Results 31 to 40 of about 348 (143)

Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non‐Japanese

Clinical and Translational Science, Volume 15, Issue 2, Page 490-500, February 2022., 2022
Abstract Cenobamate (XCOPRI and ONTOZRY) is a novel antiseizure medication for the treatment of focal‐onset seizures. Nonetheless, there is limited information on the pharmacokinetics (PKs), safety, and efficacy of cenobamate in Asian people, including Japanese people.
Eunsol Yang, Jung Sunwoo, Ki Young Huh, Yu Kyong Kim, SeungHwan Lee, In‐Jin Jang, Kyung‐Sang Yu   +6 more
wiley   +1 more source

Bepotastine Besilate

Indian Journal of Drugs in Dermatology, 2017
Oral bepotastine is a nonsedative second-generation antihistamine with an action on other inflammatory mediators. It also acts as a mast cell stabilizer and leukotrienes inhibitor. Its distribution in the brain is very limited.
Kiran Godse, Neeti Kumari
openaire   +1 more source

UPLC-MS/MS Method for Determination of Bepotastine in Human Plasma [PDF]

Journal of Chromatographic Science, 2013
A sensitive and rapid method for quantitation of bepotastine in human plasma has been established using ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS). Valsartan was used as an internal standard. Bepotastine and internal standard in plasma sample were extracted using ethylacetate (liquid-liquid
Yun Kyoung, Choi, Yoon Hee, Chung, Yun Sung, Nam, Da Young, Kang, Hohyun, Kim, Seo Eun, Lee, Hak Rim, Kim, Yong Seong, Lee, Ji Hoon, Jeong   +8 more
openaire   +2 more sources

Hydroxyzine‐induced fixed drug eruption and cross‐reaction with oxatomide

, 2023
Journal of Cutaneous Immunology and Allergy, Volume 6, Issue 2, Page 59-60, April 2023.
Mizuki Terada, Shujiro Hayashi, Maki Okamoto, Ken Igawa   +3 more
wiley   +1 more source

Coronavirus in Continuous Flux: From SARS‐CoV to SARS‐CoV‐2

Advanced Science, Volume 7, Issue 20, October 21, 2020., 2020
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has posed a serious threat to public health. Since the outbreak, numerous attempts have been taken to gain insights of the viral structure, the clinical manifestations, and the immune responses caused by SARS‐CoV‐2.
Yetian Dong, Tong Dai, Jun Liu, Long Zhang, Fangfang Zhou   +4 more
wiley   +1 more source

International Coherence of Pediatric Drug Labeling for Drug Safety: Comparison of Approved Labels in Korea and the United States

Clinical Pharmacology &Therapeutics, Volume 107, Issue 3, Page 530-540, March 2020., 2020
The objective of this study was to analyze information on pediatric use in Korean drug product labels and compare it with that in US Food and Drug Administration (FDA) labeling information. Prescription information on pediatric use contained in the commonly used drugs’ product labels approved by Korean government was compared with that approved by the ...
Yun‐Kyoung Song, Nayoung Han, Gilbert J. Burckart, Jung Mi Oh   +3 more
wiley   +1 more source

Observer-masked trial comparing efficacy of topical olopatadine (0.1%), bepotastine (1.5%), and alcaftadine (0.25%) in mild to moderate allergic conjunctivitis

Indian Journal of Ophthalmology, 2019
Purpose: With increasing environmental pollution, the incidence of allergic conjunctivitis is increasing. Newer anti-allergic medications with combined anti-histaminic and mast cell stabilization action can help reducing the use of topical steroids for ...
Lakshey Dudeja, Anuja Janakiraman, Ishani Dudeja, Kaustubh Sane, Manohar Babu   +4 more
doaj   +1 more source

A comparative study of efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye drops in allergic conjunctivitis in a tertiary care hospital of the southern part of India

Asian Journal of Medical Sciences
Background: Allergic conjunctivitis is increasing with the rise in the levels of allergens. Drug therapy is usually needed in addition to avoidance of general allergens to treat this condition.
Sudipto Chatterjee , Vijendra R , Soumyadeep Mahapatra , Kiran Kumar L   +3 more
doaj   +1 more source

High-flow continuous hemodiafiltration successfully decreased blood pregabalin levels in a patient with severe pregabalin intoxication: a case report

Renal Replacement Therapy, 2022
Background Severe pregabalin intoxication may cause serious symptoms, such as coma. Since pregabalin is a small molecule with no protein binding sites and has low volume of distribution, hemodialysis can be effective in eliminating pregabalin from the ...
Takashi Shimazui, Nobuya Kitamura, Kuniyuki Kako, Shinya Iwase, Toshinao Suzuki, Shota Hoshino, Hiromi Futagami, Kazuhiko Kibayashi, Ken-ichiro Nakao   +8 more
doaj   +1 more source

A pharmacoeconomic study of olopatadine hydrochloride 0.1% eye drops and bepotastine besilate 1.5% eye drops in the management of allergic conjunctivitis: A cost-effectiveness analysis

Asian Journal of Medical Sciences
Background: Allergic conjunctivitis (AC) affects 10–20% of the Indian population, necessitating cost-effective treatment strategies. Aims and Objectives: We aimed to evaluate the comparison between the pharmacoeconomic profiles of olopatadine ...
Sudipto Chatterjee , Pritama Paul , Abhishek Bhattacharjee , Soumyadeep Mahapatra   +3 more
doaj   +1 more source