Comparative inhibitory effects of bepotastine and diphenhydramine on rituximab-induced infusion reactions [PDF]
International Journal of HematologyAbstract Purpose Infusion-related reaction (IRR) is a common adverse event induced by rituximab. Although first-generation histamine 1 receptor antagonists (H1RAs) are commonly used to prevent IRR, evidence on IRR suppression by the second-generation H1RA bepotastine is scarce.
Hideo Yagi +2 more
exaly +8 more sources
Critical appraisal of bepotastine in the treatment of ocular itching associated with allergic conjunctivitis [PDF]
Clinical Ophthalmology, 2011 Jeremy B Wingard, Francis S MahUPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAAbstract: Bepotastine besilate 1.5% solution is an H1-antihistamine recently approved by the Food and Drug ...
Jeremy B Wingard, Francis S Mah
doaj +6 more sources
Treatment of allergic conjunctivitis with bepotastine besilate ophthalmic solution 1.5%
Clinical Ophthalmology, 2014 Mark T Bergmann,1 Jon I Williams,2 Paul J Gomes3On behalf of the Bepotastine Besilate Ophthalmic Solutions Clinical Study Group 1Eye Care Associates of Greater Cincinnati, Inc., Cincinnati, OH, USA; 2Bausch + Lomb, Irvine, CA, USA; 3Ora, Inc., Andover ...
Bergmann MT, Williams JI, Gomes PJ
doaj +7 more sources
The Efficacy of Bepotastine Besilate Compared With Hydroxyzine Pamoate for Preventing Infusion Reactions to the First Dose of Rituximab in Patients With Non-Hodgkin Lymphoma: Protocol for a Phase II, Double-Blind, Multicenter Randomized Trial [PDF]
JMIR Research ProtocolsBackgroundRituximab, an anti-CD20 monoclonal antibody, can cause infusion reactions (IRs), especially during the initial rituximab infusion therapy.
Yumi Kitahiro +8 more
doaj +3 more sources
Bepotastine besilate ophthalmic solution 1.5% for alleviating nasal symptoms in patients with allergic conjunctivitis [PDF]
Journal of Asthma and Allergy, 2018 Megan E Cavet,1 Paul J Gomes,2 Warner W Carr,3 Jon I Williams4 1Bausch + Lomb, Rochester, NY, 2Ora, Andover, MA, 3Allergy and Asthma Associates of Southern California, Mission Viejo, CA, 4Bausch + Lomb, Irvine, CA, USA Background: Bepotastine besilate ...
Cavet ME, Gomes PJ, Carr WW, Williams JI
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Antibody Production and Immunoassay Development for Authenticating Chlorpheniramine Maleate Adulteration in Herbal Tea [PDF]
FoodsChlorphenamine maleate is a prohibited additive found in herbal teas and health foods. Excessive intake of this substance can result in adverse health effects.
Jianhao Lin +9 more
doaj +3 more sources
Development and Characterization of In Situ Ophthalmic Gel of Bepotastine Besilate [PDF]
Journal of Drug Delivery and Therapeutics, 2019 The aim of the present work was development and characterization of in-situ Ophthalmic Gel of Bepotastine Besilate to overcome the drawbacks obtained by conventional eye drop. There are two independent variables were used i.e. Carbopol 934 and HPMC K100. Carbopol 934 were used as gelling agent and HPMC K100 were used as bioadhesive polymer.
Ravindranath B Saudagar, Lajri Garge
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Indian Journal of Drugs in Dermatology, 2017 Oral bepotastine is a nonsedative second-generation antihistamine with an action on other inflammatory mediators. It also acts as a mast cell stabilizer and leukotrienes inhibitor. Its distribution in the brain is very limited.
Kiran Godse, Neeti Kumari
openaire +2 more sources
Drugs, 2010 Oral bepotastine is a second-generation histamine H(1) receptor antagonist that also suppresses some allergic inflammatory processes. Numerous short- and long-term clinical trials and surveillance studies have shown that twice-daily bepotastine is an effective and generally well tolerated antihistamine in the treatment of patients with allergic ...
Katherine A. Lyseng-Williamson
openaire +3 more sources
Computational study of some potential inhibitors of COVID‐19: A DFT analysis
Quantitative Biology, 2022 Background There is an urgent demand of drug or therapy to control the COVID‐19. Until July 22, 2021 the worldwide total number of cases reported is more than 192 million and the total number of deaths reported is more than 4.12 million.
Prabhat Ranjan +2 more
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