Results 11 to 20 of about 348 (143)

Computational study of some potential inhibitors of COVID‐19: A DFT analysis

Quantitative Biology, 2022
Background There is an urgent demand of drug or therapy to control the COVID‐19. Until July 22, 2021 the worldwide total number of cases reported is more than 192 million and the total number of deaths reported is more than 4.12 million.
Prabhat Ranjan, Kumar Gaurav, Tanmoy Chakraborty   +2 more
doaj   +2 more sources

Model of Chronic Itch in Aged Mice: Beneficial Effects of Drugs Affecting Descending Modulatory Systems [PDF]

Acta Dermato-Venereologica
Pruritus in the elderly, particularly those cases without skin dryness or other identifiable causes, makes treatment challenging due to the lack of evidence regarding the therapeutic effects of antipruritics. This study proposes an age-related alloknesis
Go Kojima, Eriko Komiya, Kotaro Honda, Takahide Kaneko, Yasushi Suga, Mitsutoshi Tominaga, Kenji Takamori   +6 more
doaj   +2 more sources

Treatment of allergic conjunctivitis with bepotastine besilate ophthalmic solution 1.5%

Clinical Ophthalmology, 2014
Mark T Bergmann,1 Jon I Williams,2 Paul J Gomes3On behalf of the Bepotastine Besilate Ophthalmic Solutions Clinical Study Group 1Eye Care Associates of Greater Cincinnati, Inc., Cincinnati, OH, USA; 2Bausch + Lomb, Irvine, CA, USA; 3Ora, Inc., Andover ...
Bergmann MT, Williams JI, Gomes PJ
doaj   +6 more sources

Critical appraisal of bepotastine in the treatment of ocular itching associated with allergic conjunctivitis

Clinical Ophthalmology, 2011
Jeremy B Wingard, Francis S MahUPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAAbstract: Bepotastine besilate 1.5% solution is an H1-antihistamine recently approved by the Food and Drug ...
Jeremy B Wingard, Francis S Mah
doaj   +5 more sources

The Efficacy of Bepotastine Besilate Compared With Hydroxyzine Pamoate for Preventing Infusion Reactions to the First Dose of Rituximab in Patients With Non-Hodgkin Lymphoma: Protocol for a Phase II, Double-Blind, Multicenter Randomized Trial [PDF]

JMIR Research Protocols
BackgroundRituximab, an anti-CD20 monoclonal antibody, can cause infusion reactions (IRs), especially during the initial rituximab infusion therapy.
Yumi Kitahiro, Kazuhiro Yamamoto, Kimikazu Yakushijin, Takeshi Ioroi, Masaaki Tanda, Kotaro Itohara, Tomohiro Omura, Hironobu Minami, Ikuko Yano   +8 more
doaj   +2 more sources

Antibody Production and Immunoassay Development for Authenticating Chlorpheniramine Maleate Adulteration in Herbal Tea [PDF]

Foods
Chlorphenamine maleate is a prohibited additive found in herbal teas and health foods. Excessive intake of this substance can result in adverse health effects.
Jianhao Lin, Zhiwei Liu, Tian Guan, Yi Lei, Liangwen Pan, Xiaoqin Yu, Shiwei Zhang, Xin-An Huang, Hongtao Lei, Jiahong Chen   +9 more
doaj   +2 more sources

A Novel Synthetic Method for Bepotastine, a Histamine H1 Receptor Antagonist

Bulletin of the Korean Chemical Society, 2013
An efficient and alternative synthesis of enantiomerically pure (+)-(S)-4-(4-((4-chlorophenyl)(pyrid-2-yl)methoxy]piperidin-1-yl)butanoic acid, bepotastine (1) is described. The key resolution of (R/S)-bepotastine l-menthyl ester (3) is achived via diastereomeric salt crystallization using N-benzyloxycarbonyl-L-aspartic acid (NCbzLAA) as the resolving ...
Tae Hee Ha, Kwee-Hyun Suh, Gwan Sun Lee
exaly   +3 more sources

Bepotastine besilate ophthalmic solution 1.5% for alleviating nasal symptoms in patients with allergic conjunctivitis

Journal of Asthma and Allergy, 2018
Megan E Cavet,1 Paul J Gomes,2 Warner W Carr,3 Jon I Williams4 1Bausch + Lomb, Rochester, NY, 2Ora, Andover, MA, 3Allergy and Asthma Associates of Southern California, Mission Viejo, CA, 4Bausch + Lomb, Irvine, CA, USA Background: Bepotastine besilate ...
Cavet ME, Gomes PJ, Carr WW, Williams JI
doaj   +5 more sources

Dermatopathological Findings of an Erythema Multiforme-Like Drug Eruption During Enfortumab Vedotin Plus Pembrolizumab Therapy for Metastatic Urothelial Carcinoma: A Case Report. [PDF]

Clin Case Rep
ABSTRACT The combination therapy of enfortumab vedotin and pembrolizumab (EV+Pem) is effective for metastatic urothelial carcinoma. However, the dermatopathological findings for treatment‐related adverse events, particularly skin disorders, often remain unclear.
Murofushi R, Kato Y, Seo T, Iwasaki K, Goto M, Monma N, Maekawa S, Obara W.   +7 more
europepmc   +2 more sources

Efficacy of Bepotastine versus Olopatadine Ophthalmic Solutions in Mild to Moderate Vernal Keratoconjunctivitis as a Sole Therapy [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Vernal Keratoconjunctivitis (VKC) is a chronic, seasonally exacerbated allergic ocular inflammation of the conjunctiva. It affects predominantly the school going male population and is not so common.
Rahul Dara, Vandana Mahaur, Jaya Devendra, Malhar Vyas, Manish Prajapat, Tejinder Singh Ahluwalia   +5 more
doaj   +1 more source