Results 101 to 110 of about 2,430 (167)

Antihypertensive Medications and Risk of Melanoma and Keratinocyte Carcinomas: A Systematic Review and Meta-Analysis. [PDF]

JID Innov
Cohen OG, Taylor M, Mohr C, Nead KT, Hinkston CL, Giordano SH, Langan SM, Margolis DJ, Wehner MR.   +8 more
europepmc   +1 more source

Simultaneous Determination of Valsartan and Hydrochlorothiazide in Tablets by RP-HPLC.

Indian J Pharm Sci, 2008
Tian DF, Tian XL, Tian T, Wang ZY, Mo FK.   +4 more
europepmc   +1 more source

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Copper-promoted aerial oxidation of benzothiadiazines: access to benzothiadiazine S-oxide heterocycles

Dalton Transactions, 2015
Aerial oxidation of benzothiadiazines selectively affords the corresponding benzothiadiazine S-oxides in the presence of Cu2+ ions. Structural studies reveal that the S-oxide appears to be a strong hydrogen-bond acceptor.
Bryce J. Leontowicz, Melanie Pilkington, Muhammad U. Anwar, Ewan R. Clark, Jeremy M. Rawson, Jeremy M. Rawson, John J. Hayward   +6 more
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Hydrolysis of Benzothiadiazines

Journal of Pharmaceutical Sciences, 1971
The hydrolysis of hydrochlorothiazide and two other hydrothiazides was studied as a function of pH. Reversible kinetics were observed for the hydrolytic reaction, and a bell-shaped pH-rate profile was obtained. The equilibrium constant, however, was relatively independent of hydrogen-ion concentration.
J.B. Smith, H.K. Govan, C.R. Rehm, J.A. Mollica   +3 more
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Determination of kinetic parameters of enantiomerization of benzothiadiazines by DCXplorer

Chirality, 2010
AbstractBenzothiadiazines differently substituted at the sulfonamidic nitrogen atom, at the stereogenic carbon atom and at the anilinic nitrogen atom have been synthesized and fully characterized. Enantioseparation of these compounds has revealed rapid on‐column enantiomerization.
CANNAZZA, Giuseppe, CARROZZO, Marina Maria, BATTISTI, UMBERTO MARIA, BRAGHIROLI, Daniela, PARENTI, Carlo, Troisi, Alessandro, Troisi, Luigino   +6 more
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Further Observations Concerning the Hyperglycemic Activity of Benzothiadiazines

Diabetes, 1964
Hyperglycemia has been produced by a series of BZD in the normal rat. Diazoxide is the most potent hyperglycemic agent examined in this series and its action is complemented by combination with several other BZD. Examination in pregnant rats showed a complementary activity between diazoxide and trichlormethiazide, which had not been obtained in the ...
William W. Parmley, Frederick W. Wolff
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Binding of diazoxide and other benzothiadiazines to human albumin

Biochemical Pharmacology, 1974
Abstract The binding of seven benzothiadiazines to human albumin was studied by equilibrium dialysis. All these 1,2,4-benzothiadiazine-1,1-dioxide analogs are highly bound to human albumin. The unsubstituted benzothiadiazine nucleus is bound less than the substituted analogs.
Edward M. Sellers, Jan Koch-Weser
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Metabolic Effects of Diuretic and Nondiuretic Benzothiadiazines.

Annals of Internal Medicine, 1964
Excerpt A double-blind study of the metabolic effects of trichlormethiazide (TCZ) and diazoxide was performed in 45 hypertensive patients.
Ronald Okun, William R. Wilson, R. Patterson Russell, Daniel B. Stone   +3 more
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Quinazolinones/Benzothiadiazines as Amidyl/Aminyl Radical Precursors for Controlled Cascade Cyclization via Photocatalyzed PCET.

Organic Letters, 2022
Quinazolinones/benzothiadiazines were used as amidyl/aminyl radical precursors for cascade cyclizations via a photoredox-catalyzed proton-coupled electron transfer (PCET) process for the first time.
Mandapati Bhargava Reddy, K. Prasanth, Nalladhambi Neerathilingam, R. Anandhan   +3 more
semanticscholar   +1 more source

Tandem Reduction, Ammonolysis, Condensation, and Deamination Reaction for Synthesis of Benzothiadiazines and 1-(Phenylsulfonyl)-1H-benzimidazoles.

Journal of Organic Chemistry, 2022
A novel route for a SnCl2-promoted tandem reduction, ammonolysis, condensation, and deamination reaction which uses nitrile and 2-nitro-N-phenylbenzenesulfonamide/N-(2-nitrophenyl)benzenesulfonamide to synthesize derivatives of benzothiadiazine/1 ...
Xiao Yu, Zhihong Ma, Wenjing Zhu, Hongyan Liu, Zenghui Zhang, Yi Liu, Mei Zhang, Jinbo Zhao, Pengfei Zhang, Chengcai Xia   +9 more
semanticscholar   +1 more source