A Comprehensive Photochemical and Photophysical Assay Exploring the Photoreactivity of Drugs [PDF]
What are the interests of a pharmaceutical company in «Photochemistry of Drugs» ? First of all drug-safety: safety by avoiding adverse effects in humans caused by exposure to light after the administration of certain drugs.
Oppenländer, Thomas
core +2 more sources
Identificación y caracterización de los productos de degradación de las benzotiadiazinas en orina humana. Importancia para el control antidoping [PDF]
Los diuréticos de tipo tiazidas (benzotiadiazinas) son ampliamente usados con fines terapéuticos. Al igual que otros diuréticos pueden ser utilizados ilegalmente en el deporte con el objetivo de evitar resultados positivos en el control antidoping por ...
Arístides Rosado Pérez +4 more
core +4 more sources
Classification of HCV NS5B Polymerase Inhibitors Using Support Vector Machine [PDF]
Using a support vector machine (SVM), three classification models were built to predict whether a compound is an active or weakly active inhibitor based on a dataset of 386 hepatitis C virus (HCV) NS5B polymerase NNIs (non-nucleoside analogue inhibitors)
Aixia Yan +36 more
core +4 more sources
Transformation of 2H-1,2,3-benzothiadiazine 1,1-dioxides variously substituted at the aromatic ring, via nucleophilic substitution and demethylation reactions [PDF]
Imre Gyűjtő +6 more
openalex +1 more source
An Assessment of the Use of Chimpanzees in Hepatitis C Research Past, Present and Future: 2. Alternative Replacement Methods [PDF]
The use of chimpanzees in hepatitis C virus (HCV) research was examined in the report associated with this paper (1: Validity of the Chimpanzee Model), in which it was concluded that claims of past necessity of chimpanzee use were exaggerated, and that ...
Ahn J. +23 more
core +2 more sources
Clinical Pharmacology of Antihypertensive Therapy for the Treatment of Hypertension in CKD [PDF]
CKD is common and frequently complicated with hypertension both predialysis and in ESKD. As a major modifiable risk factor for cardiovascular disease in this high-risk population, treatment of hypertension in CKD is important.
Agarwal, Rajiv, Sinha, Arjun D.
core +1 more source
Antiviral Therapy for Hepatitis C Virus: Beyond the Standard of Care [PDF]
Hepatitis C virus (HCV) represents a major health burden, with an estimated 180 million chronically infected individuals worldwide. These patients are at increased risk of developing liver cirrhosis and hepatocellular carcinoma. Infection with HCV is the
Afdhal +69 more
core +4 more sources
ELECTROLYTE CONSERVATION DURING THE TREATMENT OF DIABETES INSIPIDUS WITH BENZOTHIADIAZINES [PDF]
G. C. Kennedy, Lisa Hill
openalex +1 more source
In silico identification of promising inhibitor against RNA-dependent RNA polymerase target of SARS-CoV-2. [PDF]
Singh P +4 more
europepmc +1 more source

