Results 21 to 30 of about 428 (162)

A comparative study of efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye drops in allergic conjunctivitis in a tertiary care hospital of the southern part of India [PDF]

Asian Journal of Medical Sciences
Background: Allergic conjunctivitis is increasing with the rise in the levels of allergens. Drug therapy is usually needed in addition to avoidance of general allergens to treat this condition.
Sudipto Chatterjee , Vijendra R , Soumyadeep Mahapatra , Kiran Kumar L   +3 more
doaj   +2 more sources

Double‐Blind Placebo‐Controlled Trial of Bepotastine Salicylate in Patients With Allergic Rhinitis

The Laryngoscope, 2020
Objectives/HypothesisTo evaluate the efficacy and safety of a slow‐release form of bepotastine salicylate (HL151, Belion CR) in patients with perennial allergic rhinitis (PAR).Study DesignDouble‐blind, placebo‐controlled multicenter comparative study.MethodsTwo hundred seventy‐two PAR patients (aged 19–65 years) were studied to determine the efficacy ...
Ji‐Hun Mo, Jin Hyeok Jeong, Tae Hoon Kim, Seon‐Tae Kim, Soo Whan Kim, Kun Hee Lee, Seung‐No Hong, Hyo Yeol Kim, Dae Woo Kim, Dong‐Young Kim, Chang‐Hoon Kim, Seok Hyun Cho, Chae‐Seo Rhee   +12 more
core   +5 more sources

UPLC-MS/MS Method for Determination of Bepotastine in Human Plasma [PDF]

Journal of Chromatographic Science, 2013
A sensitive and rapid method for quantitation of bepotastine in human plasma has been established using ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS). Valsartan was used as an internal standard. Bepotastine and internal standard in plasma sample were extracted using ethylacetate (liquid-liquid
Yun Kyoung, Choi, Yoon Hee, Chung, Yun Sung, Nam, Da Young, Kang, Hohyun, Kim, Seo Eun, Lee, Hak Rim, Kim, Yong Seong, Lee, Ji Hoon, Jeong   +8 more
openaire   +4 more sources

Development of Analytical Method to Monitor Dissolution of Bepotastine Besilate Tablet

Journal of Drug Delivery and Therapeutics, 2019
Bepotastine Besilate is an anti-histaminic drug and it is marketed as tablet of strength 10mg. In this study an attempt is made to monitor the dissolution of Bepotastine Besilate tablet. Dissolution study was done for marketed sample using phosphate buffer 6.8, phosphate buffer 4.5 and 0.1 N HCl as dissolution media.
K.K. Pardeshi, M. C. Damle
openaire   +2 more sources

A comparative study to assess the efficacy and safety of bepotastine and cetirizine in allergic rhinitis [PDF]

International Journal of Basic & Clinical Pharmacology, 2019
Background: Pharmacotherapy is the mainstay of allergic rhinitis and many caregivers use over-the-counter antihistamines. Bepotastine is a novel oral second generation non-sedative antihistamine and an effective treatment option for allergic rhinitis.
A. T. Priyanka, K. R. Mamatha, G. M. Puttamadaiah   +2 more
openaire   +3 more sources

The Effect of Prophylactic Treatment with Bepotastine in Patients with Japanese Cedar Pollinosis.

Practica Oto-Rhino-Laryngologica, 2002
The clinical effect of Bepotastine in patients with Japanese cedar allergy was investigated before and after the start of the pollen season. Symptom score, medication score and symptom-medication score were significantly lower in patients treated before the pollen season than in those treated after it started.These results indicate that Bepotastine is ...
OHTA, Nobuo, INAMURA, Kazutoshi, NODA, Daisuke, GON, Seigi, ISHIDA, Akihiro, AKATSUKA, Naoko, Saito, Fumiaki, AOYAGI, Masaru   +7 more
openaire   +3 more sources

Intact Cell Binding for In Vitro Prediction of Sedative and Non-sedative Histamine H1–Receptor Antagonists Based on Receptor Internalization

Journal of Pharmacological Sciences, 2008
We evaluated changes in the binding properties of sedative and non-sedative histamine H1–receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma, Yuko Sato, Yusuke Kobayashi, Hiroshi Komazaki, Masaki Saito   +4 more
doaj   +2 more sources

Dermatopathological Findings of an Erythema Multiforme-Like Drug Eruption During Enfortumab Vedotin Plus Pembrolizumab Therapy for Metastatic Urothelial Carcinoma: A Case Report. [PDF]

Clin Case Rep
ABSTRACT The combination therapy of enfortumab vedotin and pembrolizumab (EV+Pem) is effective for metastatic urothelial carcinoma. However, the dermatopathological findings for treatment‐related adverse events, particularly skin disorders, often remain unclear.
Murofushi R, Kato Y, Seo T, Iwasaki K, Goto M, Monma N, Maekawa S, Obara W.   +7 more
europepmc   +2 more sources

Efficacy of Bepotastine versus Olopatadine Ophthalmic Solutions in Mild to Moderate Vernal Keratoconjunctivitis as a Sole Therapy [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Vernal Keratoconjunctivitis (VKC) is a chronic, seasonally exacerbated allergic ocular inflammation of the conjunctiva. It affects predominantly the school going male population and is not so common.
Rahul Dara, Vandana Mahaur, Jaya Devendra, Malhar Vyas, Manish Prajapat, Tejinder Singh Ahluwalia   +5 more
doaj   +1 more source

Comparative analysis of safety and efficacy of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2% and Bepotastine besilate 1.5% in allergic conjunctivitis

Indian Journal of Ophthalmology, 2021
Purpose: To compare the efficacy and safety of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2%, and Bepotastine besilate 1.5% ophthalmic solutions in the treatment of allergic conjunctivitis. Methods: This is a prospective, observer-masked, comparative
Shruti Ayyappanavar, Sriya Sridhar, Kiran Kumar, C R Jayanthi, Suresh Babu Gangasagara, B L Sujatha Rathod, B Preethi, Preeti Mittal   +7 more
doaj   +1 more source