear receptors RORβ and HNF4α, respectively

open access: yesArchiv der Pharmazie, Volume 357, Issue 7, July 2024.
Since the Chelidonium majus (greater celandine) alkaloid sanguinarine has recently been characterized as a dual peroxisome proliferator‐activated receptor‐α/γ ligand, sanguinarine and structurally related alkaloids were screened on nuclear receptors. Berberine and chelidonine were identified as Chelidonium majus alkaloids with selectivity for the two ...
Sohrab Salehi   +5 more
wiley   +1 more source

The Role of the Iminium Bond in the Inhibition of Reverse Transcriptase by Quaternary Benzophenanthridines

open access: yes, 1998
The quaternary benzo[c]phenanthridines fagaronine, nitidine and O-methylfagaronine have been reviewed as potential antitumour and antiviral agents. Their mode of action has not been established, but their ability to bind with DNA by intercalation is ...
Simon P Mackay   +3 more
core   +1 more source

Búsqueda racional de alcaloides isoquinolínicos del género Zanthoxylum (Rutaceae) como posibles agentes multifuncionales para el tratamiento del Alzheimer [PDF]

open access: yes, 2020
Los trastornos neurodegenerativos multifactoriales, como la enfermedad de Alzheimer (EA), son un problema creciente de salud pública mundial debido al aumento de su incidencia y la baja efectividad de los tratamientos actuales. Dado que la farmacoterapia
Plazas González, Erika Andrea
core   +1 more source

Cytotoxic Benzophenanthridine and Benzylisoquinoline Alkaloids from Argemone mexicana

open access: yesZeitschrift für Naturforschung C, 2003
Abstract Fractionation of the chloroform extract from the aerial part of Argemone mexicana led to the isolation of two benzophenanthridine-type alkaloids, N-demethyloxysanguinarine and pancorine; three benzylisoquinoline-type alkaloids, (+)-1,2,3,4-tetrahydro-1-(2-hydroxymethyl- 3,4-dimethoxyphenylmethyl)-6,7-methylenedioxyisoquinoline, (
Yuh-Chwen, Chang   +4 more
openaire   +2 more sources

Schematic representation of BIA pathway.

open access: yes, 2013
Biosynthetic pathway and corresponding enzymes leading to synthesis of benzylisoquinolines (papaverine, reticuline, laudanine), morphinans (thebaine, oripavine, codeine, morphine), protoberberines (berberine), phthalideisoquinolines (narcotoline ...
Vineeta Triptahi (277738)   +6 more
core   +1 more source

Die Rolle der Sanguinarinreduktase in der Kontrolle des Benzophenanthridin-Metabolismus in Pflanzen [PDF]

open access: yes, 2013
Die Sanguinarinreduktase (SR) reduziert die von Eschscholzia californica produzierten hochgiftigen Benzophenanthridinalkaloide zu den weniger toxischen Dihydroalkaloiden.
Müller, Henriette Ulrike
core   +1 more source

On alkaloids from the aerial parts of three Eschscholtzia species

open access: yes, 1986
In the aerial parts of Eschscholtzia californica CHAM., E. douglasii (HOOK. etARN.) WALP. and E. glauca GREENE the main alkaloidal component is the quaternary base californidine.
Leonora Slavíková, Jiří Slavík
core   +1 more source

Development of Antitumor Compounds Led by Benzophenanthridine Compounds [PDF]

open access: yes, 2001
1.簡単なフェネチルアミン体とベンズアルデヒド体から、同一の合成中間体を経由するプロトベルベリン及び13-メチルプロトベルベリンの新しい簡便な一般合成法を開発した。本法を用いて、ベルベリンを始め各種プロトベルベリンアルカロイドを合成した。 2.プロトベルベリンからエナミン体を経由する、ベンゾフェナンスリジンの短工程による新しい生合成的合成法を開拓した。本法を用いて、ケレリスリンやニチジンなどのベンゾフェナンスリジンアルカロイドの全合成に成功した。 3.パラジウム触媒を用いた ...
花岡, 美代次, 80028844, 27759
core   +1 more source

Fluorescence properties of some isoquinoline alkaloids

open access: yes, 1985
The fluorescence properties of 28 isoquinoline alkaloids have been investigated. In most of them the chromophore responsible for fluorescence was the benzene ring with electron-donor substituents containing oxygen.
Hana Klukanová   +4 more
core   +1 more source

Mechanism of Formation of Heterocyclic Compounds by Reaction of Hydrazoic Acid with Cyclic Compounds: Synthesis of Benzoxazines. [PDF]

open access: yes, 2018
2-a-Naphthoyl- , 2-p-methoxybenzoyl-, 2-p-chlorobenzoyl-, 2-m-nitrobenzoyl-, 2-mesitoyl-, 2-phenylacetyl-, and 2-butyryl-benzoic acids, and benzylidene- and propylidene-phthalides have been subjected to the conditions of the Schmidt reaction to yield ...
Marks, Robert Edward.
core   +1 more source

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