Results 71 to 80 of about 1,407 (189)
Pigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.ABSTRACT Intra‐tumoral heterogeneity poses a major challenge to treating and managing cancer patients. A characteristic feature of melanoma is its composition of cancer cells with typically heterogeneous content of melanin pigment, the production of which is a hallmark of normal melanocytic differentiation but of poorly understood consequence in ...
Clare Fedele +9 more
wiley +1 more source
Archiv der Pharmazie, Volume 358, Issue 5, May 2025.The pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐dioxide class was investigated with the aim of enlarging the array of Staphylococcus aureus NorA efflux pump inhibitors. The ethidium bromide efflux assay was used as a first indication of NorA inhibition; then, the ability of compounds to synergize with ciprofloxacin (CPX) against both wild‐type and resistant ...
Giada Cernicchi +14 more
wiley +1 more source
Синтез та біологічна активність трифторометилзаміщених анілідів 4-гідрокси-2,2-діоксо-1Н-2λ6,1-бензотіазин-3-карбонових кислот [PDF]
, 2015 In order to reveal the regularities of the “structure – biological activity” relationship by interaction of esters of 1-R-4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazin-3-carboxylic acids and trifluoromethyl substituted anilines in boiling xylene with good ...
Dzyubenko, S. P. +3 more
core +2 more sources
Journal of Cosmetic Dermatology, Volume 24, Issue 4, April 2025.ABSTRACT Background The aesthetic issues caused by pigmentation are increasing people's demand for skin whitening. Considering its long‐term use, it is very important for searching safe and effective agents. Pomegranate flower, a kind of traditional Chinese medicine, has shown promising anti‐inflammatory, antioxidant, and antidiabetic properties, but ...
Peng Shu +6 more
wiley +1 more source
Synthesis and Photophysical Studies of Nitrogen Heterocycles Containing Benzothiazines, Benzothiazoles, Indoles and Quinolines [PDF]
, 2021 Nitrogen heterocycles such as quinolines, benzothiazines, benzothiazoles, and indoles are widely found in nature and these compounds have significance in organic and medicinal chemistry, biochemistry as well as materials science.
Patel, Ealin N
core +1 more source
2,1-Benzothiazines : preparation and reactivity [PDF]
, 2018 Title from PDF of title page (University of Missouri--Columbia, viewed on May 24, 2010). ; The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. ; Dissertation advisor: Dr. Michael Harmata. ; Vita. ; Ph. D. University of Missouri--
openaire +2 more sources
The Plant Journal, Volume 122, Issue 2, April 2025.SUMMARY Over the past few decades, significant advancements have been made in understanding how plasma‐membrane localised receptor kinases (RKs) detect signals and activate responses to various stimuli. Numerous examples of ligand‐induced receptor activation mechanisms and their downstream consequences have been characterised in detail.
Sergio Martin‐Ramirez +2 more
wiley +1 more source
On the deprotonation of chlorothiazide
Acta Crystallographica Section C, Volume 81, Issue 2, Page 102-108, February 2025.The structures of the Na and K salt forms of chlorothiazide have been re‐investigated and are found to have different hydration states and deprotonation sites from those described previously. The structure of the Cs salt form is found to contain the same anion as in the new models for the Na and K salt forms.Three alkali metal salt forms of the ...
Rowan K. H. Brydson +5 more
wiley +1 more source
Studies on 1,4-benzothiazines. II. Acetylation of 2,3-dihydro-3-imino-4H-1,4-benzothiazine.
Chemical and Pharmaceutical Bulletin, 1979 In a previous paper, we described the formation of the 8, 5-diazaphenothiazino [8, 7-h]-phenothiazine derivative (2) by acetylation of 2, 3-dihydro-3-imino-4-methyl-4H-1, 4-benzothiazine (1a). This paper deals with the acetylation of the desmethyl derivative (1b). When a suspension of 1b in acetic anhydride was heated under reflux for 2 hr, the bis [1,
HIROSHI HIRANO +3 more
openaire +2 more sources
Utilizacão de pesticidas na agropecuária dos municípios da Bacia do Alto Taquari de 1988 a 1996 e risco de contaminação do Pantanal, MS, Brasil. [PDF]
, 2011 A partir da década de 1970, a remoção da vegetação nativa, principalmente dos cerrados, da Bacia do Alto Taquari (BAT), localizada em Mato Grosso do Sul e parte de Mato Grosso, se intensificou, para a implantação da agropecuária.
GALDINO, S. +2 more
core +1 more source