Results 21 to 30 of about 448 (162)

A comparative study of efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye drops in allergic conjunctivitis in a tertiary care hospital of the southern part of India [PDF]

Asian Journal of Medical Sciences
Background: Allergic conjunctivitis is increasing with the rise in the levels of allergens. Drug therapy is usually needed in addition to avoidance of general allergens to treat this condition.
Sudipto Chatterjee , Vijendra R , Soumyadeep Mahapatra , Kiran Kumar L   +3 more
doaj   +2 more sources

Double‐Blind Placebo‐Controlled Trial of Bepotastine Salicylate in Patients With Allergic Rhinitis

The Laryngoscope, 2020
Objectives/HypothesisTo evaluate the efficacy and safety of a slow‐release form of bepotastine salicylate (HL151, Belion CR) in patients with perennial allergic rhinitis (PAR).Study DesignDouble‐blind, placebo‐controlled multicenter comparative study.MethodsTwo hundred seventy‐two PAR patients (aged 19–65 years) were studied to determine the efficacy ...
Ji‐Hun Mo, Jin Hyeok Jeong, Tae Hoon Kim, Seon‐Tae Kim, Soo Whan Kim, Kun Hee Lee, Seung‐No Hong, Hyo Yeol Kim, Dae Woo Kim, Dong‐Young Kim, Chang‐Hoon Kim, Seok Hyun Cho, Chae‐Seo Rhee   +12 more
core   +5 more sources

A comparative study to assess the efficacy and safety of bepotastine and cetirizine in allergic rhinitis [PDF]

International Journal of Basic & Clinical Pharmacology, 2019
Background: Pharmacotherapy is the mainstay of allergic rhinitis and many caregivers use over-the-counter antihistamines. Bepotastine is a novel oral second generation non-sedative antihistamine and an effective treatment option for allergic rhinitis.
A. T. Priyanka, K. R. Mamatha, G. M. Puttamadaiah   +2 more
openaire   +3 more sources

Bepotastine Besilate

Indian Journal of Drugs in Dermatology, 2017
Oral bepotastine is a nonsedative second-generation antihistamine with an action on other inflammatory mediators. It also acts as a mast cell stabilizer and leukotrienes inhibitor. Its distribution in the brain is very limited.
Kiran Godse, Neeti Kumari
openaire   +2 more sources

Oral Bepotastine

Drugs, 2010
Oral bepotastine is a second-generation histamine H(1) receptor antagonist that also suppresses some allergic inflammatory processes. Numerous short- and long-term clinical trials and surveillance studies have shown that twice-daily bepotastine is an effective and generally well tolerated antihistamine in the treatment of patients with allergic ...
Katherine A. Lyseng-Williamson
openaire   +3 more sources

UPLC-MS/MS Method for Determination of Bepotastine in Human Plasma [PDF]

Journal of Chromatographic Science, 2013
A sensitive and rapid method for quantitation of bepotastine in human plasma has been established using ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS). Valsartan was used as an internal standard. Bepotastine and internal standard in plasma sample were extracted using ethylacetate (liquid-liquid
Yun Kyoung, Choi, Yoon Hee, Chung, Yun Sung, Nam, Da Young, Kang, Hohyun, Kim, Seo Eun, Lee, Hak Rim, Kim, Yong Seong, Lee, Ji Hoon, Jeong   +8 more
openaire   +4 more sources

A Comparative Study of Olopatadine Hydrochloride and Bepotastine Besilate in the Treatment of Allergic Conjunctivitis

International Journal of Research and Review, 2022
Background -Ocular allergy is a commonly encountered pathology in clinical practice, which often is under diagnosed and consequently undertreated. These are rarely vision-threatening but can significantly decrease the quality of life for patients. Olopatadine and Bepotastine eyedrop have both antihistaminic and mast cell stabilization action. Their use
Archana V. Manekar, Sharayu Ashok Bhore
openaire   +2 more sources

Intact Cell Binding for In Vitro Prediction of Sedative and Non-sedative Histamine H1–Receptor Antagonists Based on Receptor Internalization

Journal of Pharmacological Sciences, 2008
We evaluated changes in the binding properties of sedative and non-sedative histamine H1–receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma, Yuko Sato, Yusuke Kobayashi, Hiroshi Komazaki, Masaki Saito   +4 more
doaj   +2 more sources

New drugs: Asenapine, iloperidone, and bepotastine besilate

Journal of the American Pharmacists Association, 2010
Antipsychotic agents Asenapine (Saphris—Schering) and iloperidone (Fanapt—Vanda) are new atypical antipsychotic agents that join an already large class of these drugs that includes aripiprazole (Abilify), clozapine (e.g., Clozaril), olanzapine (Zyprexa), quetiapine (Seroquel), ziprasidone (Geodon), and risperidone (e.g., Risperdal) and its active ...
Daniel A, Hussar, Cheryl A, Abbas
openaire   +3 more sources

Evaluation of Efficacy and Sedative Profiles of H1 Antihistamines by Large-Scale Surveillance Using the Visual Analogue Scale (VAS)

Allergology International, 2008
Background: H1 antihistamines are widely used as therapeutics for allergic diseases. Sedation is a well-known side effect of H1 antihistamines and sometimes it is life-threatening for patients.
Norimasa Izumi, Hiroyuki Mizuguchi, Hayato Umehara, Satoshi Ogino, Hiroyuki Fukui   +4 more
doaj   +2 more sources