Results 21 to 30 of about 348 (143)

Comparative analysis of safety and efficacy of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2% and Bepotastine besilate 1.5% in allergic conjunctivitis

Indian Journal of Ophthalmology, 2021
Purpose: To compare the efficacy and safety of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2%, and Bepotastine besilate 1.5% ophthalmic solutions in the treatment of allergic conjunctivitis. Methods: This is a prospective, observer-masked, comparative
Shruti Ayyappanavar, Sriya Sridhar, Kiran Kumar, C R Jayanthi, Suresh Babu Gangasagara, B L Sujatha Rathod, B Preethi, Preeti Mittal   +7 more
doaj   +1 more source

Perforating collagenosis. [PDF]

Skin Health Dis
We show a case of a 69‐year‐old man with perforating collagenosis, which is a rare dermatosis commonly associated with diabetes mellitus. Papules and plaques with keratotic plugs are distinctive clinical characteristic of perforating collagenosis. Representative clinical images in our article can enhance the understanding of key concepts of perforating
Oya K, Saito A.
europepmc   +2 more sources

A prospective, randomized, open-label, active-controlled study to compare the efficacy and safety of levocetirizine and bepotastine in chronic spontaneous urticaria

Clinical Dermatology Review, 2023
Background: Management of chronic spontaneous urticaria (CSU) is challenging because of its unpredictable course and negative influence on the quality of life. Second-generation antihistaminics are the first-line treatment. Levocetirizine, a time-tested
Gaurav Menghani, Navneet Kaur, Kapil Vyas, Kalpana Gupta, Kriti Maheshwari, Raju Singh   +5 more
doaj   +1 more source

A double-arm, randomized, and controlled trial to compare the efficacy and safety of bepotastine with levocetirizine in patients of chronic spontaneous urticaria

National Journal of Physiology, Pharmacy and Pharmacology, 2022
Background: Second generation antihistamines are first line therapy for chronic spontaneous urticaria (CSU). Sedation has been always a concern as a side effect of antihistamine for both patients and treating dermatologist.
Ashish Kumar Rai, Shital Poojary, Lily Dubey, Pawan Gupta   +3 more
doaj   +1 more source

A case of chronic spontaneous urticaria with wheals lasting for more than a week. [PDF]

J Dermatol
Abstract Urticaria is characterized by the development of wheals which usually disappear within a day, and are not present beyond a few days. A 58‐year‐old man began to develop edematous, partially ring‐shaped erythematous lesions accompanied by severe body itching without any particular cause, approximately 2 months before his first visit to our ...
Morioke S, Moriwaki M, Tanaka A, Hide M.
europepmc   +2 more sources

Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38

British Journal of Pharmacology, Volume 180, Issue 15, Page 1899-1929, August 2023., 2023
Antimalarial drug discovery has until recently been driven by high‐throughput phenotypic cellular screening, allowing millions of compounds to be assayed and delivering clinical drug candidates. In this review, we will focus on target‐based approaches, describing recent advances in our understanding of druggable targets in the malaria parasite ...
Jane F. Armstrong, Brice Campo, Stephen P. H. Alexander, Lauren B. Arendse, Xiu Cheng, Anthony P. Davenport, Elena Faccenda, David A. Fidock, Karla P. Godinez‐Macias, Simon D. Harding, Nobutaka Kato, Marcus C. S. Lee, Madeline R. Luth, Ralph Mazitschek, Nimisha Mittal, Jacquin C. Niles, John Okombo, Sabine Ottilie, Charisse Flerida A. Pasaje, Alexandra S. Probst, Mukul Rawat, Frances Rocamora, Tomoyo Sakata‐Kato, Christopher Southan, Michael Spedding, Mark A. Tye, Tuo Yang, Na Zhao, Jamie A. Davies   +28 more
wiley   +1 more source

Assessment of flare frequency and severity of generalized pustular psoriasis in Japanese patients: A retrospective chart review study

JEADV Clinical Practice, Volume 2, Issue 2, Page 261-272, June 2023., 2023
Abstract Background Generalized pustular psoriasis (GPP) is a rare and often refractory disease, and GPP flares can be life threatening. The rarity of GPP prevents the development and evaluation of effective GPP‐specific treatments and obstructs disease understanding.
Akimichi Morita, Yukari Okubo, Shinichi Imafuku, Yayoi Tada, Keiichi Yamanaka, Kazumitsu Sugiura, Yukie Yamaguchi, Masahito Yasuda, Hitoshi Tsuchihashi, Morihisa Saitoh, Wataru Sakamoto, Ryuhei Okuyama, the study investigators   +12 more
wiley   +1 more source

Comparative observational analysis of clinical outcomes in patients of vernal keratoconjunctivitis treated with eye drops olopatadine or bepotastine besilate

Journal of Medical Evidence, 2022
Objective: Observation and comparison of resolution of signs and relief of symptoms in patients of Vernal Keratoconjunctivitis (VKC) treated with 0.1% olopatadine eye drops or 1.5% bepotastine besilate eye drops.
Preeti Yadav, Ajai Agrawal, Puneet Dhamija, Anupam Singh, Sanjeev Kumar Mittal, Ramanuj Samanta   +5 more
doaj   +1 more source

Identification of SARS‐CoV‐2 Papain‐like Protease (PLpro) Inhibitors Using Combined Computational Approach**

ChemistryOpen, Volume 11, Issue 2, February 2022., 2022
Combined in silico machinery, consisting of long‐ and short‐range molecular interaction methods is capable of filtering large compound databases, yielding a good candidate for a receptor. The advantage of this approach is a fast assessment of a candidate, starting from basic information on both protein and small organic molecule – FASTA sequence and ...
Milan Sencanski, Vladimir Perovic, Jelena Milicevic, Tamara Todorovic, Radivoje Prodanovic, Veljko Veljkovic, Slobodan Paessler, Sanja Glisic   +7 more
wiley   +1 more source

Bepotastine-induced urticaria, cross-reactive with other antihistamines [PDF]

Asia Pacific Allergy, 2016
Second-generation antihistamines are widely prescribed for the control of symptoms of allergic inflammation such as itchy hives, coryza, and itchy eyes. In rare circumstances, these drugs might provoke allergic inflammation. Hypersensitivity to bepotastine besilate, a second-generation antihistamine has never been reported.
Kang, Ju Wan, Lee, Jaechun
openaire   +2 more sources