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Synthesis and Pharmacological Evaluation of Novel 1,5-Disubstituted-3-amino-1,2,4-triazoles Designed as Multitarget Directed Ligands for Alzheimer's Disease Targets. [PDF]

open access: yesACS Omega
Franco DP   +10 more
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Palladium-Catalyzed Benzylation of Heterocyclic Aromatic Compounds

Organic Letters, 2009
Broadly applicable palladium-catalyzed heteroarene benzylation reactions are described with a focus on the most challenging heterocyclic classes under traditional benzylation techniques such as sulfur-containing heterocycles and those bearing functional groups that would be incompatible with reactions requiring Lewis acids and/or strong bases.
David, Lapointe, Keith, Fagnou
openaire   +2 more sources

Replacing benzyl chloride with benzyl alcohol in heterogeneous catalytic benzylation of aromatic compounds

Pure and Applied Chemistry, 2012
Comparative catalytic liquid-phase benzylation of aromatic compouds (e.g., benzene and ethylbenzene) to diphenylmethane (DPM) derivatives with benzyl alcohol (BnOH) was investigated over various catalysts like zeolite (HSZ 600 mordenite, CBV 20A mordenite, H-beta zeolites with Si/Al ratios of 10.8 and 35.8, respectively) and nano-structured inorganic ...
Natalia Candu   +4 more
openaire   +1 more source

N-Benzyl and O-Benzyl Compounds: A New Group of Synthetic Auxin Biomimetics

Doklady Biological Sciences, 2003
The structural and topochemical similarity between natural (Scheme 1, compounds A – E ) and synthetic (Scheme 1, compounds F and G ) auxins is that their molecules include a system of aromatic rings, which binds to a polar group (carboxyl, amide group, nitrile, or hydroxyl) through a methylene, dimethylene, trimethylene, or oxalkylene bridge [1–4]. The
R G, Gafurov, A A, Makhmutova
openaire   +2 more sources

Benzylation of 1,3‐Dicarbonyl Compounds with Benzyl Alcohols Promoted by Perfluorosulfonic Acid Resin

ChemistrySelect, 2023
Abstract The catalytic performance of Perfluorosulfonic acid resin (PFSA), a solid superacid, was studied in the catalytic benzylation of 1,3‐dicarbonyl compounds with benzylic alcohols. The PFSA‐catalyzed reactions could proceed smoothly to provide the products under solvent‐free conditions or in toluene and dichloromethane, which ...
Yingge Zhang   +12 more
openaire   +1 more source

Gold-catalyzed benzylic oxidation to carbonyl compounds

Tetrahedron, 2009
The gold-catalyzed, mild and general benzylic oxidation toward carbonyl compounds with TBHP as oxidant is described. Corresponding products are obtained in moderate to excellent yields.
Huanrong Li, Zhiping Li, Zhangjie Shi
openaire   +1 more source

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