Results 61 to 70 of about 1,143 (191)

Enantioselective Synthesis of Chiral-at-Sulfur 1,2-Benzothiazines by (CpRhIII)-Rh-x-Catalyzed C-H Functionalization of Sulfoximines [PDF]

, 2018
Sulfoximines with stereogenic sulfur atoms are attractive structural motifs in drug discovery. A direct catalytic enantioselective method for the synthesis of sulfur-chiral 1,2-benzothiazines from readily accessible diaryl sulfoximines is presented ...
Sun, Yang, Cramer, Nicolai, Yang Sun, Nicolai Cramer, Cramer N, Sun Y   +5 more
core   +2 more sources

Organic Electrochemical Transistors Monolithically Integrated with Precise Micro‐Dispensing Enable High‐Performance Biosignals Amplification

Advanced Science, Volume 12, Issue 40, October 27, 2025.
This research showcases a micro‐dispensing strategy for integrating high‐performance organic electrochemical transistors (OECTs) and amplifiers onto flexible substrates. The method achieves precise material deposition, enabling fully micro‐dispensed OECT amplifiers with a record 1 MHz gain‐bandwidth product.
Roberto Granelli, Virginia M. Demartis, Giulia Frusconi, Zsolt M. Kovács‐Vajna, Fabrizio Torricelli   +4 more
wiley   +1 more source

Benzothiazines in Organic Synthesis. The Preparation of Enantiomerically Pure 4-Substituted Quinolones

, 2016
3,4-Dihydroquinolin-2(1H)-ones have potential biological and pharmacological significance. Enantiomerically pure benzothiazines, readily available via an intramolecular addition of a sulfoximine-stabilized carbanion to an α,β-unsaturated ester, could be ...
Michael Harmata (746967), Xuechuan Hong (790032)   +1 more
core   +1 more source

A New Synthesis of 4H-1,4-Thiazines and Benzothiazines

, 1978
Benzothiazines I [R1 = H, R2 = Me, Ph; R1 = Me, R2 = Ph; R1R2 = (CH2)4] and thiazines II [R1 = H, R2 = Me; R1R2 = (CH2)4] were prepd. in 23-59% yield by treatment of III or IV with p-MeC6H4SO3H in MePh at reflux for 30 min. III were prepd.
E. Novellino, F. Chioccara, G. Prota, OLIVA, Leone, Giuseppe PROTA, Francesco CHIOCCARA, Ettore NOVELLINO, Leone OLIVA   +7 more
core   +1 more source

Solid‐Phase Synthesis of 1,3,5,6‐Tetra‐Substituted 3,5‐Dihydroimidazo[4,5‐c][1,2]Thiazin‐4(1 H)‐One 2,2‐Dioxide Derivatives

Journal of Heterocyclic Chemistry, Volume 62, Issue 9, Page 938-943, September 2025.
Through an efficient solid‐phase synthesis method, 32 different 1,3,5,6‐tetra‐substituted 3,5‐dihydroimidazo[4,5‐c][1,2]thiazin‐4(1H)‐one 2,2‐dioxide derivatives were synthesized. The derivative library, with a total of four diversities, showed an overall yield of 7%–32% over 8 steps.
Jimin Moon, Hyojin Lee, Sohee Kim, Taeho Lee   +3 more
wiley   +1 more source

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

ChemMedChem, Volume 20, Issue 14, July 18, 2025.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukič, Daniele Zampieri   +6 more
wiley   +1 more source

N-(2,3-Dimethylphenyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

Acta Crystallographica Section E, 2009
In the crystal structure of the title compound, C18H18N2O4S, the thiazine ring adopts a distorted half-chair conformation. 1,2-Benzothiazines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of ...
doaj   +1 more source

Design of Intrinsically Stable Hole‐Selective Self‐Assembled Monolayers by Introducing Fused‐Ring Intramolecular Donor–Acceptor Interactions

Angewandte Chemie, Volume 137, Issue 28, July 7, 2025.
Herein, we develop a novel SAM molecular design strategy by introducing fused‐ring intramolecular donor–acceptor (D–A) interactions. The designed molecule, JJ32, features a benzo[5,6][1,4]thiazino[2,3‐b]quinoxaline skeleton, where strong D–A interactions enhance charge delocalization and downshift the LUMO energy level.
Wenlin Jiang, Baobing Fan, Lingchen Kong, Ze‐Fan Yao, Wansong Shang, Chun‐To Wong, Francis R. Lin, Alex K.‐Y. Jen   +7 more
wiley   +1 more source

Cp*Ir(iii)-catalyzed C–H/N–H functionalization of sulfoximines for the synthesis of 1,2-benzothiazines at room temperature

, 2018
The first Cp*Ir(iii)-catalyzed C–H/N–H bond functionalization of sulfoximines with α-diazocarbonyl compounds has been developed for the synthesis of 1,2-benzothiazines under redox-neutral conditions at room temperature.
Yogesh N. Aher, Amit B. Pawar, Dhanaji M. Lade   +2 more
core   +1 more source

Synthesis of 1,3-benzothiazines by intramolecular dehydrogenative C–S cross-coupling in a flow electrolysis cell [PDF]

, 2019
(#br)Dehydrogenative cyclization of thioamides is an attractive approach for the synthesis of S -heterocycles. Reported herein is an electrochemical dehydrogenative cyclization reaction of N -benzyl thioamides in a flow electrolysis cell.
Hai-Chao Xu, Chong Huang
core   +1 more source