Results 31 to 40 of about 3,315 (223)

Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1

Mediators of Inflammation, 2020
Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that functions as a copper-containing amine oxidase and is involved in leukocyte adhesion at sites of inflammation.
Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry   +6 more
doaj   +1 more source

Platelet monoamine oxidase activity in diabetics.

Acta Médica Portuguesa, 1980
Platelet monoamine oxidase (MAO) activity was determined, using benzylamine as substract. Results are expressed as nM benzaldehyde/mg protein hour, at 37”. A total of 79 diabetics (40 M and 39 F) ranging in age from 3 to 70 years was studied.
Maria Azevedo, Francisca Fernandes, Pedro Lisboa, Carlos Manso   +3 more
doaj   +1 more source

Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus [PDF]

, 2005
Aims/hypothesis: Plasma semicarbazide-sensitive amine oxidase (SSAO) is elevated in patients with type 1 and type 2 diabetes and has been implicated in the pathophysiology of diabetic late complications. The regulation of SSAO production remains unknown.
Agerholm-Larsen, B. (B.), Boomsma, F. (Frans), Dhamrait, S.S. (S.), Hut, H., Meiracker, A.H. (Anton) van den, Pedersen-Bjergaard, U. (Ullrik), Thorsteinsson, B. (Birger)   +6 more
core   +1 more source

Highly efficient oxidation of amines to aldehydes via flow-based biocatalysis [PDF]

, 2017
A new mild and efficient process for the preparation of aldehydes in water employed as flavour and fragrance components in food, beverage, cosmetics, as well as in pharmaceuticals was developed using a continuous-flow approach based on an immobilized ...
Akhtar, Allen, Andrade, Babich, Bajic, Bolivar, Bryan, Buckley, Calleri, Carvalho, Cerioli, Csajági, Dall′Oglio, Desjardins, Díaz-Rodríguez, Falus, Finnigan, Galletti, Hacisalihoglu, Hamamoto, Hu, Itabaiana, Junior, Kantlehner, Knowles, Kunjapur, Largeron, Largeron, Lawrence, Ley, Liu, Matsuo, Molinari, Noureldin, Orito, Planchestainer, Plouffe, Romano, Schümperli, Sharma, Sheldon, Smith, Solomon, Tamborini, Tamborini, Turner, Wang, Wiles, Yoshida, Zambelli, Zambelli, Zheng   +51 more
core   +2 more sources

Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue

Journal of Obesity, 2011
An enzyme hitherto named semicarbazide-sensitive amine oxidase (SSAO), involved in the oxidation of primary amines, is abundantly expressed in adipocytes.
Josep Mercader, Zsuzsa Iffiú-Soltész, Sandy Bour, Christian Carpéné   +3 more
doaj   +1 more source

A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase [PDF]

, 2015
A new colorimetric method has been developed to screen transaminases using an inexpensive amine donor. The assay is sensitive, has a low level of background coloration, and can be used to identify and profile transaminase activities against aldehyde and ...
Baud, D, Hailes, HC, Ladkau, N, Moody, TS, Ward, JM   +4 more
core   +1 more source

N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor [PDF]

, 2014
On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234) and QSAR predictions, in this work we have designed, synthesized, and evaluated a number of new indole derivatives from which ...
Agbaba, D., Alcaro, S., Bautista-Aguilera, O.M., Chioua, M., De Andrés, L., Filipic, S., Marco-Contelles, J., Nikolic, K., Ortuso, F., Ramsay, R.R., Rodríguez-Franco, M.I., Samadi, A., Soriano, E., Yañez, M.   +13 more
core   +3 more sources

Effects of semicarbazide-sensitive amine oxidase inhibitors on morphology of aorta and kidney in diabetic rats

BMC Endocrine Disorders, 2019
Background The present study aimed to investigate the inhibitory effects of aminoguanidine (AG) and 2-bromoethylamine (2-BEA) on the semicarbazide-sensitive amine oxidase (SSAO) activity both in vitro and in vivo, and the prevention role of AG and 2-BEA ...
Chaosheng Li, Zhenhua Wang, Xiaoli Li, Jun Chen   +3 more
doaj   +1 more source

Pesticide Exposure Alters Follicle-Stimulating Hormone Levels in Mexican Agricultural Workers [PDF]

, 2005
Organophosphorous pesticides (OPs) are suspected of altering reproductive function by reducing brain acetylcholinesterase activity and monoamine levels, thus impairing hypothalamic and/or pituitary endocrine functions and gonadal processes. Our objective
Baldi I, Butler AM, Guadalupe Ocampo-Gómez, Javier Morán-Martínez, Luisa Torres-Sánchez, Malaquías López-Cervantes, Mariano E. Cebrián, Marisela Uribe, Murray M, Nag M, Rogelio Recio, Spassova D, Victor Borja-Aburto   +12 more
core   +2 more sources

Engineered C–N Lyases for Stereoselective Synthesis of Tertiary Amines

Angewandte Chemie, Volume 137, Issue 34, August 18, 2025.
EDDS lyase was subjected to iterative cycles of site‐saturation mutagenesis and screened for increased activity for the addition of 2‐((methylamino)methyl)aniline to fumarate. The final mutant, EDDS lyase CEA, accepts various N‐methyl‐1‐phenylmethanamines derivatives, yielding N,N‐disubstituted L‐aspartic acids, as well as several ortho‐substituted ...
Laura Bothof, Xiaofang Gong, Marrit E. Onclin, Peter Fodran, Gerrit J. Poelarends   +4 more
wiley   +2 more sources