Results 21 to 30 of about 28,920 (238)

Genetic evidence for inhibition of bacterial division protein FtsZ by berberine. [PDF]

PLoS ONE, 2010
BACKGROUND: Berberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting an antibacterial mechanism that involves inhibition of cell division.
Jaroslaw M Boberek, Jem Stach, Liam Good
doaj   +1 more source

Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. [PDF]

PLoS ONE, 2011
Berberine, a botanical alkaloid purified from Coptidis rhizoma, is reported to activate the AMP-activated protein kinase (AMPK). Whether AMPK is required for the protective effects of berberine in cardiovascular diseases remains unknown.
Qilong Wang, Miao Zhang, Bin Liang, Najeeb Shirwany, Yi Zhu, Ming-Hui Zou   +5 more
doaj   +1 more source

RETRACTED: Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m6A Methylation

Frontiers in Oncology, 2021
BackgroundCancer stem cells (CSCs) are able to survive after cancer therapies, resulting in tumor progression and recurrence, as is seen in colorectal cancer.
Ziyi Zhao, Ziyi Zhao, Jinhao Zeng, Jinhao Zeng, Qiang Guo, Kunming Pu, Yi Yang, Nianzhi Chen, Gang Zhang, Maoyuan Zhao, Qiao Zheng, Jianyuan Tang, Jianyuan Tang, Qiongying Hu   +13 more
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In Vivo and in Vitro Study on Drug-Drug Interaction of Lovastatin and Berberine from Pharmacokinetic and HepG2 Cell Metabolism Studies

Molecules, 2016
Background: We assumed that the pharmacokinetics of lovastatin could be changed by the induction effect of berberine. Methods: An UPLC-MS/MS method was developed and validated for the pharmacokinetics tudy of lovastatin to investigate the in vivo drug ...
Hanming Cui, Jialong Wang, Qiuyan Zhang, Mengmeng Dang, Hui Liu, Yu Dong, Lu Zhang, Fang Yang, Jianhua Wu, Xiaolin Tong   +9 more
doaj   +1 more source

Antiviral activity of berberine [PDF]

Archives of Virology, 2020
AbstractPlants are a rich source of new antiviral, pharmacologically active agents. The naturally occurring plant alkaloid berberine (BBR) is one of the phytochemicals with a broad range of biological activity, including anticancer, anti-inflammatory and antiviral activity.
Alicja Warowicka, Robert Nawrot, Anna Goździcka-Józefiak   +2 more
openaire   +2 more sources

Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability

Molecules, 2018
Berberine has many pharmacological effects, such as antidiabetic, antimicrobial, anti-inflammatory, and antioxidant, but the question remains on how its low oral bioavailability has greatly limited its clinical application. As a safer hypoglycemic agent,
Hong-Xin Cui, Ya-Nan Hu, Jing-Wan Li, Ke Yuan, Ying Guo   +4 more
doaj   +1 more source

Protective effects of berberine on intestinal ischemia and reperfusion injury in rats [PDF]

Archives of Biological Sciences, 2017
This study aims to investigate the potential protective effects of berberine on ischemia and reperfusion (IR) injury in rats. Thirty male rats were randomly divided into three experimental groups as follows: the sham group, the IR group and the ...
Chen Tanzhou, Lv Bin
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Berberine Inhibits the Release of Glutamate in Nerve Terminals from Rat Cerebral Cortex. [PDF]

PLoS ONE, 2013
Berberine, an isoquinoline plant alkaloid, protects neurons against neurotoxicity. An excessive release of glutamate is considered to be one of the molecular mechanisms of neuronal damage in several neurological diseases.
Tzu-Yu Lin, Yu-Wan Lin, Cheng-Wei Lu, Shu-Kuei Huang, Su-Jane Wang   +4 more
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Berberine: A Promising Treatment for Neurodegenerative Diseases

Frontiers in Pharmacology, 2022
Berberine, as a natural alkaloid compound, is characterized by a diversity of pharmacological effects. In recent years, many researches focused on the role of berberine in central nervous system diseases.
Ziqian Cheng, Chenglan Kang, Songtian Che, Jingyun Su, Qihan Sun, Tongtong Ge, Yi Guo, Jiayin Lv, Zhihui Sun, Wei Yang, Bingjin Li, Xin Li, Ranji Cui   +12 more
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Molecular and Crystal Structures of Three Berberine Derivatives

Molecules, 2001
Berberine azide, berberine thiocyanate, and 8-cyano-8H-berberine were prepared from berberine chloride, a quaternary protoberberine alkaloid. The molecular and crystal structures of all compounds are reported and discussed.
Jiří Dostál, Zdirad Žák, Marek Nečas, Milan Potáček, Stanislav Man   +4 more
doaj   +1 more source