Results 151 to 160 of about 1,407 (189)

Azole derivatives of 1,4-benzothiazine as antifungal agents

Bioorganic & Medicinal Chemistry, 1998
A series of azole derivatives of 1,4-benzothiazine 7-14 was synthesized and evaluated for the in vitro and in vivo activity against Candida albicans. Secondary alcohol 10 and its ether derivative 13 showed very good efficacy against systemic candidiasis in a murine experimental model.
FRINGUELLI, Renata, SCHIAFFELLA, Fausto, BISTONI, Francesco, PITZURRA, Lucia, VECCHIARELLI, Anna   +4 more
openaire   +4 more sources

Trimeric aldolization product of 1,4-benzothiazine

Journal of the Chemical Society, Chemical Communications, 1977
2H-1,4-Benzothiazine, the parent system of the mammalian phaeomelanic pigments, is a highly unstable molecule which readily undergoes a reversible aldolization to form, mainly, the cyclic trimer (5).
Chioccara F., NOVELLINO, ETTORE, Prota G., Sodano G.   +3 more
openaire   +2 more sources

Cycloaddition reactions of 1,3-benzothiazines - 6. Reactions of 1,3-benzothiazine derivatives with substituted acetyl chlorides

Tetrahedron, 1984
Abstract 6, 7-Dimethoxy-2 H -l,3-benzothiazine derivatives ( 1 , 8 ) react with substituted acetyl chlorides to give angularly condensed β -lactams ( 3a - d , 10 , 11 ). The cis compound 11 was epimerised to the trans derivative 12 .
Pál Sohár, Lajos Fodor, János SzabÓ, Gábor BernÁth   +3 more
openaire   +1 more source

ChemInform Abstract: UMLAGERUNG VON BENZOTHIAZIN‐SULFOXIDEN

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractOxidation des Dihydrobenzothiazins (I) mit m‐Chlorperbenzoesäure (II) in Chloroform bei ‐8°C führt zum Sulfoxid (III), das mit Essigsäureanhydrid/Natriumacetat ein 3:2‐Gemisch der Verbindungen (IV) und (V) in guter Ausbeute liefert.
R. B. MORIN, D. O. SPRY
openaire   +1 more source

ChemInform Abstract: 1,4‐BENZOTHIAZIN 2. MITT.

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractDas durch Reaktion des Aminothiols (I) mit dem Ester (II) entstandene Produkt wird in äthanolischer Lösung durch Luftoxidation in die Isomeren (III) und (IV) übergeführt.
FRANCESCO DURO, PASQUALE CONDORELLI, GIANCARLO SCAPINI, GIOVANNI PAPPALARDO   +3 more
openaire   +1 more source

[New benzothiazines. II. 2H-1,2-benzothiazin-3(4H)-one 1,1-dioxide and 1H-2,3-benzothiazin-4(3H)-one 2,2-dioxide].

Chemische Berichte, 1970
E, Sianesi, R, Redaelli, M, Bertani, P, Da Re   +3 more
openaire   +4 more sources

ChemInform Abstract: 1,4‐Benzothiazines, Dihydro‐1,4‐benzothiazines and Related Compounds

Chemischer Informationsdienst, 1985
C. BROWN, R. M. DAVIDSON
openaire   +1 more source

1,4-Benzothiazine analogues and apoptosis

Bioorganic & Medicinal Chemistry, 2003
Renata Fringuelli, Fausto Schiaffella, M.Pilar Utrilla Navarro, Lara Milanese, Cristina Santini, Michela Rapucci, Cristina Marchetti, Carlo Riccardi   +7 more
openaire   +1 more source

1,2-Benzothiazines. 6. 3-Carbamoyl-4-hydroxy-2H-1,2-benzothiazine 1,1-dioxides as antiinflammatory agents

Journal of Medicinal Chemistry, 1973
H, Zinnes, N A, Lindo, J C, Sircar, M L, Schwartz, J, Shavel, G, DiPasquale   +5 more
openaire   +2 more sources

Dilithiation of a 2,1-Benzothiazine

HETEROCYCLES, 2016
Michael Harmata, Nathan L. Calkins
openaire   +1 more source