Results 81 to 90 of about 28,920 (238)

Nano-Encapsulated Berberine Is a Potential Therapeutic Agent for Adipose Tissue Browning in C57BL/6J Mice

Medicina
Background and Objectives: Berberine is a promising phytochemical for obesity prevention due to its effects on adipogenesis and adipose tissue browning.
Aslıhan Alpaslan, Kübra Uçar Baş, Elif Didem Örs Demet, Dilem Tuğal Aslan, Tuba Reçber, Süleyman Can Öztürk, Tugba Gulsun, Mustafa Çelebier, Zeynep Göktaş   +8 more
doaj   +1 more source

Berberine produces antidepressant-like effects in ovariectomized mice

Scientific Reports, 2017
Berberine has been reports to have antidepressant-like effects. However, it is seldom known whether berberine produces antidepressant-like effects in ovariectomized mice, which exhibit depressive-like responses. To examine the antidepressant-like effects
Jie Fan, Bingjin Li, Tongtong Ge, Zhuo Zhang, Jiayin Lv, Jing Zhao, Pu Wang, Wei Liu, Xuefeng Wang, Katarzyna Mlyniec, Ranji Cui   +10 more
doaj   +1 more source

Optimization of ex vivo permeability characteristics of berberine in presence of quercetin using 32 full factorial design [PDF]

, 2019
Sarika Narade, Yogesh Pore
openalex   +1 more source

Auxin‐Induced Nicotine Inhibition Is Mediated by NaARF5 Through the Suppression of NaERF1‐Like Expression and Interaction With NaERF1‐Like in Nicotiana attenuata

Plant Biotechnology Journal, EarlyView.
ABSTRACT Nicotine is the most abundant alkaloid produced by Nicotiana species against insect herbivores. Although it has been known for decades that auxin can strongly inhibit nicotine biosynthesis, the underlying mechanisms have remained unclear.
Miyun Yang, Ahui Tong, Lei Wang, Jinsong Wu   +3 more
wiley   +1 more source

Efficacy and safety of berberine for dyslipidemia: study protocol for a randomized double-blind placebo-controlled trial [PDF]

, 2021
Ying Zhao, Yuanyuan Yang, Baolin Yang, Yawei Du, Da-Wei Ren, Hongmei Zhou, Jing Wang, Huimin Yang, Yaoxian Wang, Yingying Zhang, Shengxian Wu   +10 more
openalex   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Effects of type 2 diabetes mellitus on the pharmacokinetics of berberine in rats

Pharmaceutical Biology, 2017
Context: Berberine is an active alkaloid isolated from Rhizoma coptidis [Coptis chinensis Franch. (Ranunculaceae)] that is widely used for the treatment of diabetes, hyperlipidemia and hypertension.
Yuzhen Jia, Binger Xu, Jisen Xu
doaj   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, Volume 16, Issue 1, Page 145-160, January 2026.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source