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Dual action of herbal compounds in <i>Klebsiella pneumoniae</i> infection and associated inflammatory diseases. [PDF]

Front Immunol
Saqib U, Ratlamwala S, Kibe N, Baig MS, Hajela K, Sharma S.   +5 more
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A review on analytical methods for natural berberine alkaloids

Journal of Separation Science, 2019
AbstractBerberine alkaloids, a group of protoberberine alkaloids under the classification of isoquinoline alkaloids, include berberine, coptisine, palmatine, columbamine, dehydrocorydaline, jatrorrhizine, and epiberberine from natural sources. Studies have shown that berberine alkaloids have various pharmacological functions, such as antibacterial ...
Bing Wang
exaly   +3 more sources

Inhibitory Effects of Berberine-Type Alkaloids on Elastase

Planta Medica, 1993
Berberine-type alkaloids and some structurally related alkaloids were tested for inhibitory activity on porcine pancreatic elastase (PPE) and human sputum elastase (HSE). The chlorides of berberine, coptisine, and sanguinarine significantly inhibited the elastolytic activity of both the enzymes, but tetrahydroberberine had no effect on the activity. It
T, Tanaka, K, Metori, S, Mineo, M, Hirotani, T, Furuya, S, Kobayashi   +5 more
exaly   +3 more sources

Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

European Journal of Medicinal Chemistry, 2021
Alkaloids are one of the most important classes of plant bioactives. Among these isoquinoline alkaloids possess varied structures and exhibit numerous biological activities. Basically these are biosynthetically produced via phenylpropanoid pathway. However, occasionally some mixed pathways may also occur to provide structural divergence.
Arvind S Negi
exaly   +3 more sources

Berberine Alkaloids via 6,7-Dimethoxyisoquinoline-l-aldoxime

Nature, 1959
FOR the past two years1, it has been clear that the development of a new and convenient method for the synthesis of the berberine alkaloids hinged on the preparation of 6,7-methylenedioxy (I)- and 6,7-dimethoxyisoquinoline aldehydes (II). The use of the first of these in the synthesis of tetrahydroberberine and related alkaloids has been reported2. The
C. K. BRADSHER, N. L. DUTTA
exaly   +2 more sources

Toxicological Effects of Berberine and Sanguinarine

Frontiers in Molecular Biosciences, 2018
Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced by
Nitika Singh
exaly   +3 more sources

Berberine: An Antihypoglycemic Alkaloid

Journal of Functional And Environmental Botany, 2013
The term diabetes mellitus describes a metabolic disorder of multiple aetiology characterised by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. The effects of diabetes mellitus include long-term damage, dysfunction and failure of various organs ...
Abhimanyu Sharma, Amla Batra
openaire   +1 more source

Berberine: A naturally occurring phototoxic alkaloid

Journal of Chemical Ecology, 1984
The isoquinoline alkaloid berberine, present in nine different plant families was found to be phototoxic to mosquito larvae. In the presence of near UV the LC50 for acute 24-hr toxicity was 8.8 ppm compared to 250 ppm for dark controls. Mosquito larvae that were treated with 10 ppm berberine plus near UV for 24 hr and then transferred to berberine-free
B J, Philogène, J T, Arnason, G H, Towers, Z, Abramowski, F, Campos, D, Champagne, D, McLachlan   +6 more
openaire   +2 more sources