Results 171 to 180 of about 153,292 (304)

A targeted antiferromagnetic nanoprobe for ultra‐sensitive magnetic resonance imaging detection of sub‐millimeter esophageal tumors

open access: yesBMEMat, EarlyView.
We developed a cyclo‐RGD peptide‐conjugated antiferromagnetic nanoparticle (RANP) as a targeted T1 contrast agent. Under 9 T MRI conditions, RANP exhibited an r1 value of 1.88 mM−1 s−1 and a low r2/r1 ratio of 1.84, enabling the detection of esophageal tumors as small as 0.8 mm in vivo. Abstract Early, non‐invasive detection of esophageal cancer at sub‐
Wenkui Mo   +15 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

open access: yesBMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie   +12 more
wiley   +1 more source

Metal‐Free Covalent Organic Frameworks for Photocatalytic CO2 Reduction

open access: yesChemistryEurope, EarlyView.
This review presents an environmentally sustainable strategy to address the critical issue of escalating atmospheric CO2 levels. It explores the application of metal‐free covalent organic frameworks in a photocatalytic approach, offering a green and efficient strategy for carbon dioxide reduction and contributing to climate change mitigation.
Supriti Dutta   +3 more
wiley   +1 more source

Synthesis and Characterization of π‐Extended Azulenes via Nucleophilic Substitution and Intramolecular Cyclization of 5‐Alkynyl‐6‐Fluoroazulenes

open access: yesChemistryEurope, EarlyView.
A modular synthetic approach enables the preparation of azulene‐fused heterocycles via nucleophilic aromatic substitution followed by intramolecular cyclization of alkynyl fluoroazulenes. The method allows the incorporation of various heteroatoms (N, O, S, Se, and Te), leading to structurally diverse heteroannulated azulenes.
Martin C. Dietl   +8 more
wiley   +1 more source

Exploring Cadaba fruticosa bioactive compounds for oral cancer an in silico and in vitro approach. [PDF]

open access: yesSci Rep
Selvan ST   +5 more
europepmc   +1 more source

Advances in Parahydrogen‐Induced Polarization for Nuclear Magnetic Resonance of Peptides, Proteins, and Biopolymers

open access: yesChemistryEurope, EarlyView.
Hyperpolarization by parahydrogen‐induced polarization enhances the sensitivity of nuclear magnetic resonance spectroscopy of amino acids, peptides, mini‐proteins, and biopolymers using nonnatural amino acids with unsaturated side chains up to three orders of magnitude.
Gerd Buntkowsky
wiley   +1 more source

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