Results 181 to 190 of about 153,292 (304)

Rh(III)-Catalyzed Regioselective [4 + 2] Annulation of 2-Benzyl-2H-indazole-6-carboxylic Acids with Ynamides to Access Indazole-Fused Pyrans. [PDF]

J Org Chem
Hsieh HS, Liu KM, Chao CM, Barve IJ, Sun CM.   +4 more
europepmc   +1 more source

One‐Pot Ruthenium‐Catalyzed Synthesis of Benzyl/Allyl‐Halide Substituted (dihydro)naphthalenes via Radical Benzannulation

ChemistryEurope, EarlyView.
A one‐pot protocol to synthesize reactive benzyl‐ and allyl‐halide‐substituted (dihydro)naphthalenes from 2,3‐aryl‐1,3‐butadiene substrates and halogenated alkanes has been developed, using [Cp*RuCl(PPh3)2] as the catalyst. Mechanistic studies revealed an atom transfer radical addition and radical benzannulation sequence, followed by HCl elimination ...
Nicole S. van Leeuwen, David Vesseur, Thijmen Bonhoff, Jeffrey van Laar, Coert E. J. van Lare, Simon Mathew, Sonja Pullen, Joost N. H. Reek, Aalbert Zwijnenburg, Bas de Bruin   +9 more
wiley   +1 more source

Room temperature synthesis of α,β-unsaturated nitriles by manganese-catalysed base-free coupling of α-saturated nitriles with aldehydes. [PDF]

Chem Sci
Thiyagarajan S, Luo J, Liang Y, Efremenko I, Montag M, Milstein D.   +5 more
europepmc   +1 more source

Intramolecular N···F Pnictogen Bond Mitigates the Explosive Behavior of Azido‐L‐Phenylalanines

ChemistryEurope, EarlyView.
An intramolecular N···F pnictogen bond is the key for the chemical stabilization of the fluorinated azido‐L‐phenylalanines, mitigating the risk of explosion and thus facilitating the handling and storage of these materials. Organic azides are versatile intermediates but are plagued by intrinsic instability and potential explosiveness. Here, it is shown
Andrea Pizzi, Eleonora Veronese, Nicola Demitri, Marco Saccone, Pierangelo Metrangolo, Giancarlo Terraneo   +5 more
wiley   +1 more source

Optimization of 4-Amino-2-Pyridone Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9: Integrating Structure-Activity and Structure-Metabolism Relationships. [PDF]

ChemMedChem
Giannessi L, Lupo MG, Ugolotti M, Papotti B, Mattina B, Martina MG, Demurtas A, Padula C, Nicoli S, Crescenzio M, Ferri N, Zimetti F, Radi M.   +12 more
europepmc   +1 more source

The Challenging P‐Alkylation of Aromatic Phosphorus Heterocycles and Follow‐Up Reactions

ChemistryEurope, EarlyView.
P‐alkylation of λ3σ2‐phosphinines is hindered by weak nucleophilicity and scarce synthetic access, previously requiring multistep routes or extreme electrophiles. A direct ambient‐condition method is reported using 3,5‐bis(trimethylsilyl)‐phosphinine/B(C6F5)3 with esters or iso(thio)cyanates to generate stable 1‐R‐phosphininium salts.
Samantha Frank, Ádám Horváth, Duy Nguyen, Moritz J. Ernst, Simon Steinhauer, Zoltán Benkő, Christian Müller   +6 more
wiley   +1 more source

Low-valent cobalt catalyzed direct dehydroxylative cross-coupling of benzyl alcohols with aryl-chlorides. [PDF]

Chem Sci
Shinde PS, Shinde VS, Rueping M.
europepmc   +1 more source

Precision Catalysis in Dehydrogenation of Liquid Organic Hydrogen Carriers: Molecular Structure‐Geometry‐Electronic Interplay for Enhanced Hydrogen Evolution

Carbon Energy, EarlyView.
Atomic‐scale design principles for LOHC dehydrogenation: Tailoring geometric and electronic effects in metal catalysts to bridge the molecular structure of LOHC and dehydrogenation performance. ABSTRACT The advancement of hydrogen‐based energy systems necessitates innovative solutions for safe, efficient hydrogen storage and transportation.
Yongxiao Tuo, Jingying Qu, Huailu Sun, Hongwei Gai, Xiangyuan Qu, Junlun Zhu, Xiaohui Sun, De Chen, Xiang Feng   +8 more
wiley   +1 more source

Hydantion indolinones as AANAT inhibitors. [PDF]

Bioorg Med Chem Lett
Wandrey N, Boley J, Gómez-Galicia D, Hill M, Bach M, Gawrych S, Hagemeister M, Cole PA, Moxley MA, Thomas AA.   +9 more
europepmc   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source